CotAD_22160, CotAD_22160_BGI-AD1_v1.0 (mRNA) Gossypium hirsutum

Query:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE 693
            MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE
Sbjct:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE 693          

Query:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE 693
            MQKTSKRSHSNSFSIAKELIFFWVFLVFSSG VFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLK+SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLV LLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE
Sbjct:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGQVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKESDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVPLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE 693          

Query:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQP 690
            MQKTSKRSHSNSFSIAKELIFFWVFLVFSSG VFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQY+GLLNASENGNSANHIFAVEFDTVKDLE GDINDNHVGVNVNSMKSIASTPAAYFLEN TKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLK+SDIIEA ELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQ TNTQVAVKRISHESKQGLREF+SEIASIGRLRHRNLV LLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGG NTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQP
Sbjct:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGQVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYMGLLNASENGNSANHIFAVEFDTVKDLEFGDINDNHVGVNVNSMKSIASTPAAYFLENGTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKESDIIEAFELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQSTNTQVAVKRISHESKQGLREFVSEIASIGRLRHRNLVPLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGTNTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQP 690          

Query:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQP 690
            MQKTSKRSHSNSFSIAKELIFFWVFLVFSSG VFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQY+GLLNASENGNS NHIFAVEFDTVKDLE GDINDNHVGVNVNSMKSIASTPAAYFLEN TKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLK+SDIIEA ELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQ TNTQVAVKRISHESKQGLREF+SEIASIGRLRHRNLV LLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGG NTIRFEDFVHSYPNSPYLDVEDRDVDIEA STKHLDQP
Sbjct:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGQVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYMGLLNASENGNSTNHIFAVEFDTVKDLEFGDINDNHVGVNVNSMKSIASTPAAYFLENGTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKESDIIEAFELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQSTNTQVAVKRISHESKQGLREFVSEIASIGRLRHRNLVPLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGTNTIRFEDFVHSYPNSPYLDVEDRDVDIEADSTKHLDQP 690          

Query:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE 693
            MQKTSKRSHSNSFSIAKELIFFWVFLVFSSG VFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLE                               TKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLK+SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLV LLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE
Sbjct:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGQVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLE-------------------------------TKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKESDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVPLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE 662          

Query:   49 GNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE 693
            GNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQY+GLLNASENGNS NHIFAVEFDTVKDLE GDINDNHVGVNVNSMKSIASTPAAYFLEN TKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLK+SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPE+VPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE
Sbjct:  342 GNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYMGLLNASENGNSTNHIFAVEFDTVKDLEFGDINDNHVGVNVNSMKSIASTPAAYFLENGTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKESDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPELVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE 986          

Query:   52 MSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIG 405
            MSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLK+SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQG +  ++ +A I 
Sbjct:    1 MSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKESDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGNKMSLTGVADIA 354          

Query:   52 MSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQP 690
            MSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQY+GLLNASENGNSANHIFAVEFDTVKDLE GDINDNHVGVNVNSMKSIASTPAAYFLEN TKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLK+SDIIEA ELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQ TNTQVAVKRISHESKQGLREF+SEIASIGRLRHRNLV LLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGG NTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQP
Sbjct:    1 MSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYMGLLNASENGNSANHIFAVEFDTVKDLEFGDINDNHVGVNVNSMKSIASTPAAYFLENGTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKESDIIEAFELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQSTNTQVAVKRISHESKQGLREFVSEIASIGRLRHRNLVPLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGTNTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQP 639          

Query:  128 LSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQP 690
             S SPSQY+GLLNASENGNSANHIFAVEFDTVKDLE GDINDNHVGVNVNSMKSIASTPAAYFLEN TKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLK+SDIIEA ELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQ TNTQVAVKRISHESKQGLREF+SEIASIGRLRHRNLV LLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGG NTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQP
Sbjct:   53 FSRSPSQYMGLLNASENGNSANHIFAVEFDTVKDLEFGDINDNHVGVNVNSMKSIASTPAAYFLENGTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKESDIIEAFELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQSTNTQVAVKRISHESKQGLREFVSEIASIGRLRHRNLVPLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGTNTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQP 615          

Query:    6 KRSHSNSFSIAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLD--------VEDRDVDIEA 681
            K  + + F +AK+L+FFWVFLV  S  VFSQLDQFIFNGFH +GN MSLTGVADI   GL+CLTNT+SRVSGHAFYSSP++FKNS +SKV SFS+AF  A VPEYPKLGGHGLAF LSPSK+LSG PSQYLGLLNA++NGNS NHIFAVEFDTVKDLE GDI+DNHVG+N+NSM S AS  AAYFLEN TK+EL +KSG  IQAWIDYDSA+NRL+VKLS  SEKPRSSILS DV+LS ILQD MFVGFSASTGLLASSHYVLGWSFNMSGEA+SLSL SLPSLPRPK+NHTVLILCVTF+ V+++M I+FISFYLVRKLK +DIIEA EL+IGPHRFSY+ELKKAT GFRDKELLGFGGFGRVYKGTL  TNTQVAVKRISHESKQGLREF+SEIASIGRLRHRNLV+LLGWCRCRGDLL+VYD+MPNGSLDKYLFDEPKRVL W+ERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRL DFGLAKLYEHG NP+TTRVVGTLGYLAPELT+TGKPT ++DVFAFGA LLEV CGR+PIEPKALPEELILVDWVWERWQSGA LEVVDPKLNG+FDELEAIVVIKLGLMCSNDA +ARPT+RQVVRYL GEVALPEVVPSPGG DS+KG+G  G     FED+VHSYP+S Y D         EDRDVDIEA
Sbjct:   64 KNLNPHPFFMAKKLVFFWVFLV-CSDQVFSQLDQFIFNGFHEAGNNMSLTGVADIGSKGLICLTNTSSRVSGHAFYSSPVRFKNSSSSKVFSFSTAFAFAMVPEYPKLGGHGLAFTLSPSKELSGFPSQYLGLLNATDNGNSTNHIFAVEFDTVKDLEFGDIDDNHVGINLNSMVSNASASAAYFLENSTKQELSLKSGRMIQAWIDYDSARNRLEVKLSPFSEKPRSSILSFDVDLSPILQDPMFVGFSASTGLLASSHYVLGWSFNMSGEAESLSLLSLPSLPRPKENHTVLILCVTFSAVLIMMSIIFISFYLVRKLKNADIIEAWELDIGPHRFSYRELKKATRGFRDKELLGFGGFGRVYKGTLPSTNTQVAVKRISHESKQGLREFVSEIASIGRLRHRNLVQLLGWCRCRGDLLLVYDFMPNGSLDKYLFDEPKRVLSWEERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLGDFGLAKLYEHGQNPSTTRVVGTLGYLAPELTRTGKPTTSSDVFAFGAFLLEVVCGRKPIEPKALPEELILVDWVWERWQSGAVLEVVDPKLNGEFDELEAIVVIKLGLMCSNDALEARPTIRQVVRYLAGEVALPEVVPSPGGSDSRKGNGRRGAG---FEDYVHSYPDSSYFDKGSACSSAFEDRDVDIEA 743          

Query:   15 IAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLD--------VEDRDVDIEA 681
            +AK+L+FFWVFLV  S  VFSQLDQFIFNGFH +GN MSLTGVADI   GL+CLTNT+SRVSGHAFYSSP++FKNS +SKV SFS+AF  A VPEYPKLGGHGLAF LSPSK+LSG PSQYLGLLNA++NGNS NHIFAVEFDTVKDLE GDI+DNHVG+N+NSM S AS  AAYFLEN TK+EL +KSG  IQAWIDYDSA+NRL+VKLS  SEKPRSSILS DV+LS ILQD MFVGFSASTGLLASSHYVLGWSFNMSGEA+SLSL SLPSLPRPK+NHTVLILCVTF+ V+++M I+FISFYLVRKLK +DIIEA EL+IGPHRFSY+ELKKAT GFRDKELLGFGGFGRVYKGTL  TNTQVAVKRISHESKQGLREF+SEIASIGRLRHRNLV+LLGWCRCRGDLL+VYD+MPNGSLDKYLFDEPKRVL W+ERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRL DFGLAKLYEHG NP+TTRVVGTLGYLAPELT+TGKPT ++DVFAFGA LLEV CGR+PIEPKALPEELILVDWVWERWQSGA LEVVDPKLNG+FDELEAIVVIKLGLMCSNDA +ARPT+RQVVRYL GEVALPEVVPSPGG DS+KG+G  G     FED+VHSYP+S Y D         EDRDVDIEA
Sbjct:    1 MAKKLVFFWVFLV-CSDQVFSQLDQFIFNGFHEAGNNMSLTGVADIGSKGLICLTNTSSRVSGHAFYSSPVRFKNSSSSKVFSFSTAFAFAMVPEYPKLGGHGLAFTLSPSKELSGFPSQYLGLLNATDNGNSTNHIFAVEFDTVKDLEFGDIDDNHVGINLNSMVSNASASAAYFLENSTKQELSLKSGRMIQAWIDYDSARNRLEVKLSPFSEKPRSSILSFDVDLSPILQDSMFVGFSASTGLLASSHYVLGWSFNMSGEAESLSLLSLPSLPRPKENHTVLILCVTFSAVLIMMSIIFISFYLVRKLKNADIIEAWELDIGPHRFSYRELKKATRGFRDKELLGFGGFGRVYKGTLPSTNTQVAVKRISHESKQGLREFVSEIASIGRLRHRNLVQLLGWCRCRGDLLLVYDFMPNGSLDKYLFDEPKRVLSWEERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLGDFGLAKLYEHGQNPSTTRVVGTLGYLAPELTRTGKPTTSSDVFAFGAFLLEVVCGRKPIEPKALPEELILVDWVWERWQSGAVLEVVDPKLNGEFDELEAIVVIKLGLMCSNDALEARPTIRQVVRYLAGEVALPEVVPSPGGSDSRKGNGRRGAG---FEDYVHSYPDSSYFDKGSACSSAFEDRDVDIEA 671          

Query:   33 VFSQLDQFIFNGFHGSG-NKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPY 669
            V  Q+DQ ++ GF   G + +++ GVA I  +G+L LTN +SR+ GHAFY SP                   +A VPEYPKLGGHGLAF ++ SK L   PSQYLGLLN+S+NGN +NHIFAVEFDTV+D E GDINDNHVG+++NSM+S AS        N +   L +KSG  I AW+DYDS  N + V LS  S KP++ +L+ +V+LS +  D M+VGFSASTGLLASSHY+LGWSF ++G A            +PK+  T LI+ V+ +V V+++L + I  Y  RK+K +D+IEA ELEIGPHR+SYQELKKAT GF+DKELLG GGFGRVYKGTL  +  QVAVKR+SHESKQGLREF+SEIASIGRLRHRNLV+LLGWCR RGDLL+VYD+M NGSLDKYLFDEPK +L W+ RFKIIKGVAS LLYLHE +EQ VIHRD+KA NVLLD ELNGRL DFGLA+LYEHG NP+TTRVVGTLGYLAPEL +TGK T ++DVFAFGA+LLEVACGRRPIEPKALPEEL+LVDWVWE+++ G  L++VDPKLN  FDE E IVV+KLGLMCSND P  RP+MRQVVRYL+GEV +PE +  PG     +G          F++F+HS  +S +
Sbjct:   18 VSCQVDQLLYAGFKDVGASNLTMNGVAKIEHNGILKLTNDSSRLMGHAFYPSPFQLKNSTSGKVLSFSSSFALAIVPEYPKLGGHGLAFTIATSKDLKALPSQYLGLLNSSDNGNISNHIFAVEFDTVQDFEFGDINDNHVGIDINSMQSNASA-------NVSLVGLTLKSGKPILAWVDYDSQLNLISVALSPNSSKPKTPLLTFNVDLSPVFHDIMYVGFSASTGLLASSHYILGWSFKINGPAPPLDLSSLPQLPQPKKKQTSLIIGVSVSVFVIVLLAISIGIYFYRKIKNADVIEAWELEIGPHRYSYQELKKATRGFKDKELLGQGGFGRVYKGTLPNSKIQVAVKRVSHESKQGLREFVSEIASIGRLRHRNLVQLLGWCRRRGDLLLVYDFMANGSLDKYLFDEPKIILNWEHRFKIIKGVASALLYLHEGYEQVVIHRDVKASNVLLDFELNGRLGDFGLARLYEHGANPSTTRVVGTLGYLAPELPRTGKATTSSDVFAFGALLLEVACGRRPIEPKALPEELVLVDWVWEKYKQGRILDLVDPKLNVYFDEKEVIVVLKLGLMCSNDVPVTRPSMRQVVRYLDGEVEVPEDLKKPGDISHHEG----------FDEFLHSLASSSF 638          

Query:   33 VFSQLDQFIFNGFHGSG-NKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPY 669
            V  Q+DQ +++GF   G + +++ GV  I  +G+L LTN +SR  GHAFY SP                    A VPEYPKLGGHGLAF ++ SK L   P+QYLGLLN+S+NGN +NHIFAVEFDTV+D E GDINDNHVG+++NSM+S  S        N +   L +KSG  I AW+DYDS  N + V LS  S KP++ +L+ +V+LS +  D M+VGFSASTGLLASSHY+LGWSF ++G A            +PK+  T LI+ V+ +VVV+++L + I  Y  RK+K +D+IEA ELEIGPHR+SYQELKKAT GF+DKELLG GGFGRVYKGTL  +  QVAVKR+SHESKQGLREF+SEIASIGRLRHRNLV+LLGWCR +GDLL+VYD+M NGSLDKYLFDEPK +L W+ RFKIIKGVAS L+YLHE +EQ VIHRD+KA NVLLD ELNGRL DFGLA+LYEHG NP+TTRVVGTLGYLAPEL +TGK T ++DVFAFGA+LLEV CGRRPIEPKALPEE++LVDWVWE+++ G  L+VVDPKLNG FDE E +VV+KLGLMCSND P ARP+MRQVVRYL+GEV +PE +  PG     +G          FE+F+HS  +S +
Sbjct:   18 VSCQVDQVLYSGFKDVGASNLTMNGVTTIERNGILKLTNESSRSIGHAFYPSPFQLKNSTSGKALSFSSSFAFAIVPEYPKLGGHGLAFTIATSKDLKALPNQYLGLLNSSDNGNFSNHIFAVEFDTVQDFEFGDINDNHVGIDINSMQSNTSA-------NVSLVGLTLKSGKPILAWVDYDSRLNLISVALSPNSSKPKTPLLTFNVDLSPVFHDTMYVGFSASTGLLASSHYILGWSFKINGPAPPLDLSSLPQLPKPKKKQTSLIIGVSVSVVVIVLLAISIGIYFYRKIKNADVIEAWELEIGPHRYSYQELKKATRGFKDKELLGQGGFGRVYKGTLPNSKIQVAVKRVSHESKQGLREFVSEIASIGRLRHRNLVQLLGWCRRQGDLLLVYDFMANGSLDKYLFDEPKIILNWEHRFKIIKGVASALMYLHEGYEQVVIHRDVKASNVLLDFELNGRLGDFGLARLYEHGANPSTTRVVGTLGYLAPELPRTGKATTSSDVFAFGALLLEVVCGRRPIEPKALPEEMVLVDWVWEKYKQGRILDVVDPKLNGHFDEKEVMVVLKLGLMCSNDVPAARPSMRQVVRYLDGEVEVPEDLKKPGAVSHHEG----------FEEFLHSLASSSF 638          

Query:   19 LIFFWVFLVFSSGHVFSQLDQFIFNGFHG-SGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXX--XXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFL--ENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPY 669
            L+ F   LVF    V SQ +Q  + GF G   N M+L GVA+I  +G+L LTN +S+V GHAFY +P                     +A VPE+PKLGGHGLAF ++P+K+L   PSQYLGLL+++  GN +NH+FAVEFDT KD E GDI+DNHVG+++NS+ SIAS  A Y+   E+ TK+ + ++SG  I AW+DYD+A++ + V +S  S KP+  +LS  V+LS I +D M+VGFSASTG+LASSHY+LGWSF ++G A             PK+ HT LI+ V+ +VV +++  V +  Y+ R+ K +D+IEA ELEIGPHR+SYQELKKAT GF+DK LLG GGFG VYKGTL  +NTQVAVKRISH+S QGLREF+SEIASIGRLRHRNLV+LLGWCR RGDLL+VYD+M NGSLDKYLFDEP+ VL W++RFK+IK VAS LLYLHE +EQ VIHRD+KA NVLLD ELNGRL DFGLA+LYEHGTNP+TTRVVGTLGYLAPE+ +TGK T ++DVFAFGA+LLEVACG RP+EPKA+PE+++LVD VW +++ G+ L++VDPKLNG F+E E ++V+KLGL+CSN +P ARP+MRQVVR+LEGEV +P+ +  PG    + G+  G      F++F+HS  +S +
Sbjct:   38 LLKFLSLLVFLLIPVSSQQNQLFYAGFKGLKSNNMTLDGVAEIEPNGVLKLTNDSSKVMGHAFYPTPFRFKNSSGGGNKAFSFSSSFALAIVPEFPKLGGHGLAFAIAPTKELKAHPSQYLGLLDSTGIGNFSNHLFAVEFDTAKDFEFGDIDDNHVGIDINSLSSIASASAGYYSGDEDSTKQNVTLQSGVPILAWVDYDAAQSVVHVTISASSTKPKRPLLSYHVDLSPIFEDLMYVGFSASTGMLASSHYILGWSFKINGPALPLDLSSLPQLPGPKKKHTSLIIGVSASVVFLVLCAVLLGIYMYRRYKNADVIEAWELEIGPHRYSYQELKKATKGFKDKGLLGQGGFGSVYKGTLPNSNTQVAVKRISHDSNQGLREFVSEIASIGRLRHRNLVQLLGWCRRRGDLLLVYDFMENGSLDKYLFDEPEIVLSWEQRFKVIKDVASALLYLHEGYEQVVIHRDVKASNVLLDGELNGRLGDFGLARLYEHGTNPSTTRVVGTLGYLAPEVPRTGKATPSSDVFAFGALLLEVACGLRPLEPKAMPEDMVLVDCVWNKFKQGSILDLVDPKLNGVFNEREMLMVLKLGLLCSNSSPTARPSMRQVVRFLEGEVGVPDELKKPG----EGGYQEG------FDEFLHSLESSSF 683          

Query:   33 VFSQLDQFIFNGFHGSG-NKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFL--ENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDV------EDRDVD 678
            V SQ +Q  + GF G G N M+L GVA+I  +G+L LTN +S+V GHAFY +P                   +A VPE+PKLGGHGLAF ++PSK L   PSQYLG+L++S  GN +NH+FAVEFDT KD E GDI+DNHVG+++NS+ S AS  A Y+   ++ +K+ L ++S   I AW+DYD+AK+ + V +S  S KP+  +LS  V+LS IL++ M+VGFSASTGLLASSHY+LGWSF ++G A             PK+ HT LI+ V+ +VVV+ +  V    Y+ R+ K +D+IEA ELEIGPHR+SYQELKKAT GF+DKELLG GGFG VYKGTL  +NTQVAVKRISH+S QGLREF+SEIASIGRLRHRNLV+LLGWCR  GDLL+VYD+M NGSLDKYLF+EP+ +L W++RFK+IK VAS LLYLHE +EQ VIHRD+KA NVLLD ELNGRL DFGLA+LYEHGTNP+TTRVVGTLGYLAPE+ +TGK T ++DVFAFGA+LLEVACG RP+EPKA+PE+++LVD VW +++ G  L +VDPKLNG F+E E ++V+KLGL+CSN +P ARP+MRQVVR+LEGEV +P+ +  PG    ++G          F++F+HS  +S +  +       +RD+D
Sbjct:   22 VSSQPNQLFYAGFKGLGSNNMTLDGVAEIEPNGVLKLTNDSSKVMGHAFYPTPFRFKNSSGGKAFSFSSSFALAIVPEFPKLGGHGLAFTIAPSKDLKAHPSQYLGILDSSNIGNFSNHLFAVEFDTAKDFEFGDIDDNHVGIDINSLASNASASAGYYTGDDDSSKQNLTLQSRVPILAWVDYDAAKSVVHVTISASSTKPKRPLLSYHVDLSPILKESMYVGFSASTGLLASSHYILGWSFKINGPAPPLDLSSLPQLPGPKKKHTSLIIGVSVSVVVLALCAVLFGIYMYRRYKNADVIEAWELEIGPHRYSYQELKKATKGFKDKELLGQGGFGSVYKGTLPNSNTQVAVKRISHDSNQGLREFVSEIASIGRLRHRNLVQLLGWCRRLGDLLLVYDFMENGSLDKYLFNEPETILSWEQRFKVIKDVASALLYLHEGYEQVVIHRDVKASNVLLDGELNGRLGDFGLARLYEHGTNPSTTRVVGTLGYLAPEVPRTGKATPSSDVFAFGALLLEVACGLRPLEPKAMPEDMVLVDCVWNKFKQGRILNMVDPKLNGVFNEREMLMVLKLGLLCSNGSPTARPSMRQVVRFLEGEVGVPDELRKPGEGGYQEG----------FDEFLHSLESSSFDQMNTGSYGRNRDMD 666          

Query:   35 SQLDQFIFNGFHGSGN-KMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXX--XXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLI---VFISFYLVRKLKKSDIIEASELEI-GPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDV 672
            SQ ++F FNGF G+ +  ++L G A I   G+L LTN T RV GHAFY +P+                     A +P++PKLGGHG AF +S S+ L  + PSQYLGLLN ++ GN +NH+FAVEFDTV+D E GDIN NHVG+N+N++ S  S  AA+F     K++L +KSG   QAW+DYDS KN L+V+LS  S KP S ILS  V+LS I+QD M+VGFS+STGLL+SSHY+LGWSF ++G+A+              +    LI  ++ ++++  +L    +   ++L+RK++ S++IEA E+E+ GPHRF Y+EL KAT GF+DK L+GFGGFGRVYKG L  +N +VAVKR+S+ESKQG++EF+SEI++IGRLRHRNLV+LLGWCR + DLL+VYD+M NGSLDKYLF++PKR+L W++RFKIIKGVASGL+YLHEEWEQTVIHRD+KAGNVLLD+++NGRL DFGLAKLYEHG+NP+TTRVVGTLGYLAPELT+TGKPT ++DV+AFGA++LEV CGRRPIE KALPEEL+LV+WVWERW+ G  L VVDP+L G FDE EA++V+K+GL CS +AP+ RP+MRQVVRYLE EVA PEV+                     F+ + HSY  + + DV
Sbjct:   27 SQQEEFFFNGFGGAASSNITLNGGAVIEHRGILRLTNDTQRVIGHAFYPTPIQFKHRNKNATKVFSFSTAFAFAIIPQHPKLGGHGFAFTISRSRSLEDAYPSQYLGLLNPNDVGNFSNHLFAVEFDTVQDFEFGDINGNHVGINLNNLASNKSVEAAFFTSTNNKQKLNLKSGEVTQAWVDYDSLKNNLEVRLSTTSSKPTSPILSYKVDLSQIIQDSMYVGFSSSTGLLSSSHYILGWSFKINGDAKTLSLKNLPSLSASSKPQKRLIFALSLSLIIPTVLAATALACYYFLLRKMRNSEVIEAWEMEVVGPHRFPYKELHKATKGFKDKNLIGFGGFGRVYKGVLPKSNIEVAVKRVSNESKQGMQEFVSEISTIGRLRHRNLVQLLGWCRKQNDLLLVYDFMRNGSLDKYLFEQPKRILSWEQRFKIIKGVASGLVYLHEEWEQTVIHRDVKAGNVLLDNQMNGRLGDFGLAKLYEHGSNPSTTRVVGTLGYLAPELTRTGKPTTSSDVYAFGALVLEVLCGRRPIEVKALPEELVLVEWVWERWRVGNVLAVVDPRLGGVFDEEEALLVVKVGLSCSAEAPEERPSMRQVVRYLEREVAPPEVLVEGKKEGGG---------DGEFKGYAHSYSTASFFDV 663          

Query:   33 VFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXR--PKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEV 634
            V S    F +NGF  S   + L G A+   +G++ LTN T +  GHAF+ SP+                   A   E+P L GHG+AFV+SP+K++  S PSQYLGL + + NGN++NH+F VE DT+ + E GDINDNHVG++VN +KS+ S  A Y+ +   K  L + SG  +Q W++YD  K ++DV L+ ++  KP   +LS++ +LS IL   M+VGF++STG + SSHYVLGWSF ++G+AQ           R   KQ   VLI+ +   ++++I+++     + +++ K  +++E  E + GPHRF Y++L  AT GFR+KELLG GGFGRVYKG +  +  +VAVK++SHES+QG+REF++EIASIGRLRHRNLV LLG+CR +G+LL+VYDYMPNGSLDKYL+++P+  L W +RF+I KGVASGL YLHEEWEQ V+HRDIKA NVLLD+ELNGRL DFGL++LYEHGT+P TT VVGTLGYLAPE T+TGK T ++DVFAFGA +LEV CGRRPIE        ILVDWV+  W+ G  LE  DP L  ++   E  +V+KL L+CS+  P ARP+MRQVV+YLE +V LP++
Sbjct:   17 VASDYTSFTYNGFQSS--HLYLDGSAEFTTNGMVKLTNHTKQQKGHAFFPSPIVFKNTTNGSVFSFSTTFVFAIRSEFPNLSGHGIAFVVSPTKEVPHSLPSQYLGLFDDTNNGNNSNHVFGVELDTILNTEFGDINDNHVGIDVNELKSVKSASAGYYSDGGFKN-LSLISGYPMQVWVEYDGLKKQIDVTLAPINVGKPERPLLSLNKDLSRILNSSMYVGFTSSTGSILSSHYVLGWSFKVNGKAQQLAISELPMLPRLVGKQESKVLIVGLPLILLILILMVALAVVHAIKRKKFVELLEDWEQDYGPHRFKYKDLSLATKGFREKELLGSGGFGRVYKGVMPISKIEVAVKKVSHESRQGMREFVAEIASIGRLRHRNLVPLLGYCRRKGELLLVYDYMPNGSLDKYLYNKPRVTLNWSQRFRITKGVASGLFYLHEEWEQVVLHRDIKASNVLLDAELNGRLGDFGLSRLYEHGTDPHTTHVVGTLGYLAPEHTRTGKATTSSDVFAFGAFMLEVVCGRRPIEQGRESGSEILVDWVYNCWKKGEILEARDPNLGANYRPDEVELVLKLALLCSHSEPLARPSMRQVVQYLEKDVPLPDL 619          

Query:   33 VFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXR--PKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVV 635
            V S    F +NGF  S   + L G A+   +G+L LTN T +  GHAF+ SP+                   A   E+P L GHG+ FV+SP+K +  S PSQYLGL + + NGN++NHIF VE DT+ + E GDINDNHVGV+VN +KS+ S  A Y+ +   K  L + SG  +Q W++YD  K ++DV L+ ++  KP   +LS+  +LS IL   M+VGFS+STG + SSHYVLGWSF ++G+AQ           R   K+   VLI+ +   ++ +I+++     +++++ K ++++E  E + GPHRF Y++L  AT GFR+KELLG GGFGRVYKG +  +  +VAVK++S ES+QG+REF++EI SIG LRHRNLV LLG+CR +G+LL+VYDYMPNGSLDKYL+++P+  L W +RFKI KGVASGL YLHEEWEQ V+HRDIKA NVLLD+ELNGRL DFGL++LYEHGT+P TT VVGTLGYLAPE T+TGK T ++DVFAFGA +LEV CGRRPIE        ILVDWV+  W+ G  LE +DP L  ++   E  +V+KL L+CS+  P ARP+MRQVV+YLE +V LP++ 
Sbjct:   17 VASDDTSFTYNGFQSS--YLYLDGSAEFTTNGMLKLTNHTKQQKGHAFFPSPIVFKNTTSGSVFSFSTTFVFAIRSEFPNLSGHGIVFVVSPTKGVPHSLPSQYLGLFDDTNNGNNSNHIFGVELDTILNTEFGDINDNHVGVDVNELKSVKSAAAGYYSDEGFKN-LSLISGYPMQVWVEYDGLKKQIDVTLAPINVGKPEGPLLSLSKDLSPILNSSMYVGFSSSTGSILSSHYVLGWSFKVNGKAQQLAISELPMLPRLGGKEESKVLIVGLPLILLSLILMVALAVVHVIKRKKFTELLEDWEQDYGPHRFKYKDLSLATKGFREKELLGSGGFGRVYKGVMPISKIEVAVKKVSRESRQGMREFVAEIVSIGCLRHRNLVPLLGYCRRKGELLLVYDYMPNGSLDKYLYNKPRVTLNWSQRFKITKGVASGLFYLHEEWEQVVVHRDIKASNVLLDAELNGRLGDFGLSRLYEHGTDPHTTHVVGTLGYLAPEHTRTGKATTSSDVFAFGAFMLEVVCGRRPIEKGGESGSEILVDWVYNCWKKGEILESMDPNLGANYRPDEVELVLKLALLCSHSEPLARPSMRQVVQYLEKDVPLPDLC 620          

Query:  192 ENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSY-PNSPY 669
            +N TK+ L + SG  I AW+DYD++++ ++V +S  S KP+  +LS  V+LS I +D MFVGFSASTGLLASSHY+LGWSF ++G A             PK+ HT LI  V+ +  + +   +F   Y+ R+ K +D+IEA ELEIGPHR+SYQELKKAT GF+DKELLG GGFG VYKGTL  +NTQVAVKRISH+SKQGLREF+SEIASIGRLRHRNLV LLGWCR RGDLL+VYD+M NGSLDKYLFD PK +L W++RFK+IK VAS LLYLHE +EQ VIHRD+KA NVLLD  LNGRL DFGLA+LYEHG NP+TTRVVGT GY+APE+ +TGK T  +DVFAFGA+LLEVACG RP+EPKALPE+++LVD VW +++ G  L++VDPKLNG F+E E ++V+KLG++CSN AP ARP+MRQVVR+L+GEV LP+ +  P     ++G          F++F++S  P+S Y
Sbjct:   88 DNSTKQNLTLTSGEPIIAWVDYDASQSVVNVTISESSTKPKRPLLSHHVDLSPIFEDLMFVGFSASTGLLASSHYILGWSFKINGPAPPLELSSLPQLPGPKKKHTSLITGVSISGFLALCGFLF-GIYMYRRYKNADVIEAWELEIGPHRYSYQELKKATKGFKDKELLGQGGFGSVYKGTLPNSNTQVAVKRISHDSKQGLREFVSEIASIGRLRHRNLVPLLGWCRRRGDLLLVYDFMENGSLDKYLFDGPKTILSWEQRFKVIKDVASALLYLHEGYEQVVIHRDVKASNVLLDGGLNGRLGDFGLARLYEHGANPSTTRVVGTFGYMAPEVPRTGKSTPNSDVFAFGALLLEVACGLRPLEPKALPEDVVLVDCVWNKYKQGRILDLVDPKLNGAFNEREVLMVLKLGILCSNAAPAARPSMRQVVRFLDGEVGLPDELRKPEEVGYQEG----------FDEFMNSLEPSSFY 555          

Query:   39 QFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXI-ATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKE-ELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVI------MLIVFISFYLVRKLKKSD-IIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFD---EPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP 636
             F+  GF  +G KM   G + +  +G+L L N + ++ GHAFY SPL                  + + VP+YP+LG  G AFVL  + +  G   +QYLGL N + +   +    A+EFD +++L+L D+NDNHVG++++S+ S  S P AY+L + +K     +KSG  IQAW+DY+  +  ++V +S     KP   ++S  ++LS +L D+M+ GFSAS GLL + H + GW F +    Q                 + ++    FAV + +      +L V  +F+++R+L+  D I+E  ELE   H+F Y EL  AT  F D  L+G+GGFG+VY+G +  T  +VAVKR++ +S+QG+REF+SEI S+ +L+HRNLV+L GWCR + +LLIVY+Y+PNGSLDK LF+   + K++L WD+R+ II GVA GLLYLHEE E  V+HRD+K  NVL+D +L  +L DFGLA+ YEHG NP TT VVGTLGY+APELTKTGK   +TDV+ +G ++LEVACGR+PIEP+  PEEL+LVDWV E    G     +DP L+ ++D+ EA +V+ LGL C++  PD RP+MR++V++L GE +LP + P
Sbjct:   25 NFVKYGFKQAGLKMD--GASYVRPNGILTLINDSPKILGHAFYPSPLPFKSSKNKSIVATFSTTFVFSIVPKYPELGAQGFAFVLISTNKPKGCLMNQYLGLPNVTSSLEFSTRFLAIEFDGIQNLDLHDMNDNHVGIDISSLISNISRPVAYYLSDHSKNISFSLKSGKPIQAWVDYNEGEMLMNVTVSPFGMPKPYFPLISFPIDLSLVLNDYMYAGFSASNGLLVAEHNIHGWGFKIGEAGQELDKSAVPLIGSSTSTSSKVVHKKDFAVGITLTSATLFILTVIGAFHVLRRLRNGDEILEDWELEFASHKFKYSELHSATGKFGDSNLIGYGGFGKVYRGVIASTGLEVAVKRVAPDSRQGIREFVSEITSMAQLKHRNLVQLHGWCRKKDELLIVYNYVPNGSLDKLLFENEHQKKKLLTWDQRYTIITGVAQGLLYLHEECELQVVHRDVKPSNVLIDEDLQPKLGDFGLARTYEHGINPQTTNVVGTLGYMAPELTKTGKARTSTDVYGYGILILEVACGRKPIEPQKNPEELVLVDWVRELHHQGKISRAIDPSLD-EYDKDEARLVLSLGLFCAHPNPDYRPSMRRIVQFLLGETSLPPLPP 633          

Query:   41 IFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXI-ATVPEYPKLGGHGLAFVLSPSKQLSGSPS-QYLGLLNASENGNSANHIFAVEFDTVKDL-ELGDINDNHVGVNVNSMKSIASTPAAYFLE--NRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSS---ILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTV-----LILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLF--DEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGG 651
            IF GF    ++++L G + I  S LL LTN ++ + GHAFY++P                   + + V      GG GLAF ++PS Q  G+ +  YLGL+N++ +GN +NHIFAVEFDT+    +  D   NHVGVN+N M S  + PAAY  E  ++ KE+  +     +QAWI+YD     L+V ++ LS KPR S   I +  ++L +++++ M+VGFSASTG   SSHY+LGWSF ++G A              ++  T      + + V  A    ++ I+F      R     +++E  E++  PHRF Y++L  AT GF +  L+G GGFG VYKG L  T  +VAVKRI      G+REF +EI S+GRLRH+NLV L GWC  + DLL+VYD++PNGSLD  L+  +    VL W +RF I+KG+++GLLYLHEEWEQ VIHRD+K  N+L+D+ LN RL DFGLA+LY HG    TT VVGT+GY+APELT+TGK + +TDV+AFG VLLEVA G+RP++     ++  LV+WV E++  G  LEVVDPKL+  +DE E  +V+KLGL+C+    D RPTM+QV RYL  +  LP++V          GHG  G
Sbjct:   27 IFEGFDDENSELNLEGSSIIKTSRLLKLTNRSTNIVGHAFYATPFQMLNNTNQPYAYSFSTNFVFSIVSPSSGSGGFGLAFTIAPSTQFPGAEAGHYLGLVNSTNDGNESNHIFAVEFDTMNGYKDDSDTEGNHVGVNINGMDSNITEPAAYIKEGTDKVKEDFRMAKVDAVQAWIEYDGENKTLNVTIAPLS-KPRPSKPIIKNHIIDLYNVMEESMYVGFSASTGQETSSHYLLGWSFAVNGVAPQLKISNLPNPPPKEKEPTSFPWVNIAIGVLSASTFCLLCILFCITCYRRYYMDFEVLEDWEMDC-PHRFRYKDLHLATKGFIESHLIGVGGFGAVYKGVLPSTGAEVAVKRIVRSPFHGMREFAAEIESLGRLRHKNLVNLQGWCNKKNDLLLVYDFIPNGSLDYVLYKPNNNNFVLNWGQRFNILKGISAGLLYLHEEWEQVVIHRDVKTSNILIDAHLNARLGDFGLARLYNHGQLSHTTSVVGTIGYIAPELTRTGKASTSTDVYAFGVVLLEVATGKRPLD----SDQFFLVEWVIEKYHLGQILEVVDPKLDSLYDEEEIELVLKLGLLCTQHRADYRPTMKQVTRYLNFDEPLPDIV--------DWGHGVSG 638          

Query:   15 IAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFE-DFVH-----SYPN 666
            +A+ L  FWVF+ F S  V SQLD+F ++ FHG+GN +SL GVA I  +G+L LTN  +R  G  FY SP+                   A VP+YP LGGHGLAF ++ +K+L G+ P QYLGLLNA++NGNS NH+FAVEFDTV+D E  DI+DNH                                   IQAWIDYD  +++L+V LS  S KP S ILS  VNLSSIL++FM+VGFSASTGLLASSHYVLGW F M+G A+            PK+N+T LI+ V+ A   +I+  V ++FYL+RK+K +D+IEA EL+IGPHRFSYQELKKAT GFRDKEL+GFGGFG+VYKGTL+ +NTQVAVKRISHESKQG+REF+SEIASIGRLRHRNLV+LLGWCR RGDLL+VYDYMPNGSLDK         LG             GL  L+E        R +            G L    LA        PT +  V   G L  E+    +P                      +E KALPEELILVDWVWERW+ GA L+VVDP+L G++DE+E +VV+KLGLMCSN++P  RP+MRQV+RYLEGEVALPE + +P  YD K G    G ++  F  +F+      S+PN
Sbjct:    1 MAEALKLFWVFVFFLSNPVLSQLDEFFYDSFHGAGNNLSLNGVAKIEKNGMLRLTNDVARWFGRGFYPSPIRFKNSSGGKAFSFSTAFAFAIVPQYPTLGGHGLAFAITSTKELPGALPRQYLGLLNATDNGNSTNHVFAVEFDTVQDFEFNDISDNHT----------------------------------IQAWIDYDGQRDQLNVFLSPHSTKPTSPILSCGVNLSSILKEFMYVGFSASTGLLASSHYVLGWRFKMNGVAESLDLSSLPKLPGPKRNNTPLIIGVSVAATSMIVFAVALAFYLIRKIKNADVIEAWELDIGPHRFSYQELKKATRGFRDKELIGFGGFGKVYKGTLRNSNTQVAVKRISHESKQGMREFVSEIASIGRLRHRNLVQLLGWCRRRGDLLLVYDYMPNGSLDK---------LG-----------DFGLAKLYEHGSNPSTTRVV------------GTLGY--LAPELTRTGKPTRSSDVFAFGALLLEVVCGRRP----------------------VEAKALPEELILVDWVWERWREGAILDVVDPRLKGEYDEVEVVVVLKLGLMCSNNSPAVRPSMRQVLRYLEGEVALPEELSAPDAYDKKGGDFISGNDSFHFNLNFIRHPILLSHPN 569          

Query:  116 HGLAFVLSPSKQLSG-SPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLEN-RTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSE-KPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXX--XXXRPKQN---HTVLILCVTFAVVVVIMLIVFISFYLVRKLKKS----DIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWC-RCRGDLLIVYDYMPNGSLDKYLFD-EPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKL--NGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEG------------EVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDV 677
            HG+ F+ +P   + G S SQ+LG LN + +GN  NH+F VEFD  K+ E GDI+DNHVG+NVNS+ SI++  A Y  E+ ++ + L + +G   Q WIDY      ++V +++  + +P+  +LS+ +NLS +  D M+VGF+A+TG L  SH +L WSF+ S  +               PK++       I  +T  V   ++     S++L+R  +      + +E  ELE  PHR ++QE++ AT GF ++ ++G GG G+VYKG L+G   ++AVKRISHE+ QG+REF++EI+S+GRL+HR LV L GWC R  G  ++VYDYM NGSLDK +F+ E  ++L + +R +++K VASG+LYLHE WE  V+HRDIKA NVLLD ++NGRL DFGLA+++ H    +TTRVVGT+GYLAPE+ +TG+ +  TDVF FG ++LEV CGRRP+E         L+DWVWE    G  +  +D +L   G+ DE E   V+ LGL+C+   P ARPTMRQVV+ LEG            +  L E V S   + SK  H  G  +   FEDF  S  +S  +D++  +V
Sbjct:   57 HGIVFLFAPVTGIEGASSSQHLGFLNRTNDGNPDNHVFGVEFDVFKNEEFGDISDNHVGINVNSLTSISAHEAGYCEEDEKSFKRLQLNNGKNYQVWIDY--MDFHINVTMAVAGKTRPQRPLLSVALNLSDVFLDDMYVGFTAATGRLVESHRILAWSFSNSNFSLSSELITSGLPSFVPPKKSIFQSKGFIAGITVGVFFCVVFCSVFSWFLIRWKRLRARRREGMEEWELEYWPHRITHQEIEAATNGFSEENVIGTGGNGKVYKGVLEG-GAEIAVKRISHENDQGMREFVAEISSLGRLKHRCLVSLRGWCKRENGSFMLVYDYMENGSLDKRVFECEESKLLSFKDRIRVLKDVASGVLYLHEGWESKVLHRDIKASNVLLDRDMNGRLGDFGLARMHGHDKVGSTTRVVGTVGYLAPEVIRTGRASAQTDVFGFGVLILEVLCGRRPMEEGKQH----LIDWVWELMMKGELVLALDERLRSRGELDEEEVEKVLHLGLLCTYPDPSARPTMRQVVKILEGGNEVCESEGEEMDAYLLESVRSKSMW-SKYSHTFGRGSHPTFEDFRQSLASS--MDIKASNV 636          

Query:  480 DIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKL--NGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPG 639
            DIKA NVLLD ++NGRL DFGLA+++ H    +TTRVVGT+GYLAPE+ +TG+ +  TDVF FG ++LEV CGRRP+E +  P    L+DW+WE  + G  +  +D +L   G+ DE E   V+ LGL+C+   P ARPTMRQVV+ LEG     EV  S G
Sbjct:  630 DIKASNVLLDKDMNGRLGDFGLARMHGHDKVGSTTRVVGTVGYLAPEVIRTGRASAQTDVFGFGVLILEVLCGRRPME-EGKPH---LIDWLWELMRKGELVLALDERLRSRGELDEEEVEKVLHLGLLCTYPDPSARPTMRQVVKILEGR---NEVCESEG 784          

Query:   39 QFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSG-SPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYF----LENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEK-PRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMS----GEAQXXXXXXXXXXXRPKQNHTV-LILCVTF-AVVVVIMLIVFISFYLVRKLKKSDI---IEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRC-RGDLLIVYDYMPNGSLDKYLFDE--PKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLN--GDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEG 627
            +FIFN F+ +   + L G A I +S LL LTN T+   G A Y S +                   +  P   +L GHG AF+ +P+  + G S SQ+LGL N + +G S NH+FAVEFD  ++ E  DI+DNHVGV+VNS+ S+ S  A Y+     ++   EEL + +G   Q WI+Y    +R++V +     K P   ++S  VNLS +L D M+VGF  +TG L   H +L WSF+ S    G+A            R     +    L V+  + V+++ L V +   LVR+ KK  I   I+  ELE  PHR  Y E+  AT GF +K ++GF   G+VYKG L G   +VAVK I HE++ G++ F++E++S+GRL+HRNLV L GWC+  +GDL++VYDYM NGSL+K +F +     +L W+ER +++K V  G+LYLHE WE TV+HRDIKA NVLLD ++N RL DFGLA+++ HG    TTRVVGTLGY+APE+ +TG+ T+ TDVF FG ++LEV CGR PI+      +  LVDWVW   + G  +  +D +L   G++ E E   V+++GL+C++  P  R  MRQVV+ LEG
Sbjct:  785 EFIFNSFNST--SLLLYGNATIQNS-LLFLTNETTFSIGRALYPSKVPTRSPNSTHLLPFSSSFIFSIPPYKNRLPGHGFAFLFAPTAGMDGVSSSQHLGLFNFTNDGKSTNHVFAVEFDVFENQEFNDIDDNHVGVDVNSLTSLTSHEAGYWSGEDDDDENFEELELNNGENYQVWIEY--MDSRINVTMERAGRKRPDQPLISAVVNLSDVLLDEMYVGFCGATGQLVEGHIILSWSFSQSNFSIGDALETMNLASFVLPRGSVFRSKGFALGVSLGSAVLLVGLGVMLYVALVRRRKKRAIGEEIQEWELEYWPHRIGYSEIYTATDGFSEKNVIGFSSNGKVYKGVLVG-GPEVAVKSIPHENEHGMKAFLAEVSSLGRLKHRNLVGLRGWCKKEKGDLILVYDYMENGSLEKRIFHQYPESMMLSWEERARVLKDVGHGILYLHEGWEATVLHRDIKASNVLLDKDMNARLGDFGLARMHHHGDLANTTRVVGTLGYMAPEVIRTGRATVQTDVFGFGVLVLEVVCGREPIQHN----KPGLVDWVWRLMERGELVLALDERLKARGEYREEEVERVLQIGLLCAHPDPRRRLMMRQVVKALEG 1383          

Query:  355 FRDKELLGFGGFGRVYKGTLQGTNTQVAVK--RISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGD--LLIVYDYMPN-----GSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYE-HGTNPTTTRVVGTLGYLAPEL----TKTGKPTIATDVFAFGAVLLEVACGRRPIEP 558
            F   + +G G +  VYKG        VA+K  R  H   + ++    EI  + RL H N+++L G    R    L +V++YM +      +L    F EP+           ++ + SGL + H      V+HRDIK  N+L+D+    +++DFGLA  ++ H +   T+RVV TL Y  PEL    T  G   ++ D+++ G +L E+  G +PI P
Sbjct:   60 FEKLDKIGQGTYSNVYKGRDVTRGKIVALKKVRFDHLDPESVKFMAREILVLRRLDHPNIIKLEGLVTSRKSFSLYLVFEYMEHDLTGLAALPGCKFTEPQIKC-------YMQQLLSGLDHCHS---HGVLHRDIKGSNLLIDNNGILKIADFGLASFFDPHRSLSMTSRVV-TLWYRPPELLLGATHYG---VSVDLWSAGCILGELYAG-KPIMP 262          

Query:   40 FIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFL-ENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFIS--FYLVRKLKK-SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIR---FEDFVHSYPNS 667
            F +NGF  + N +SL G+A    +GLL LTN T + +GHAFYS P+                   A  P+YP L GHG+AFV++P++ L G+ PSQ+LGL + + NGNS NHI AVE DT+++ ELGDINDNHVG+++N +KS  + PA YF  +N   + L + SG  +Q W+DY++ + ++DV+L+ +S +KP   +LS+  +LS IL + M+VGFS+STG + +SHY+LGWSF M+G+AQ           R         L     V+ V+ ++  +S   YL+R+ KK ++ +E  EL+ GPHRF Y++L  AT GF+DKELLG GGFGRVY+G L  +  ++A                                             +YD  P  +L+   +++  RVL         KGVASGL YLH EWEQ V+HRD                          H                    T+TGK T  TDV+AFGA LLEVACGRRPI P    E+LILVDWV+  W  G  L+  DPKL  D++  E  +V+KLGLMCS+  P+ARP+M QVV+YLE  V LPE         +  G  + G++      F+DF  SYP S
Sbjct:   73 FTYNGFQTAAN-LSLDGLAQFTPNGLLILTNRTKQETGHAFYSHPMRFKNSSNAPAFSFSTTFVFAIHPQYPTLSGHGIAFVIAPTRGLPGALPSQHLGLFSDANNGNSTNHIVAVELDTIQNEELGDINDNHVGIDINGLKSDKAAPAGYFASKNGDFKNLSLISGRPMQVWVDYNALEKQIDVRLAPVSVDKPDIPLLSLPRDLSLILNNTMYVGFSSSTGSVLTSHYLLGWSFKMNGQAQPLAISQLPKLPRIGGQKKSAFLTSGLPVICVVSILAVMSGAVYLIRRKKKFAEELEDWELDYGPHRFKYKDLYFATKGFKDKELLGSGGFGRVYRGVLPTSKLEIAY--------------------------------------------LYD-QPKVTLN---WNQRFRVL---------KGVASGLSYLHGEWEQVVVHRD--------------------------H--------------------TRTGKATTRTDVYAFGAFLLEVACGRRPIAPM---EDLILVDWVFFFWNRGEILQASDPKLGVDYNAEEMELVLKLGLMCSHSEPNARPSMPQVVQYLERTVPLPEF--------TSLGLSANGLSFAHREGFDDFALSYPFS 594          

Query:  111 PKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQN---HTVLI----------------LCVTFAVVVVIMLIVFISFYLVRKLKKSDIIE-----ASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKR--VLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELI-LVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP 636
            P   G GLAF LSP  +  GSP  YLGL+N+S+   + N   AVEFDT  D    D NDNHVG++++S+ S+ +            E + +KSG  I AWI+Y + + +L V LS    KP   +L +D++LS  L++  +VGFSAST      H +  WSF   G               P  N   +TV+I                L + F +   +   + +S +    +KK   +       +++  GP  FSY+ELK AT GF    ++G G FG VYK     T T  AVKR  H S +G  EF++E++ I  LRH+NLV+L GWC  +GDLL+VY++MPNGSLDK L+ E +   +L W  R+ II G+AS L YLH+E EQ VIHRDIK  N++LD   N RL DFGLA+L +H  +P +T   GT+GYLAPE  + GK T  TDVF++G V+LEVACGRRPIE     ++++ LVDWVW  +  G  LE  D +LN +F E E   ++ +GL C+N   + RP+MR+V++ L  E A P +VP
Sbjct:  102 PSSYGDGLAFFLSPENETLGSPGGYLGLVNSSQL--TKNRFVAVEFDTRLDPHFNDPNDNHVGLDIDSLNSMKTADPVL------DENIDLKSGKSITAWIEYKNDQMKLKVFLSSSRSKPERPVLIVDIDLSEYLKELKYVGFSASTEGSTELHLIENWSFKTFGLVPAPPRLHF-----PPHNVSDNTVMIPPPSAVSDSGNKGHKRLGLGFGIAGPVFFCIVLSVFGYVSMKKWRGMRWEKSFKADILAGPREFSYKELKGATKGFHSSRIIGNGAFGTVYKAFFITTGTISAVKRSKH-SHEGKSEFLAELSIIACLRHKNLVQLQGWCVEKGDLLLVYEFMPNGSLDKMLYQESEEGTLLKWSHRYNIIVGMASVLTYLHQECEQQVIHRDIKTSNIMLDGNFNARLGDFGLARLMDHDKSPVSTLTAGTMGYLAPEYLQYGKATEKTDVFSYGVVILEVACGRRPIEKDTDSQKMMNLVDWVWGLYSQGNILEAADKRLNREFKEEEMRKLLLVGLSCANPDCNVRPSMRRVLQILNDE-AEPLLVP 639          

Query:  250 MFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKR-VLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDF--DELE 596
            MF GFS++TG LA SHY+LGW+                             +C +   +V+++++VFIS Y +++LK  D++E  EL+   HRF Y++L KAT GF+D E+LG GGFG VYKG L  T  +VAVK+ISH S+QG+REF+ EIAS+GR+RH++LV L GWC+ + +LL+VYD+MPNGSL   LF+  K  +L W++RF I+KGVAS LLYLHEEWEQ V+HRD+KA NVLLD+++N RL DFGLA+LY+HG    TT +VGTLGY+APEL++TGK T   D+F++GA+LLEVACGR PI+P A  + ++L+DWV E W +G  +E  DPKL+ ++  +E+E
Sbjct:    1 MFAGFSSATGKLAGSHYILGWT-----------------------------VC-SATTLVLLVIVVFISLYYLQRLKYKDVLEEWELQC-SHRFPYRDLFKATKGFKDSEILGSGGFGCVYKGVLPATQEEVAVKKISHNSRQGIREFIMEIASLGRMRHKHLVHLHGWCKHKDELLLVYDFMPNGSLGDILFNHKKSGILSWEQRFSILKGVASALLYLHEEWEQVVVHRDVKANNVLLDADMNARLGDFGLARLYDHGEEACTTHIVGTLGYIAPELSRTGKATTHCDMFSYGALLLEVACGRPPIDPNASSKWVLLLDWVRECWAAGCIVEAADPKLDNEYAVEEME 319          

Query:  325 LKKSDIIEASELEIGP-HRFSYQE-----LKKATMGFRDKE-LLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVR 414
            L  + II +++ E G  H F++ +        AT    D   +LG+ GFG VYKG L  T  ++AVK+ISH S+QG++EF+ EIAS+GR++H++L R
Sbjct:  368 LNGASIITSTDPESGGGHGFAFTDTMYVGFSSATGKLADSHYILGWRGFGCVYKGVLPTTKEEIAVKKISHNSRQGIKEFIMEIASLGRMKHKHLER 464          

Query:  115 GHGLAFVLSPSK-QLSGSPSQY-----LGLLNASENGNS-ANHIFAVEFDTVK-DLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSID--VNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPK---QNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEI----------GPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPS 637
            G GLAF L+P++ QL   PS+      LG+++ S+  N+  N   AVEFDT + D +      +HVG+N+NSMKS+ +   A +L N       I  G    A I Y S    L V L        SSI S+   V+L   L +F  VG SA+TG     H +  W                     PK   +N+  L++ +     VV++ +    FYL RK  +  I + ++ ++          GP +FS+ EL  AT  F + E LG GGFGRVY+G L+  ++ +AVKRIS  SKQG++E+ SE+  I RLRHRNLV+L+GWC  +G+LL+VY++MPN SLD  LF E K +L W  R+KI  G+A  +LYLHEEWEQ V+HRDIK+ NV+LDS+ N +L DFGLA+  +HG    TT + GT+GY+APE   T K +  +DV++FG V+LE+ CGRR +EPKA   ++ LV+WVW+ +  G  LE  DP+L+ DFDE +   ++ +GL C++   + RP++RQ +  L  E +LP ++PS
Sbjct:  137 GDGLAFFLAPNRAQL---PSKMTGGSGLGIVSPSQALNTRKNRFVAVEFDTYRNDWDPRYPIKDHVGININSMKSVKN---AAWLSN-------IPEGQTNHASIKYTSGTKNLSVVLRT-GRGNTSSIQSLYYIVDLRKYLPEFATVGISAATGRYFEIHGIHSW--------------IAEPPNLPKIGDENNKGLVVGLGVCAFVVVVGLGGTVFYLCRKKNEGGIEDDNDFDLAMDHEFEKGTGPRKFSFDELALATSNFSEGEKLGEGGFGRVYRGFLRERSSYIAVKRISRRSKQGMKEYASEVKIISRLRHRNLVQLMGWCHKKGELLMVYEFMPNNSLDSCLF-EAKTLLRWAMRYKIAVGLALAVLYLHEEWEQCVVHRDIKSSNVMLDSDFNAKLGDFGLARFVDHGKGSQTTVLAGTMGYMAPECFMTSKASKESDVYSFGVVVLEICCGRRSVEPKAKENQIRLVEWVWDLYGVGKLLEAADPRLSADFDEQQMKRLMTVGLWCAHPDCNLRPSIRQAINVLNFEASLP-ILPS 652          

Query:  377 TNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFD--EPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP 636
            T  +VA+KR++H+S+QG++EF++EI S+GRLRHRNLV+L GWCR + +L++VYDY+PNGSLDK LFD  + K++L W++R+KI+ GV+  LLYLHEE +Q V+HRD+K  NVL+D+ELN RL DFGLA++Y+HG NP TT +VGTLGYLAPELT+ GK T + DV+A+G ++LEVA GRRPIEP+   +EL+L+DWV E    G  L V+DP L+ +++  EA +V+ LGL+CS+  PD RP +R+V++YL  +V LPE+ P
Sbjct:  251 TGLEVAIKRVAHDSRQGMKEFVAEIISMGRLRHRNLVQLHGWCRRQDELILVYDYVPNGSLDKILFDDQQKKKILTWEQRYKILIGVSQALLYLHEECDQRVVHRDVKPSNVLIDAELNARLGDFGLARMYKHGNNPETTHIVGTLGYLAPELTRIGKATTSIDVYAYGVLMLEVATGRRPIEPQRNAQELVLMDWVRELHSRGEILSVIDPTLD-EYNPDEAKLVLSLGLLCSHPHPDYRPDIRRVIQYLLKDVCLPELPP 511          

Query:   40 FIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXX--XXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEA 278
            F++NGF  +   +SL G + +  +G+L LTN + R+ GHAFY SP+                     +  P+YP LGGHGLAFVL  +K   G  P+QYLGL N + N + +  + AVEFD V++LEL DINDNHVG++++S+ S                           AWI+Y+S +  ++V +S L   K    ++S  ++LS +L ++M++GFSASTGLL ++H V GWSF + G A
Sbjct:   22 FVYNGFLKA--DLSLDGASQLRSNGILSLTNDSVRLIGHAFYPSPIHFKRSKDHRSWVVTFSTNFVFSMAPKYPGLGGHGLAFVLLSTKAPMGCLPNQYLGLPNVTSNADFSTRVLAVEFDAVQNLELMDINDNHVGIDISSLIS--------------------------NAWIEYNSQEQLMNVTISPLGIPKSFRPLISFPIDLSMVLNEYMYIGFSASTGLLTAAHNVHGWSFRIGGRA 236          

Query:   40 FIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGSPS-QYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLEN----------------RTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLL-----SEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVD 585
            F+FNGF+ S   M L GVADI +S  L LTN T    G A Y S +                   +  P    + GHG+ F+ +P   + G+ S Q LG LN + NGNS NH+F VEFD  ++ E  DI++NHVG+NVNS+ S+++  A Y+ +N                ++ + L + +G   Q WIDY      LD+ L++        +P+  +LS+ +NLS +  D M+VGF+A+TG L  SH +L WSF+ S  +                   ++ + V F VV   +   F+  +   + ++ + +E  ELE  PHR ++QE++ AT GF ++ ++G GG G+VYKG L+G   ++A            R F  E + I   + R                                             +++K VASG+LYLHE WE  V+HRDIKA NVLLD ++NGRL DFGLA+++ H    +TTRVVGT+GYLAPE+ +TG+ +  TDVF FG ++LEV CGRRP+E +  P    L+DW+WE  + G   + ++
Sbjct:   26 FVFNGFNSS--DMLLYGVADI-ESRFLTLTNHTRFAIGRALYPSKVPAKSPNSSHVVPFSTSFIFSMAPYKDMIPGHGIVFLFAPVTGIEGTTSAQNLGFLNHTNNGNSINHVFGVEFDVFQNEEFDDISNNHVGINVNSLTSMSAHEAGYWPDNGKISSGGGNSSSEEDEKSFKRLQLNNGKNYQVWIDY------LDLHLNVTMAEAGKTRPQRPLLSVALNLSDVFLDDMYVGFTAATGRLVESHRILAWSFSNSNFSLSS---------------ELITMGVFFCVVFCSVFSWFLIRWKRLRARRREGMEEWELEYWPHRITHQEIEAATNGFSEENVIGTGGNGKVYKGVLEG-GAEIA------------RVFECEESQILSFKDR--------------------------------------------IRVLKDVASGVLYLHEGWESRVLHRDIKASNVLLDKDMNGRLGDFGLARMHGHDKVGSTTRVVGTVGYLAPEVIRTGRASAQTDVFGFGVLILEVLCGRRPME-EGKPH---LIDWLWELMRKGELCQTIN 508          

Query:  115 GHGLAFVLSPSKQLS-GSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKE------ELIIKSGAKIQAWIDYDSAKNRLDVKL-SLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMS-----GEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLK-KSD---IIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLF-DEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP 636
            G G AF+++P   L  GS  +YLGL N++ +GN  NH+ AVE DT K  +  D NDNH+G+++NS++S           NRT        ++          W++YD     +DV +    + +P   ++S  V L  I++ + ++GF+ASTG     + VL W+  +      G+A+                  V++     A+VVV++  VF+ +Y+ +K + KSD   +     L   P  F +++LKKAT  F +K  LG GGFG VYKG L   +  VAVK+ S + K G  +F++E+  I RLRH++LV LLGWC   G LL+VYDYMPNGSLDK LF     R L W  R+KII GVAS L YLH E++Q                 L G                     V GT+GY+APE   TGK T  +DV+ FGAVLLEV C +RP    A      LVDWVW   + G  +E VD +L  D+   EA  ++ LGL CS+     RP  + +V+ L G V++P V P
Sbjct:  112 GEGFAFIIAPDLNLPPGSDGEYLGLTNSTTDGNPNNHLIAVELDTFK--QDFDSNDNHIGLDINSIRS-----------NRTVSLSDLGIQIAPLDPKNYSVWVEYDGENKVMDVYMVEEGNPRPAEPVMSAKVELREIVKQYSYMGFAASTGNATQLNCVLQWNLTVELLEEDGDAEWV---------------KVVLGAGVPAIVVVLIACVFLWYYVQKKRRAKSDPNILGTLRSLPGTPREFEFKDLKKATNNFDEKLKLGEGGFGVVYKGLLPKEHVHVAVKKFSRDVK-GKDDFLAELTIINRLRHKHLVPLLGWCHKNGMLLLVYDYMPNGSLDKQLFCGREMRTLEWSVRYKIIAGVASALHYLHNEYDQ----------------RLEG---------------------VPGTMGYIAPECFHTGKATPESDVYGFGAVLLEVVCAQRPWASDATFH--FLVDWVWCLHREGRIVEAVDERLGNDYVVEEAQRLLLLGLACSHPIATERPKTQAIVQVLSGSVSVPYVPP 583          

Query:   15 IAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLD--------VEDRDVDIEA 681
            +AK+L+FFWVFLV  S  VFSQLDQFIFNGFH +GN MSLTGVADI   GL+CLTNT+SRVSGHAFYSSP+                   A VPEYPKLGGHGLAF LSPSK+LSG PSQYLGLLNA++NGNS NHIFAVEFDTVKDLE GDI+DNHVG+N+NSM S AS  AAYFLEN TK+EL +KSG  IQAWIDYDSA+NRL+VKLS  SEKPRSSILS DV+LS ILQD MFVGFSASTGLLASSHYVLGWSFNMSGEA+           RPK+NHTVLILCVTF+ V+++M I+FISFYLVRKLK +DIIEA EL+IGPHRFSY+ELKKAT GFRDKELLGFGGFGRVYKGTL  TNTQVAVKRISHESKQGLREF+SEIASIGRLRHRNLV+LLGWCRCRGDLL+VYD+MPNGSLDKYLFDEPKRVL W+ERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRL DFGLAKLYEHG NP+TTRVVGTLGYLAPELT+TGKPT ++DVFAFGA LLEV CGR+PIEPKALPEELILVDWVWERWQSGA LEVVDPKLNG+FDELEAIVVIKLGLMCSNDA +ARPT+RQVVRYL GEVALPEVVPSPGG DS+KG+G  G     FED+VHSYP+S Y D         EDRDVDIEA
Sbjct:    1 MAKKLVFFWVFLV-CSDQVFSQLDQFIFNGFHEAGNNMSLTGVADIGSKGLICLTNTSSRVSGHAFYSSPVRFKNSSSSKVFSFSTAFAFAMVPEYPKLGGHGLAFTLSPSKELSGFPSQYLGLLNATDNGNSTNHIFAVEFDTVKDLEFGDIDDNHVGINLNSMVSNASASAAYFLENSTKQELSLKSGRMIQAWIDYDSARNRLEVKLSPFSEKPRSSILSFDVDLSPILQDSMFVGFSASTGLLASSHYVLGWSFNMSGEAESLSLLSLPSLPRPKENHTVLILCVTFSAVLIMMSIIFISFYLVRKLKNADIIEAWELDIGPHRFSYRELKKATRGFRDKELLGFGGFGRVYKGTLPSTNTQVAVKRISHESKQGLREFVSEIASIGRLRHRNLVQLLGWCRCRGDLLLVYDFMPNGSLDKYLFDEPKRVLSWEERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLGDFGLAKLYEHGQNPSTTRVVGTLGYLAPELTRTGKPTTSSDVFAFGAFLLEVVCGRKPIEPKALPEELILVDWVWERWQSGAVLEVVDPKLNGEFDELEAIVVIKLGLMCSNDALEARPTIRQVVRYLAGEVALPEVVPSPGGSDSRKGNGRRGAG---FEDYVHSYPDSSYFDKGSACSSAFEDRDVDIEA 671          

Query:   36 QLDQFIFNGFHG-SGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPY 669
            Q  +  F GF   + N ++LTG+A I  +G+LC+TN TSR+ GHAFYSSP                   +A VPEYPKLGGHGLAF ++ SK L   PSQYLG+LNA++ GN +NH+ AVEFDTV+D E  DINDNH+G+++NS+ S AS PA+Y+ +  TK+ L +KSG  IQAWIDYDS ++ ++V ++  S +PR  ILS  V+LS  LQ+FM+VGFSASTGLLASSHY+LGWSF ++G+AQ            P +  T L + V+ + V+ +++ + I+ Y + K+K +D+IE  ELEIGP R+ YQELK+AT GF DK LLG GGFGRVYKGTL    T+VAVKRISHESKQGLREF+SEIASIGRLRHRNLV+LLGWCR RGDLL+VYD+M NGSLDK+LFDEP+ +L W++RF+IIKGVASGLLYLHE +EQ V+HRD+KA NVLLD E+NGRL DFGLA+LYEHG+NP TTRVVGTLGYLAPEL KTGK T ++DV+AFGA+LLEVACGRRP+EPKALPEEL+LVDWVWE+++ G  LE+VD +LNG +D+ E ++V+KLGL+CSND P ARP+MRQV+R+L+GE  LPE +  PG +D  K    G      FE FVHS  +S +
Sbjct:   22 QPTELYFPGFKDINPNNLTLTGIAQIEKNGILCVTNDTSRLIGHAFYSSPFRFKNSSNGQAFSFSTSFALAIVPEYPKLGGHGLAFTITASKDLKALPSQYLGILNATDMGNFSNHLVAVEFDTVQDFEFQDINDNHIGIDLNSLDSNASAPASYYTDGSTKQNLTLKSGKPIQAWIDYDSVEHVINVTIAPNSTRPRLPILSFHVDLSPYLQEFMYVGFSASTGLLASSHYILGWSFKINGQAQALDLSSLPLLPGPPKKDTALTVGVSVSSVIFVIIALSIAIYFIIKIKNADVIEDWELEIGPQRYPYQELKQATNGFSDKTLLGHGGFGRVYKGTLPNAKTEVAVKRISHESKQGLREFLSEIASIGRLRHRNLVQLLGWCRRRGDLLLVYDFMANGSLDKFLFDEPQTILSWEQRFRIIKGVASGLLYLHEGYEQIVVHRDVKASNVLLDDEMNGRLGDFGLARLYEHGSNPGTTRVVGTLGYLAPELPKTGKATTSSDVYAFGALLLEVACGRRPLEPKALPEELVLVDWVWEKFRQGMVLEMVDTRLNGQYDQGEMLMVLKLGLICSNDVPVARPSMRQVLRFLDGEAELPENLRPPGAFDGGKAFAEG------FEAFVHSLASSSF 650          

Query:   40 FIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLE-NRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFIS---FYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIR---FEDFVHSYPNSPY 669
            FI+NGF  S  K+SL G+A    +GLL LTN T R  G AFY +P+                   A + EYP L GHG+AFV++P++ L G+ PSQ+LGL N S NGN+ANH+ AVE DT++  E  DIN+NHVG+++N +KS  S PA Y+ +  R    L + SG ++Q W++Y   + R+DV L+ ++  KP++ +LS+  +LSSIL + M+VGFS+STG + +SHYVLGWSF ++G+AQ           R  +      L +   +++V  ++  +S   +++ RK K ++++E  ELE GPHRF Y++L  AT GF+DKEL+G GGFGRVY+G L  +  ++AVKR+SHES+QG++EF++EI SIGRLRHRNLV+LLG+CR +G+LL+VYDYMPNGSLDKYL+D+P   L W +RF++IKGVASGL YLHEEW+Q VIHRD+KA NVLLD ELNGRL DFGLA+LY+HG +P TTR+VGTLGYLAPE T+TGK T  TDVFAFGA LLEVACGRRPI+ ++  E++IL+DWV+  W  G  LE  DPKL  D+   E  +V+KLGL+CS+  P+ARPTMRQ V++LEG++ LPE+        S     SGG+       F+DF  SY +S Y
Sbjct:   23 FIYNGFRSS--KLSLDGIAKFTSNGLLKLTNETWRQKGQAFYPNPVNFKNSTNGSVFSFATTFVFAIISEYPNLSGHGIAFVIAPTRGLPGTLPSQFLGLFNDSNNGNAANHVVAVELDTIQSNEFADINENHVGIDINGLKSDKSFPAGYYEDGTRQFRNLTLISGQRMQVWVEYHGLEKRMDVTLAPINVPKPKTPLLSLSRDLSSILNNEMYVGFSSSTGSVLTSHYVLGWSFKINGQAQELTLSQLPKLPRLGRKKRSRFLTIGLPLILVSSVLAAVSGVAYFIRRKRKFAEVVEDWELEYGPHRFKYKDLYVATKGFKDKELVGAGGFGRVYRGVLPTSKLEIAVKRVSHESRQGMKEFVAEIVSIGRLRHRNLVQLLGYCRRKGELLLVYDYMPNGSLDKYLYDQPNVTLNWRQRFRVIKGVASGLFYLHEEWDQVVIHRDVKASNVLLDGELNGRLGDFGLARLYDHGKDPQTTRIVGTLGYLAPEHTRTGKATPLTDVFAFGAFLLEVACGRRPIQAQSPTEDVILIDWVYSCWYKGDILEAKDPKLGTDYVAEEVELVLKLGLLCSHSEPEARPTMRQCVQFLEGDIPLPEI--------SSLTLSSGGLAFAHREGFDDFAMSYTSSIY 651          

Query:   40 FIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLE-NRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXR--PKQNHTVLILCVTFAVVVVIMLIVF-ISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKK-GHGSGGINTIRFEDFVHSYPNSPY 669
             I NGF  S   +SL G+A+   +GLL LTN T +  GHAFY +P+                   A +PEYP L GHG+AFV++P++ L G+ PSQ+LGL N S NGN+ NH+ AVE DT++  E  DINDNHVG+++N +KS  S PA Y+ +  R    L + SG ++Q W++Y   + R+DV L+ ++  KP++ +LS+  +LSSIL + M+VGFS+STG + +SHYVLGWSF+++G+AQ           R  PK+    L + +   +V +++  V  +++++ RK K ++++E  ELE GPHRF Y++L  AT GF+DKELLG GGFGRVY+G L  +  ++AVKR+SHES+QG++EF++EI SIGRLRHRNLV+LLG+CR +G+LL+VYDYMPNGSLDKYL+D+P   L W +RF++IKGVASGL YLHEEW+Q VIHRD+KA NVLLD ELNGRL DFGLA+LY+HG +P TT +VGTLGYLAPE T+TGK T   DVFAFGA LLEVACGRRPI+ ++  E++IL+DWV+  W  G  LE  DPKL  ++   E  +V+KLGL+CS+  P+ARPTMRQ V++LEG++ LPE+             H  G      F+DF  SY +S Y
Sbjct:   23 LISNGFRSS--NLSLDGIAEFTSNGLLKLTNETRQQKGHAFYPNPVNFKNSTNGSVFTFSTTFVFAIIPEYPNLSGHGIAFVIAPTRGLPGALPSQFLGLFNESNNGNATNHVVAVELDTIQSNEFADINDNHVGIDINGLKSDKSFPAGYYEDGTRQFRNLTLISGQRMQVWVEYHGLEKRMDVTLAPINVPKPKTPLLSLSRDLSSILNNEMYVGFSSSTGSVLTSHYVLGWSFSINGQAQELTLSQLPKLPRLGPKKRSRFLTIGLPLILVSLVLAAVSGVAYFMRRKRKFAEVVEDWELEYGPHRFKYKDLYVATKGFKDKELLGAGGFGRVYRGVLPTSKLEIAVKRVSHESRQGMKEFVAEIVSIGRLRHRNLVQLLGYCRRKGELLLVYDYMPNGSLDKYLYDQPNVTLNWRQRFRVIKGVASGLFYLHEEWDQVVIHRDVKASNVLLDGELNGRLGDFGLARLYDHGKDPQTTHIVGTLGYLAPEHTRTGKATPLNDVFAFGAFLLEVACGRRPIQAQSPAEDVILIDWVYSCWYKGDILEAKDPKLGTEYVAEEVELVLKLGLLCSHSEPEARPTMRQCVQFLEGDIPLPEISSLTLSSSGLAFAHREG------FDDFAMSYTSSIY 651          

Query:   38 DQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXX--IATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFL-ENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLS-LLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXX----XRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEV 634
            DQFI+NGF G+   + L G A I  +G+L LTNT+ +++ HAFY SP+                    IA VPE+    GHG+ FV+SPS   S +  SQYLGL N + NGNS+NHIFAVEFDT+   E  D NDNHVG++VN +KSI S PAAYF  E R    L + SG  IQ W+DY+  +  L+V L+ + S KP   +LS  V+LS IL D M+VGFSA+TG +AS+HY+LGWSFN SG+A+               R K +  +LI+        ++++I+  + Y  R+ K  ++ EA E E GP RFSY+ L KAT GFRDK+L+G GGFG+VYKGTL  +N Q+AVK++SHES QG++EF+SEI S+GRLRH+NLV LLG+CR + +LL+VYDYMPNGSLD++LFD+    L W +RF+II+GVAS L YLHEEWEQ V+HRDIKAGNVLLDS LNGRL DFGLA+ Y+H   P TT +VGTLGYL PE+T+TGK T ++DVFAFGA LLEVACGR+PI+P   PEE+ LV+ V   W+ G  L+  DP+L G++   E + V+KLGL+CS+  PD RPT+++VV+YL+G  +LP++
Sbjct:   28 DQFIYNGFVGA--NLHLDGNAKIHHNGILQLTNTSKQLAAHAFYPSPIKFNTSSPSTVRSLSFSTNFVIAMVPEWKDTSGHGIVFVISPSMDFSHAVESQYLGLFNTTNNGNSSNHIFAVEFDTILSPEFEDRNDNHVGIDVNGLKSIQSEPAAYFSNEERKNRSLKLISGHPIQVWVDYNDGEKLLNVTLAPMRSPKPDQPLLSTSVDLSDILLDTMYVGFSAATGSIASNHYILGWSFNRSGQARSLEISELPKLPKVGRRIKPDRLILIIAAG-----LLLVIITGATYFYRRKKYEEVYEAWEQEYGPQRFSYKTLYKATQGFRDKQLVGAGGFGKVYKGTLPSSNEQIAVKKVSHESNQGMKEFVSEIVSMGRLRHKNLVPLLGYCRRKKELLLVYDYMPNGSLDQFLFDDDHPNLNWPQRFQIIRGVASALRYLHEEWEQVVLHRDIKAGNVLLDSNLNGRLGDFGLARFYDHDAGPQTTCLVGTLGYLDPEITRTGKATKSSDVFAFGAFLLEVACGRKPIDPHLPPEEIFLVELVNRCWKRGIILDASDPRLQGNYVVEEMVKVLKLGLLCSDPRPDRRPTIKEVVQYLDGNASLPDI 626          

Query:   17 KELIFFWVFLVFSSGHVFSQ-LDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXX--XIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLL-SEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFIS--FYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEV 634
            K L+    F +F +     Q  +QFIFNGF G+   + L G+A I  +GLL LTNT++   G AF+  PL                     A VPE    GGHG+AF +SP+ +L+G+  SQY GL N+S  G SANH+FA+E DT +  E GD+  +HVG++VN+++S+ S PA YF E  TK  L   SG+ +Q WID+D  +  L+V L+ + S KP   +LS  ++LS++L D M+VGFS+STG LAS HY+LGWSF   G+AQ             ++  +   L +    V VI ++V IS   Y++R+ K  +I E  E E GP RFSY++L KAT GF+++ELLG GGFG VY+G L  +N  +AVK+ISH+SKQG+++F+SEI S+GRLRHRNLV+LLG+CR +G+LL+VYD MPNGSLDK+LF   K  L W +RF+I+K +AS LLYLHEEWEQ V+HRD+KA N+LLD+  NGRL DFGLAKLY+HGTNP TT VVGTLGY+APEL +TGK T +TDVFAFG  +LE+ACGR+P+E +  PE  IL DWV + W++GA L+  D +L G++   E  +V++LGL+C+N     RP+MRQ+V+YL+G V LPE+
Sbjct:    6 KSLLILVTFFMFLNRFALPQEQNQFIFNGFKGA--NLHLNGIAKILPNGLLELTNTSNIQVGRAFFPFPLKFNKSSSNSSDSLSFSTNFVFAMVPELANPGGHGIAFTISPTMELAGAVASQYFGLFNSSSTGLSANHVFAIELDTNQSPEFGDMEGSHVGIDVNNLRSLKSAPATYFTEGITKS-LDFLSGSPMQLWIDHDEVEKLLNVTLAPVGSNKPSQPLLSTSIDLSTVLLDSMYVGFSSSTGELASDHYILGWSFRKFGKAQSLDYSKLPSLPPRRKPKSKADLIIILPSVAVIAMLVAISGGAYVIRRKKYEEIREDWEKEYGPQRFSYKDLYKATKGFKERELLGRGGFGSVYRGVLPSSNEHIAVKKISHDSKQGMKQFVSEIVSMGRLRHRNLVQLLGYCRRKGELLLVYDCMPNGSLDKFLFSNSKPNLSWVQRFRILKDIASALLYLHEEWEQLVLHRDVKASNILLDANFNGRLGDFGLAKLYDHGTNPQTTCVVGTLGYMAPELARTGKATTSTDVFAFGTFMLEIACGRKPLELQLDPEGTILADWVLQLWKAGAILDASDHRLEGEYVAEEMELVLRLGLLCTNPRASNRPSMRQLVQYLDGNVTLPEI 627          

Query:   38 DQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXX--XIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEE-LIIKSGAKIQAWIDYDSAKNRLDVKLS-LLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFI--SFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVV 635
            +QFI  GFH +   + L G+A I  +GLL LTN++ +  G AF+  P+                     A VPE+PKLGGHGLAF +SPS +L+G+  SQY GL N   NG S NH+FA+E DT+K  E  DI+ NHVG++VN++ S AS PA Y+ E   K + L + SG  IQ WIDYD  +  L V L+ L ++KPR  +LS  ++LS +   +M+VGFSASTG ++S+ Y+LGWSFN SG+AQ             +     +   +   ++++ +L++F   + Y   + K  +I E  E E GP RF Y++L KAT GF+++ELLG GGFG VY+G L  ++ QVA+KR+SH SKQG++EF++EIAS+GRLRHRNLV+LLG+CR +G+LL+VYD+MPNGSLDK+LF   K  L W +RF+I+KGVAS LLYLHE+W+Q VIHRDIKA N+LLD+ LNGRL DFGLAK +EHG  P TT VVGT+GY+APEL +TG+ T ++DVFAFG ++LE+ACGRR +EP+  PEE+ILVDWV + W++   L+  DP+L G++   E  +V+KLGL+C++ AP +RP+M  VV+YL G  +LPE++
Sbjct:   27 NQFIHEGFHEA--NLHLNGIAKIHPNGLLELTNSSYQQIGRAFFPLPIKFNTSSSNNSGSLSFSSSFVFAMVPEFPKLGGHGLAFTISPSMELTGAVASQYFGLFNTRTNGRSTNHVFAIELDTIKSPEFEDIDANHVGIDVNNLLSNASAPATYYSETEGKNKTLELISGKPIQVWIDYDEREMLLQVTLAPLRTKKPRRPLLSAKLDLSQVFLKYMYVGFSASTGAMSSNQYILGWSFNKSGQAQSLDYSKLPSPPHRRYPAKKVDFRIMVPLLIMSLLVIFFIGAAYKTWRKKYEEIREDWEQEYGPQRFCYRDLYKATNGFKERELLGVGGFGEVYRGALPSSHEQVAIKRVSHNSKQGMKEFVAEIASMGRLRHRNLVQLLGYCRRKGELLLVYDFMPNGSLDKFLFSNEKPNLNWVQRFQILKGVASALLYLHEQWDQVVIHRDIKASNILLDALLNGRLGDFGLAKFHEHGATPQTTHVVGTVGYIAPELARTGQATTSSDVFAFGNLMLEIACGRRTLEPERPPEEIILVDWVLQFWKTDLILQTNDPRLEGNYVVTEMELVLKLGLLCAHPAPASRPSMSTVVQYLNGSASLPELL 629          

Query:   40 FIFNGFH-----GSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQ-LSG---SPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXX-----XXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKK-SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPE 633
            FIFNGF      G    + L GVA+++D GL  LTNT S   GHAFYS P                    A VPE     GHG+AFVL+PS++ +SG   +  Q+LGL N + NGN +NHI AVE DT  + E GD N NHVG+++NS+ S+  T A    E+   + + + SG   Q W++YD AK++L+V LS  +      +LS+D++LS  + D M+VGFS++T  L +S YVLGWSF + G+A+                R  +  T L + ++ A V+ + +IV + F L RK     +++E  E + GPHRF+Y++L  AT GF +KELLG GGFG+V++G L G+  Q+AVKRI H+S+QG++EF++EI +IGRLRH NL RLLG+CR + +LL+VYD+MPNGSLDK+L+++PK  L W++RF IIK VA+ L YLHE W + +IHRDIKA NVLLD E NG+L DFGLA+  +   +P TT V GT GY+APEL KTGK + +TDV+AFGA  LEV CGRRPI+ +A  EE+ LVDWV++ W+ G  L+  D KL  DF   E  +V+KLGL+CS++    RP M QV+ YL G+ +LPE
Sbjct:   75 FIFNGFSSGLVSGQNKSLELAGVAEVSD-GLCRLTNTESFKIGHAFYSVPFRFKNSSNTNAFSFSTTFVFAMVPE--NFRGHGMAFVLAPSQEFISGQGVASGQHLGLFNRTNNGNPSNHIVAVELDTFLNQEFGDPNGNHVGIDINSLSSVNLTSANDVPESGLLDPVDLVSGEGGQLWVEYDGAKHQLNVTLSRFNTSKPEPLLSVDIDLSPFILDQMYVGFSSATAQLTASSYVLGWSFQIDGKAEDLDLAKLPSVPSASIERSGKKKTTLAVGLSIAGVLFVGVIVSVIFILKRKKDTFVELVEDWEFQFGPHRFAYKDLFIATRGFNEKELLGQGGFGQVFRGELPGSKVQIAVKRIFHKSQQGMKEFIAEIGTIGRLRHPNLARLLGYCRSKDELLLVYDFMPNGSLDKFLYNKPKATLNWNQRFSIIKDVATALAYLHEGWAEVIIHRDIKASNVLLDGEFNGKLGDFGLARCSKLAQDPQTTHVAGTFGYMAPELAKTGKASTSTDVYAFGAFCLEVTCGRRPIKQRASAEEVHLVDWVFKCWKEGDILKTADSKLENDFKVGETDLVLKLGLLCSHNVAAHRPRMSQVILYLRGQASLPE 680          

Query:   19 LIFFWVFL-VFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXX----XXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGSPS-QYLGLLNASENGNSANHIFAVEFDTVKDL-ELGDINDNHVGVNVNSMKSIASTPAAYFLENRT-KEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQ------NHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKR-VLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEV 634
            LIF  VF  VF+      Q   FIFN F+GS +K++L G + I  SG L LTN ++   GHAFYS  +                       A VP     GGHGLAF LSPSKQ  G+ +  Y+G+ N   +G S+NH+FAVEFDTV    +  D + NHVG+N+NSM S  + PAAYF+ N   KE++ ++SG  + AWI+YD   N ++V +S L  EKP   ++S  ++L+ ++++ M+VGFSASTG  +SSH++LGWSF+  G A+            PK+      +  V+ L    + V V++L + I F L ++  KS+ +E  EL+  PHRF Y++L  AT GF+D E++G GGFG VYKG L  T  ++AVK+I+  S QGLREF +EI S+GRLRH+NLV L GWC+ + DLL++Y+Y+P GSL   LF++ +   L WD+RF IIKG+A+GLLYLHEEWE  VIHRD+K+ NVL+D+ +N RL DFGLA+LY+HGT   TT +VGT+GY+APEL + GK +  +DVFA+G +LLEV  GR+PI+ +     + LVDWV E  ++G  L+ +DPKLN  F   E  +V+ LGL+CS+  P+ RP+MR+V+RYL  +  LP +
Sbjct:   10 LIFCIVFFPVFAQ----PQPPSFIFNDFNGSESKLTLEGASIIRASGALKLTNKSNYAVGHAFYSESIQMLDNKSLPGSPKASSFSTTFVFAIVPPTSGRGGHGLAFTLSPSKQFPGAEAGHYMGIFNKENDGLSSNHVFAVEFDTVNGFNDDSDSDGNHVGININSMYSKETEPAAYFINNTNLKEDMKLESGDPVHAWIEYDG--NFVNVTISPLKVEKPSQPLISHRIDLTPLVEETMYVGFSASTGEKSSSHFILGWSFSTGGTARQLNVSQLPVPP-PKEKDGSSFDPQVIGLIAALSTVTVLLLGILIYFTLYKRKAKSEELEDWELDC-PHRFQYKDLYAATRGFKDSEIIGVGGFGAVYKGVLPTTGAEIAVKKITQNSIQGLREFAAEIESLGRLRHKNLVNLQGWCKQKNDLLLIYEYIPYGSLHSLLFNQKQGFALSWDQRFNIIKGIAAGLLYLHEEWELVVIHRDVKSSNVLIDAGMNARLGDFGLARLYDHGTESHTTNIVGTIGYIAPELARNGKASTRSDVFAYGVLLLEVVSGRKPIDSR----NIFLVDWVIECHKAGQILDAMDPKLNSSFVTEEVRLVLLLGLLCSHPKPEVRPSMRKVMRYLNRDDPLPPI 629          

Query:   40 FIFNGFH-----GSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSG-SPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTK-EELIIKSGAKIQAWIDYDSAKNRLDVKLS--LLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXX----XXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFIS-FYLVRKLKK-SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPE 633
            FIFNGF      G    + L G+A++   GL  LT++++   GH FYS P                      VPE  +  GHG+ FVL+PSK+    +P Q+LGL N S +G S+NHI A+EFDT ++ E  DI+DNHVGV++NS+KS  S  A Y      K     +  G ++Q W++YD  K++L+V LS  +   KP+  +LS+D++LS I+ + M++GFS++TGL  +S Y+ GWSF M G A+               +  +   +++      V V+++ +VF + F+L RK  + ++I+E  E++ GPHRF Y++L  AT GF +KELLG GG G+VY+G L  +  Q+AVKRI  +S+Q ++EF++EI +IGRLRH NLVRLLG+CR + +LL+VYDYMPNGSLDKYL ++P+  L W +RFKIIK VAS + YLHEEW + +IHRDIKA NVLLD +LNG+L DFGLA+  +H     T  + GT GY+APEL KTG+   +TDV+AFGA  LEV CGRRP+ P+A  EE+ LVDWV+  W  G  L+  DP+LN DF   E  +V+KL L+CS+     RP M QV+ YL G+ +LPE
Sbjct:   23 FIFNGFSLQLVSGQEQSLELGGIAELRTDGLFRLTDSSTFQVGHVFYSVPFKFKSSPNANAFSFSTTFVFVIVPENSR--GHGITFVLAPSKEFGQVAPGQHLGLFNFSTDGLSSNHIVAIEFDTFQNQEFADIDDNHVGVDINSLKSAKSVSAGYVYSKTGKYRPADLSCGDRMQVWVEYDGTKHQLNVTLSPVIRRSKPKVPLLSMDIDLSPIILEQMYIGFSSATGLQVASTYISGWSFQMDGVAKDLDLDKLPSVTRSRKKKSRKKQIIVAVAVPVVGVLLLAVVFSAIFFLSRKKDRFTEILEDWEVQFGPHRFPYRDLFAATGGFNEKELLGRGGCGQVYRGELPASKVQIAVKRIFDKSQQRMKEFLAEIGTIGRLRHPNLVRLLGYCRGKDELLLVYDYMPNGSLDKYLHNKPEVTLNWSQRFKIIKDVASAVAYLHEEWLEVIIHRDIKASNVLLDDDLNGKLGDFGLARCSKHAQE--TIHLAGTYGYIAPELAKTGRANTSTDVYAFGAFCLEVVCGRRPLMPRASAEEVHLVDWVFNCWNEGDILKTADPELNKDFAAEEIDLVLKLALLCSHTIAAYRPRMSQVISYLNGQASLPE 627          

Query:   39 QFIFNGFHG--------SGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSS-ILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSG-EAQXXXXXXXXXXXRPK---QNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGT--NTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDE--PKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPY 669
            +F ++GF          +   ++L GV ++   G+L LTN TSR+ GHAFY SPL                   A VPEYPKLGGHGLAFV++P  +L G+ PSQYLGLL+A++ GN+ NH+ AVEFDTV+D E GDINDNHVGV++NS+ S AS  AA          + +KSG  I AW+DYD     L+V ++  S    +S ++S  V+LS I  D MFVGFSASTGLLASSHY++GWSF + G  A            RP    +N T  IL   F+  V ++ +   + Y   + K  D++E  EL+ GPHR+SY EL++AT GFRD+ELLG GGFG+VY+G L G    T VAVKR+SHES+QGLREF++EIASIGRLRHRNLV+L GWCR RGDLL+VYDYMPNGSLDK+LF +      L W  R K+++ VA+ LLYLHE WE+ V+HRD+KA NVLLD +++GRL DFGLAKL+EHG NP+TTRVVGTLGYLAPELT+TGK T A DVFAFGA+ LEV  GRRPIEP+A PEEL+L +W WER+ +G    VVD +L G+FD  EA   +K+ L CS+ AP  RPTMR+V RYL+   A     P P         G  G     + DFVHSYP S Y
Sbjct:   22 EFTYSGFRNGGGGGGAGNSPNLTLNGVTELRPDGILRLTNETSRLIGHAFYPSPLRLLAGGAAVSFSTEFA--FAVVPEYPKLGGHGLAFVVAPDPRLPGALPSQYLGLLSAADVGNATNHVLAVEFDTVQDFEFGDINDNHVGVDLNSLVSNASASAA---------PVNLKSGDTIVAWVDYDGGAKLLNVSIAAASASKPASPLISFHVDLSPIFLDQMFVGFSASTGLLASSHYLMGWSFKLGGGAAPPLDVPSLPSLPRPAAGGKNRTSAILAAAFSAFVALVALAGAAAYAAHRYKNRDVVEPWELDYGPHRYSYAELRRATRGFRDRELLGAGGFGKVYRGVLPGKPPRTVVAVKRVSHESRQGLREFVAEIASIGRLRHRNLVQLQGWCRRRGDLLLVYDYMPNGSLDKHLFGDGLAAARLTWGARVKVLRDVAAALLYLHEGWERVVLHRDVKASNVLLDGDMSGRLGDFGLAKLHEHGANPSTTRVVGTLGYLAPELTRTGKATAAADVFAFGALALEVVAGRRPIEPRAPPEELVLAEWAWERYAAGEVGAVVDARLRGEFDAGEAEAAVKVALWCSHPAPAVRPTMREVARYLDAGGAAEVPEPPPPPPPPPVSSGEVG-----YYDFVHSYPTSSY 654          

Query:   38 DQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXI-ATVPEYPKLGGHGLAFVLSPSKQLSG-SPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTK-EELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXR--PKQNHTVLILCVTFAVVVVIMLIVFISFYLVRK-LKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGS 683
            D+F +NGF G+   ++L G+A +A +GLL L+N T++++GHAF+ +P+                  + A V  +  L  +G+AFV++PS +LS  +  QYLG+LN ++NGN+ N+IFAVE DT+ + E  D+N NH+GV++NSMKS+ +  A Y+ E       L + S   +Q W+DYD A   L+V ++ L   KP   ++S  VNLSS++ D  +VGFSA+TG++ + HYVLGWSF+ +G A            R  PK    VL + +  A    ++ +V  +F  VR+ ++ +++ E  E+E GPHRFSY+EL +AT GF++K+LLG GGFGRVYKG L  +N ++AVKR+SH+SKQG++EF++E+ SIG LRHRNLV+LLG+CR +G+LL+VYDYM NGSLDKYL+D+ K VL W +RF+IIKGVASGLLYLHE+WEQ VIHRDIKA NVLLD E+NGRL DFGLA+LY+HG +P TT VVGT+GYLAPEL +TGK T  TDVFAFG  +LEV CGRRP+   A  ++ +L+DWV E  +  AAL+ VD +L G +D  EA + +KLGLMC++  PDARPTMRQV +YL+G+  +PEV P+   Y       + G     F+ F  S+P++          D+ A S
Sbjct:   85 DEFTYNGFGGA--NLTLDGMAAVAPNGLLVLSNGTNQMAGHAFHPTPIRLRGGAAGGAVQSFSAAFVFAIVSNFTVLSDNGMAFVVAPSTRLSTFNAGQYLGILNVTDNGNADNNIFAVELDTMLNPEFQDMNSNHIGVDINSMKSVQNHSAGYYDEATGAFNNLSLISRQPMQVWVDYDGATTVLNVTMAPLDVPKPSKPLISAPVNLSSVVTDTAYVGFSAATGVIYTRHYVLGWSFSQNGAAPSLHTSSLPALPRFGPKPRSKVLEIVLPIATAAFVLALVIAAFLFVRRRVRYAEVREDWEVEFGPHRFSYKELYQATKGFKNKQLLGTGGFGRVYKGVLAKSNLEIAVKRVSHDSKQGMKEFIAEVVSIGHLRHRNLVQLLGYCRRKGELLLVYDYMSNGSLDKYLYDKTKPVLDWGQRFQIIKGVASGLLYLHEDWEQVVIHRDIKASNVLLDGEMNGRLGDFGLARLYDHGVDPQTTHVVGTMGYLAPELVRTGKATPVTDVFAFGVFVLEVTCGRRPLGCIAPDDQNVLLDWVQEHERRHAALDTVDARLCGKYDADEARLALKLGLMCAHPLPDARPTMRQVTQYLDGDAPMPEVAPTMVSYTMLALMQNDG-----FDSFAMSFPSTVTSTASPMSADVSAVS 730          

Query:   38 DQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXX-XIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTK-EELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXX--XXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKK-SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYP 665
            ++F+FNGF  +G  +S  G+A +  +GLL LTN T+++ GHAF+ SPL                   I  +  +  L  HG+AF+++ SK L+ + P Q++GL+N++ NGN+ NH+FAVEFDT+ + E  D++ NHVG++VN + S+ +  A Y+ +     + + + S   +Q W+D+D    +++V ++ L   +P+  +LS  VN+SS++ D  +VGFS++TG+L   HYVLGWSF M+G A               PK     L + +  A  V++  +    F  +R+ +  S++ E  E+  GPHRFSY++L  AT GF DK LLG GGFGRVY+G L  +  +VAVK+++H S+QG+REF++E+ SIGRLRHRNLV+LLG+CR +G+LL+VYDYMPNGSLDK L+D+ K  L W +RF+II+GVASGLLYLHE+WEQ V+HRDIKA NVLLD+++NGRL DFGLA+LY+HGT+P TT VVGT+GYLAPEL  TGK + A+DVFAFGA +LEVACGR+P+   A    ++LVDWV +RW++GA  + VDP+L+GDF E EA +V++LGL+CS+  P ARP  RQ+V+YLEG+V LPE+ P+   ++        G     F+ +V SYP
Sbjct:   30 ERFVFNGF--TGANLSFDGMATVTSNGLLMLTNGTNQLKGHAFFPSPLQFQRGPNSTAMQSFSTAFVIGIIGAFEDLSSHGMAFIIAKSKNLTSALPGQFMGLVNSANNGNATNHLFAVEFDTILNSEFNDMSGNHVGIDVNGLNSVDADNAGYYDDGTGDFKNMSLVSRRPMQVWVDFDGQTMQVNVTMAPLEVARPKKPLLSKIVNISSVIDDTAYVGFSSATGILFCRHYVLGWSFKMNGAAPALNISSLPSLPVTFPKPRSKTLEIVLPIASAVLVFAVAAAVFVFMRRRRMFSELKEEWEVTFGPHRFSYKDLFHATDGFSDKRLLGIGGFGRVYRGVLPSSKAEVAVKKVAHGSRQGMREFVAEVVSIGRLRHRNLVQLLGYCRRKGELLLVYDYMPNGSLDKQLYDQGKITLRWAQRFRIIRGVASGLLYLHEDWEQVVVHRDIKASNVLLDADMNGRLGDFGLARLYDHGTDPHTTHVVGTMGYLAPELGHTGKASKASDVFAFGAFMLEVACGRKPVAQDARDNRVVLVDWVLDRWRAGAITDTVDPRLHGDFVESEASLVLRLGLLCSHPLPGARPGTRQLVQYLEGDVPLPELSPTYQSFNMLALMQDQG-----FDPYVMSYP 657          

Query:   38 DQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXR--PKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKK-SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYL-FDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSY 664
            DQF+F+GF  SG  ++L G A +   GLL LTN T+++ GHAF+ +PL                   A +  YP L  HG+AFV++PS  LS +  +QY+GL N   NGN++NHIFA E DT++++E  DIN+NH+GV++N + S+ S  A Y+ +N +   + + SG  +QAW+DYD    ++++ +  +   KP  S++S   NLS +L +  F+GFS++TG + S HY+LGWSF M+  A            R  PK    VL++ +  A+   I+ +     +LVR+ ++ +++ E  E E GPHRF+Y++L  AT GF DK +LG GGFGRVYKG L  +  +VAVKR+SHES+QG++EF++E+ASIGR+RHRNLV+LLG+CR +G+LL+VYDYM NGSLD+YL ++  K VL W ++F+IIK VASGLLYLHE+W++ VIHRDIKA NVLLD E+N RL DFGLA+LY+HGT+  TT +VGT+GYLAPEL  TGK +  TDVFAFG  LLEV CG+RPI+  A   +++LVDWV E W + + L+ VDP+L GD++  EA +V+KLGL+CS+ + +ARP M+QVV YLEG+  +PE+  +   ++        G     F+ ++ SY
Sbjct:   28 DQFVFSGF--SGANVTLDGTATVTAGGLLELTNGTTQLKGHAFFPAPLSFRGSLNGTVQSFSASFVFAILTSYPNLSCHGIAFVVAPSNNLSTALAAQYMGLTNIDNNGNASNHIFAAEIDTMQNVEFQDINNNHIGVDINGLHSVESHYAGYYDKNGSFHNMNLISGDVMQAWVDYDGDIAQINITIGPIDMSKPGRSLISTTYNLSDVLMEPSFIGFSSATGPINSRHYILGWSFGMNKPAPNIDIAKLPKLPRLAPKPQSKVLVILLPIAIAAFILSVGIAMVFLVRRRQRYAELREDWEDEFGPHRFAYKDLLHATDGFSDKHILGAGGFGRVYKGILPKSKLEVAVKRVSHESRQGMKEFVAEVASIGRIRHRNLVQLLGYCRRKGELLLVYDYMSNGSLDRYLHYEGNKPVLDWVQKFQIIKDVASGLLYLHEKWDKVVIHRDIKASNVLLDKEMNARLGDFGLARLYDHGTDAHTTHMVGTMGYLAPELIHTGKASTLTDVFAFGTFLLEVICGQRPIKEDAHGNQILLVDWVLEHWHNESLLDTVDPRLQGDYNVEEACLVLKLGLLCSHPSTNARPCMQQVVDYLEGDTPVPELASTHRNFNELASMRKKG-----FDPYIMSY 653          

Query:   40 FIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLX----XXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTK-EELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSE-KPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSG----EAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVR-KLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFD-EPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKAL--------PEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPS 637
            F+++GF G+   ++L G+A +   GLL LTN T    GHAF+  P+                       A V E+  L   G AF+++PS+ LS + P QYLG+ NAS NG++ N IFAVEFDTV++ E  DIN+NHVGV+VNS+ S A+  A Y+ +     + L + S   +Q W+DYD+A   + V ++     +P+  +LS  VNLS+++ D  +VGFS+++ ++   HYVL WSF + G     A             PK     L + +      +++  V + F L+R +L+ +++ E  E+E GPHRFS+++L  AT GF+DK LLG GGFGRVYKG L  + T+VAVKR+SHES+QG+REF++E+ SIGR+RHRNLV+LLG+CR +G+LL+VYDYMPNGSLDKYL   + K +L W +R  IIKGVASGLLY+HE+WEQ VIHRDIKA NVLLDSE+NGRL DFGLA+LY+HG +P TT VVGT+GYLAPE+ ++GK T  +DVFAFGA LLEV CGRRPIE +           +  +LVDWV   W+ GA  + VD KL G++D  EA +V++LGL C + +P ARP+MRQV++YL+G   LPE+ P+
Sbjct:   49 FVYDGFGGAA--LALDGMATVTPGGLLLLTNDTDMNKGHAFHPDPVRFVGGGGGGGGGVVASFSTTFVFAIVSEFLDLSTSGFAFLVAPSRDLSAAMPQQYLGMFNASGNGDARNRIFAVEFDTVRNPEFADINNNHVGVDVNSLNSSAAATAGYYDDATAAFQNLSLISRQPMQVWVDYDAAAAEVTVAMAPARRPRPKKPLLSTAVNLSTVVADAAYVGFSSASSIVLCKHYVLSWSFRLGGGGAAPALDYAKLPKLPRIGPKPRSKALTVALPIVTTAIVLTAVAVGFLLLRQRLRYAELREDWEVEFGPHRFSFKDLYDATGGFKDKRLLGAGGFGRVYKGVLPRSRTEVAVKRVSHESRQGMREFIAEVVSIGRIRHRNLVQLLGYCRRKGELLLVYDYMPNGSLDKYLHGCDEKPILDWAQRIYIIKGVASGLLYMHEDWEQVVIHRDIKASNVLLDSEMNGRLGDFGLARLYDHGADPQTTHVVGTMGYLAPEMVRSGKATTRSDVFAFGAFLLEVTCGRRPIEEEEEVAGAGADDDDRFVLVDWVLGHWREGAITDAVDAKLRGEYDAAEAELVLRLGLTCLHPSPAARPSMRQVMQYLDGSAPLPELPPT 665          

Query:   38 DQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGSPS-QYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLE-NRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLV---RKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFD-EPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVV 635
            DQ ++ GF  +      T V  +  +GLL LTN T    GHAFY SPL                   A    YP++  HGLAFV+SPS   S + + QYLGLLN+   G+ +NHI A+EFDT+ ++E  DI+DNHVG+++N + SI S  A Y+ + N + + + + SG  +QAW+DY+    ++ V ++ +   KP+  ++ I  +LS++L++  ++GFSASTGL+ S HY+LGWSF M+  A            R   N    +L +T  +     +I+F   ++    R+L+  ++ E  E+E GPHRFSY++L  AT GF +K LLG GGFG+VYKG L  +  +VAVKR+SHES+QG++EF++E+ SIGR+RHRN+V+LLG+CR +G+LL+VYDYMPNGSLD YL++ E K  L WD+RF+IIKG+ASGL YLH++WE+ VIHRDIKA NVLLD+E+NGRL DFGLA+LY+HGT+  TT VVGT+GYLAPEL  TGK +  TDVFAFGA LLEV CG+RP+   +     +LVDWV E WQ G     VD +L GD++  EA  V+KLGL+CS+   + RP M+QV++YL+G+V LPE+ 
Sbjct:   48 DQLLYLGFTSANLITDDTTV--VTSNGLLELTNGTINRKGHAFYPSPLHFRKSHNNKVHSFAVSFVFAIRSSYPRMSLHGLAFVVSPSINFSNALAIQYLGLLNSKNRGSKSNHILAIEFDTILNIEFEDIDDNHVGIDINDLHSIKSHSAGYYDDRNSSFQNMSLISGDAMQAWVDYNGEDKKISVTMAPIKMAKPKRPLILISYDLSTVLKEPSYIGFSASTGLVDSRHYILGWSFGMNKPAPMINVNKLPKLPRQGPNPQPKLLAITLPIASATFVILFCGVFITIVRRRLRYVELKEDWEIEFGPHRFSYKDLFHATHGFDNKNLLGAGGFGKVYKGVLPSSKLEVAVKRVSHESRQGMKEFVAEVVSIGRIRHRNIVQLLGYCRRKGELLLVYDYMPNGSLDAYLYNNELKPTLSWDQRFRIIKGIASGLFYLHDKWEKVVIHRDIKASNVLLDTEMNGRLGDFGLARLYDHGTDLQTTHVVGTMGYLAPELVCTGKASPLTDVFAFGAFLLEVTCGQRPVNHSSQDSPGVLVDWVLEHWQKGLLTNTVDARLQGDYNIDEACFVLKLGLLCSHPFTNMRPNMQQVMQYLDGDVPLPELT 650          

Query:   38 DQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLX-----XXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLS-GSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTK--EELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEA---QXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIE-----PKALPE--ELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPS 637
            DQF ++GF  +G  + L G+A +   G L LTN TS++ GHAF+ +PL                        A   +Y  + G+GLAF ++PSK +S  SPSQ+LGL N+  NGN++N +FAVE DT+ + E  DIN NHVGV+VN + S+A+ PA Y+ +      + L + SGA +Q W+DYD     ++V L+ +   KPR  ++S+ V+LS ++    +VG S+STG   + HYVLGWSF M G A                 +++  + ++    A ++ + ++  +SF + R+L+ +++ E  E+E GPHRF+Y++L  AT GF  K LLG GGFGRVY+G L  + T+VAVK +SH++KQG+R+F++E+ SIGRLRHRN+V LLG+CR RG+LL+VYDYMPNGSLD++L D     LGW +R   ++GVA+GLLYLHE+WEQ V+HRD+KA NVLLD E+N RL DFGLA+LY+ G +P TTRVVGT+GYLAPEL  T + T ATDVFAFG+ +LEVACGRRPIE       A  E  +L+L DWV +RW  G      D +L GD+D  EA +V+KLGL+CS+    ARPTMRQVV +L+G+  LPE  P+
Sbjct:   34 DQFRYDGF--AGAALDLDGMAVVEPDGKLMLTNVTSQMKGHAFHPAPLRFHHPPPANGTAAAARSFSTAFVFAIAADYVTVSGNGLAFFVAPSKNMSTASPSQFLGLFNSENNGNASNRVFAVELDTILNPEFRDINSNHVGVDVNGLVSVAAEPAGYYDDATGGAFKNLTLFSGAAMQVWVDYDGRAAVVNVTLAPVEVAKPRRPLISVAVDLSPVVNGTAYVGLSSSTGPFHTRHYVLGWSFAMDGPAPPLDYAKLPKMPVVSAKRRSKALDVVIPVAAPLLALAVVAGVSFLVWRRLRYAELREDWEVEFGPHRFAYKDLFVATAGFDGKRLLGVGGFGRVYRGVLPASGTEVAVKIVSHDAKQGMRQFVAEVVSIGRLRHRNVVPLLGYCRRRGELLLVYDYMPNGSLDRWLHDHGAPPLGWAQRLHAVRGVAAGLLYLHEDWEQVVVHRDVKASNVLLDGEMNARLGDFGLARLYDRGADPQTTRVVGTMGYLAPELAHTRRVTPATDVFAFGSFVLEVACGRRPIERGGAMTAAADEDGQLVLADWVLDRWHKGDIAAAADARLCGDYDAKEAALVLKLGLLCSHPVAAARPTMRQVVHFLDGDAPLPEPEPT 650          

Query:   39 QFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLS-GSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTK-EELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEA------QXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRK-LKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKR-VLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPE-ELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVV 635
            QF+FNGF  S   +++ G A +   GLL LTN T  + GHAF+ +P                      +  Y ++G  G+AF+++PS   S  + +Q+LGL N   NGN +NH+FAVE DTV++ E  DI+ NH+G++++ ++S+ S+ A Y+ +N    + + + SG  IQ WIDYD+   R+DV L+     KP   +L +  NLS +L D  +VG SA+TG L +SHY+LGWSF+M+G A      Q           +  +   VL++ V  A     + +    F  VR+  K +++ E  E++ GPHRFS++ L  AT GF+++ LLG GGFGRVYKG L  +  Q+AVKR+SHES+QG+REF++EI SIGRLRHRN+V+LLG+CR +G+LL+VYDYMPNGSLDKYL     R  L W++RF+IIKGVASGL YLH EWEQ VIHRD+KA NVLLD E+N RL DFGLA+LY+HGT+  TT +VGT+GYLAPEL  TGK + ATDVF+FG  +LEVACGRRPIE     E +  LVDWV +RW  G+ LEV+DPKL   +D+ EA + +KLGL+CS+ +P ARPTM  V++YL  ++  PE++
Sbjct:   79 QFVFNGFLNS--SLTVDGAAMVLPGGLLQLTNGTGMMKGHAFHPTPFRFRESPGTTLHSFSVSIVFGIISAYREVGTDGMAFLIAPSSNFSDANAAQHLGLFNYKNNGNMSNHVFAVEIDTVRNNEFMDIDSNHIGIDISDLRSVNSSSAGYYDDNTGGFQNMSLISGEAIQIWIDYDARAMRIDVALAPFKMAKPTKPLLLMSYNLSMVLTDVAYVGLSAATGPLETSHYILGWSFSMNGSAPSFLTAQLPDLPRRGTDRKGSRRSKVLLIIVPIATATSAVAVSLAVFLFVRRWFKYAELREDWEIDFGPHRFSFKNLYFATEGFKNRHLLGTGGFGRVYKGFLFESKLQIAVKRVSHESRQGIREFIAEIVSIGRLRHRNIVQLLGYCRRKGELLLVYDYMPNGSLDKYLHCNSTRPSLDWNQRFRIIKGVASGLWYLHGEWEQVVIHRDVKASNVLLDEEMNARLGDFGLARLYDHGTDMQTTHLVGTIGYLAPELANTGKASPATDVFSFGIFVLEVACGRRPIEHGMNSEYKFTLVDWVIDRWHEGSLLEVMDPKLQNGYDDDEACLALKLGLLCSHPSPIARPTMWHVMQYLNHDLPFPELM 685          

Query:   38 DQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAK-IQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSF--NMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLI-VFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLF-DEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYD 642
            DQFI+ GF GS   ++L G A I  +GLL LTN T R+ GHA + +PL                     +  +  + GHG AF ++PS   S + P Q+LGLLN   NG+S NH+FA+E DT+++ E GDI++NHVG+++NS+ S+ S+   ++ +N      +   G K +Q W++YD    ++DV L+ L   +P+  +LS+  NLS++L D  ++GFS+STGL    HYVLGWSF  N+                 P+    +L + +  A  + ++ I V I   + R L+  ++ E  E+E GPHRF+Y++L  AT GF++K L+G GGFGRVYKG L  +  +VA+KR+S+ESKQG++EF++E+ SIG L+HRN+V+LLG+CR +G+LL+VYDYM NGSLDKYL   E K  L W +RF+IIK +ASGLLYLHEEW++ VIHRD+KA NVLLD +LNGRL DFGLA+LY+HGT+P TT VVGT+GYLAPEL   GK T  TDVF+FG  +LEV CG++PI+  +   +LILVDWV + W  G+ L+ +D K+ G++D  EA +V+KLGLMCS+  P+ RP +RQV++YL+G+V LPE+ P    +D
Sbjct:   28 DQFIYTGFTGS--NLTLDGAAKITATGLLGLTNDTFRIKGHASHPAPLCFRKSPNGTVQSFSVSFVFGILSSFGDIRGHGFAFFIAPSNDFSTAFPIQFLGLLNDINNGSSTNHLFAIELDTIRNDEFGDIDNNHVGIDINSLNSVRSSYVGFYNDNNGALTNVSLIGDKPMQVWVEYDGNATQIDVTLAPLGIGRPKRPLLSVVHNLSTVLTDQAYLGFSSSTGLSTGHHYVLGWSFGLNIPAPIIDPTKLPKLPNLSPRPQSKLLEIVLPIASAIFVLAIGVAIVLLVRRHLRYKEVREDWEVEYGPHRFAYKDLFDATKGFKNKNLVGTGGFGRVYKGVLPNSRLEVAIKRVSYESKQGIKEFVAEVVSIGHLQHRNVVKLLGYCRRKGELLLVYDYMANGSLDKYLHRQEGKPTLNWGQRFQIIKDIASGLLYLHEEWDKVVIHRDVKASNVLLDKQLNGRLGDFGLARLYDHGTDPQTTHVVGTIGYLAPELVHRGKATTLTDVFSFGIFILEVTCGQKPIKEDSQGRQLILVDWVLQNWHKGSLLDTMDIKIQGNYDIGEACLVLKLGLMCSHPFPNVRPNVRQVMQYLDGDVPLPELKPEHFSFD 637          

Query:   24 VFLVFSSGHVFSQL--DQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPL-----XXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKE--ELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXX----XXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEV 634
            +FL   S H+ +    DQF F+GF  +G  ++L G A +   GLL LTN T+ + GHAFY SPL                          V EY  L   GLAFV++ S+  S +  SQY+GL NA  NGN++NH  AVE DT+ + E GD++DNHVG++V+ + S A+  A Y  ++RT     + + S A  + W+D+D+  + ++V ++ L   KP + +LS  VNLS++++D  +VGFS+STG++AS HYVL WSF M G A                R   N   ++L +  A +V  + I  +  +  R+ + +++ E  E+  GPHRFSY++L +AT GF D+ LLGFGGFGRVYKG L  +  ++AVK++SHES+QG++EF++E+ SIG+LRHRNLV+LLG+CR +G+LL+VYDYMPNGSLDKYL+ E  ++L W +RF+IIKG+AS +LYLHE+WEQ V+HRDIKA NVLLD+E+N RL DFGLA+LY+ GT+P TT VVGT+GYLAPEL  TG+P+ A+D+FAFG  +LEV CGRRP+       +L+LVD V E W+ G   + VDP+L GDF   EA +V+KL L+CS+  P ARP +RQVV+ L+G + LPE+
Sbjct:   15 LFLSLGSFHLAAAAVDDQFTFDGF--AGVNLTLDGTAVVTPGGLLMLTNGTTLLKGHAFYPSPLRFFHEATSGGGSSTVRSFSTAFVFGIVSEYADLSSPGLAFVVAKSRDFSSALQSQYMGLANARNNGNASNHFLAVELDTIVNAEFGDMSDNHVGIDVDGLASAAADDAGYH-DDRTGAFVNMSLLSRAAARVWVDFDARTSLVNVTMAPLELPKPTTPLLSAAVNLSAVIEDEAYVGFSSSTGVVASRHYVLAWSFKMDGPAPSLNVSKLPALPVTIARAPSNVLKILLPIASAALVSALAIAVLVIHR-RRRRYAELKEEWEVAFGPHRFSYKDLFRATNGFSDERLLGFGGFGRVYKGVLLVSRVEIAVKKVSHESRQGMKEFIAEVVSIGQLRHRNLVQLLGYCRQKGELLLVYDYMPNGSLDKYLYAENSKILSWAQRFRIIKGIASSILYLHEDWEQVVLHRDIKASNVLLDAEMNCRLGDFGLARLYDRGTDPHTTHVVGTIGYLAPELGHTGRPSKASDIFAFGVFMLEVTCGRRPVLQDTNGGQLLLVDMVLEHWRQGTVTDAVDPRLQGDFAVEEASLVLKLCLLCSHPLPSARPGIRQVVQLLDGAMPLPEL 636          

Query:   33 VFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFE--DFVHSYPNSPYL--------DVEDRDVDIEAGSTKHL 687
            VFSQLD   F GF+   + MSL G A I  +G+L LTN T    GHAFYSSP+                     VPE P++ GHG AF +S SK+L G+ P+QYLGLLNA+++GN +NH+FAVEFDTVKD +L DINDNHVG+++NS+ S  S PAA FL N T ++L + SG  IQAW+DYDS KN L+V+LS  S++P S ILS  ++LS + +D+M+VGFS+STGLL S+HY+LGWSF+M GEA+             K NHT LIL V+     +I+LIV  +FYL RK+KK+D+ EA EL+IGPHRFSYQELKKAT  FRD+ELLGFGGFG+VYKGTL  +NT++AVKRI HES QGL+EF++EI SIGRLRHRNLVRLLGWCR +GDLL+VYD+M NGSLDKYLFD PK +L W++R  II+GVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRL DFGLAKLY+  +NP TT+VVGTLGYLAPELT+TGKPT ++DVFAFGA+LLEV CGR+PIEPKALPEELILVD VW+RW+SGA L+VVDP+LNG+F+E EA++V+KLGLMCSN+AP+ARP MRQV R+LEGEVALP +V +P  YD K  +     N +R E  D  HSYP S  L        D +  D DIEAGS   L
Sbjct:   15 VFSQLDDLYFPGFNHVTSNMSLNGAAVIEKNGILRLTNNTQHTVGHAFYSSPVKFKNSSNGKSFSFSTAFAFTIVPENPRIRGHGFAFTISTSKELPGALPNQYLGLLNATDSGNFSNHLFAVEFDTVKDYDLHDINDNHVGIDINSVISNKSVPAASFLVNSTTKDLNLCSGRPIQAWVDYDSIKNLLEVRLSSFSKRPVSPILSCKIDLSPLFKDYMYVGFSSSTGLLTSTHYILGWSFSMKGEAKSLSLPSLPSLPGHKMNHTGLILGVSTLATFLIILIVATTFYLSRKMKKADVTEAWELDIGPHRFSYQELKKATKNFRDEELLGFGGFGKVYKGTLPNSNTEIAVKRICHESTQGLKEFLTEIDSIGRLRHRNLVRLLGWCRQQGDLLLVYDFMANGSLDKYLFDNPKTILKWEQRLNIIQGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLGDFGLAKLYDRNSNPITTKVVGTLGYLAPELTRTGKPTTSSDVFAFGALLLEVVCGRKPIEPKALPEELILVDLVWDRWKSGAILDVVDPRLNGEFNEHEAVLVLKLGLMCSNNAPNARPPMRQVARFLEGEVALPALVAAPNAYDGKNVNA----NKVRRELVDHKHSYPVSSNLEKVSTWSFDGDYGDTDIEAGSDSAL 676          

Query:   29 SSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNS 667
            +  HV +QLD   F GF+   N MSL G A+I  +GLL LTN +  + GHAFYS  +                   A VP+YP LGGHGLAF LS S +L G+ P +YLGLLN +  G+ + HIF+VEFDT KD +  DINDNHVGVN+NSM S  S PAAYFL N  KEEL + SG  IQAW+DYDS KN+L+V+LS  S KP   ILSID++LSSIL D M+VGFS+STG+L S+HYVLGWSF+++GEA+             K    +++     +  V+I+ I  +SFYLVRK+K +D+IE  EL++GP RFSYQEL++AT GFR+KELLGFGGFG+VYKGTL    T +AVKR  HESKQGLREF +EIASIGRLRH+NLVRLLGW R RG+LL+VYD+MPNGSLDKY+F+EPK +L W++RFKI+K VASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRL DFGLAKLYE G+NP TT+VVGTLGYLAPELTKTGKPT ++DVFAFGA+LLEV CGRRPIEPKALPEELILVDWVW++W+SGA L+VVDP+LNG+FDE EA++++KLGLMCSN  P ARP MR++VRYLEGEVALPE+V +P  YD +    +        +D ++ YP S
Sbjct:   16 NQNHVLTQLDDLYFQGFNHVRNNMSLNGAAEIEKNGLLSLTNNSKSILGHAFYSHQIKFKNSTSGKAFSFSTAFVFAVVPKYPNLGGHGLAFTLSTSNELPGAFPRKYLGLLNTTVAGSFSYHIFSVEFDTHKDYDFFDINDNHVGVNINSMISNKSVPAAYFLLNSEKEELDLTSGNPIQAWVDYDSVKNQLEVRLSPSSTKPIYPILSIDIDLSSILNDSMYVGFSSSTGMLTSTHYVLGWSFSVNGEAKSFSMSSLPSLPETKDLLVLVVCVSVGSTFVIILGIA-VSFYLVRKIKDADMIEGWELQVGPRRFSYQELREATRGFREKELLGFGGFGKVYKGTLPNCGTPIAVKRFCHESKQGLREFSTEIASIGRLRHKNLVRLLGWSRLRGELLLVYDFMPNGSLDKYIFEEPKTILKWEQRFKIVKDVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLGDFGLAKLYERGSNPITTKVVGTLGYLAPELTKTGKPTTSSDVFAFGALLLEVICGRRPIEPKALPEELILVDWVWDKWKSGAILDVVDPRLNGEFDETEAVLLLKLGLMCSNYVPRARPLMRKIVRYLEGEVALPELVAAPDVYDGENADANTDSGD-ECKDHMYFYPQS 653          

Query:   22 FWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFL--ENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXR-PKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGG 640
            F   +  S   V SQL++F+++GF  +   ++L+GV++I  +G+L LTN TSR+ GHAFY SP                      VPEYPKLGGHGLAF ++ +K L   PSQYLGLLN+S   N  NH+FAVEFDTV+D E GDINDNH+G+++ S+KS AS  AAY+    + +K++L +K G  IQ WIDYDS +N ++V +S  S+KP+  ILS  V+LSS+ +++M+VG SASTGLLASSHY+LGWSF ++G+A               K+ +T L++ V+ AVVV +++ +  + YL+RK+K +DI+E  ELE+GPHR+ YQELKKAT  F DK LLG GGFG+VYKG L  +  +VAVKRIS ES QGLREF+SEIASIGRLRHRNLV+LLGW R R D L+VYDYM NGSLDK+LF+EPK +L W++RFKIIK VASGLLYLHE +EQ VIHRD+KA NVLLD ELNGRLSDFGLA+LYEHG NP TTRVVGTLGYLAPEL +TGK T ++DV+AFGA+LLEV CGRRPIEPKALPEEL+LVD VWE+++ G AL+V+DPKLNG+++E E ++VIKLGLMCS++AP ARP+MRQVVRYL+ EV +P+ +  P G
Sbjct:    8 FSALIFLSIIPVSSQLNEFLYSGFKDAATNITLSGVSEIQKNGILRLTNETSRLLGHAFYPSPFKFKNSSNGTALSFSTCFVFIIVPEYPKLGGHGLAFTIATTKDLKALPSQYLGLLNSSVV-NLTNHLFAVEFDTVQDFEFGDINDNHIGIDLGSLKSNASASAAYYTGDSDSSKQDLNLKGGKPIQVWIDYDSVQNVVNVTISPTSKKPKIPILSSHVDLSSLFEEYMYVGLSASTGLLASSHYMLGWSFKLNGQAPALDLSSLPSLPGGHKKQYTGLVIGVSAAVVVFVIVSISTAIYLIRKIKNADIVEDWELEMGPHRYCYQELKKATNNFSDKVLLGKGGFGQVYKGILPDSKIEVAVKRISKESTQGLREFVSEIASIGRLRHRNLVQLLGWYRRRDDFLLVYDYMANGSLDKFLFEEPKMILNWEQRFKIIKDVASGLLYLHEGYEQVVIHRDVKASNVLLDEELNGRLSDFGLARLYEHGANPNTTRVVGTLGYLAPELPRTGKATESSDVYAFGALLLEVVCGRRPIEPKALPEELVLVDLVWEKFREGRALDVIDPKLNGEYNESEVMMVIKLGLMCSHNAPIARPSMRQVVRYLDEEVGIPQNLRDPNG 628          

Query:   38 DQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXX--XXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFL-ENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSE-KPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFIS--FYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEV 634
            +QFI++GF  +G  + L+ +A I  +GLL LTNT+ R+ G AF+  P                      A VPE P  GG G+AF +SPS   +G+  +QY G+LN++ NG S+NH+ AVE D V   +L DINDNHVG++VNS+ SI S P  YF  E +  + L + SG  +  WIDYD  +  L+V ++ ++  KP   +LS  ++LSS++ D M+VGFS+STG +ASSHY+LGWSFN  G+AQ             +++     L +    +  I+L+V IS    ++R+ K  ++ E  E + GP RFSY++L KAT GF D ELLG GGFG+VY+G L  +N QVA+K++SH+S+QG +EF++EI S+GRLRHRNLV+L G+CR +G+LL+VYDYMPNGSLDK LF      L W  R++II+GVAS LLYLHEEWEQ V+HRD+KA NVLLD++LNGRL DFGLAK ++HG+ P TT+VVGT+GYLAPE+T+TGK T  +DVF+FG  +LEVACGR+P+E +  PEE++LVDWV E W+ GA L  VDP+  G+  E E  VV+KLGL+C++  P ARP+MRQ V+YL+G   LP++
Sbjct:   29 NQFIYHGF--TGANLLLSEIAKIHPNGLLELTNTSKRIIGRAFFPFPFQFNTSLFNNSRSLSFSTQFAFAMVPELPTHGGQGMAFTISPSVNFTGALATQYFGILNSTSNGLSSNHLLAVELDAVPSPDLKDINDNHVGIDVNSLISIESAPVTYFSDEEKENKSLTLISGHVMHVWIDYDEVEMLLNVTVAPITRTKPTLPLLSTPLDLSSVMLDSMYVGFSSSTGAVASSHYILGWSFNRGGQAQSLDVSKLPTLPTRRKSRKKPHLRIVVPTITAIILLVAISGDVCIIRRKKYEELREDWEQDYGPQRFSYKDLYKATKGFSDSELLGCGGFGKVYRGVLSSSNMQVAIKKVSHDSRQGAKEFVAEIVSMGRLRHRNLVQLFGYCRRKGELLLVYDYMPNGSLDKLLFRNDTPCLNWGRRYQIIRGVASALLYLHEEWEQVVMHRDVKASNVLLDADLNGRLGDFGLAKFHDHGSTPQTTKVVGTVGYLAPEITRTGKSTTCSDVFSFGTFMLEVACGRKPVESERPPEEVVLVDWVLECWKRGAILGTVDPRFEGNHVEEEMEVVLKLGLLCTHRTPAARPSMRQAVQYLDGNATLPDL 630          

Query:   39 QFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLE-NRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISF--YLVRKLKK-SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP---SPGGYDSKKGHGSGGINTIRFEDFVHSYPNS 667
             F ++GF  +   +SL G+A++  +GLL LTN T + + HAFY +P+                   A +PEYP LGGHG+AFV++P++ L G+ PSQYLGL N + NGN  NH+ AVE DT+   E  DI+DNHVG+++N ++S  S  A Y+ + N     L + SG  +Q W++YD  + +LDV ++ +  +KP   +L++  +LS IL   M++GFS+STG + +SHYVLGWSF M+G A+           R     T   L +   V+ + +++V +S   Y +R+ +K ++++E  EL+ GPHRF Y++L  AT GFRD+ELLG GGFGRVYKG L  +  Q+AVKR+SHES+QG+REF++EI SIGRLRHRNLV LLG+CR RG+LL+VYDYMPNGSLDKYL+D+P   L W +RF++I GVASGL YLHEEWEQ VIHRD+KA NVLLD ELNGRL DFGLA+LY+HGT+P TT VVGTLGYLAPE  +TGK T +TDVFAFGA LLEVA GRRPI+P    E++ILVDWV+ RW                           LG         ARP+MRQVV++LEG+V LP++ P   S  G       G        F++F +SYP+S
Sbjct:   26 NFTYSGFRST--NLSLDGLAELTSNGLLRLTNETKQRTSHAFYPNPVTFKNSINSTAFTFSTTFVFAIIPEYPTLGGHGIAFVIAPTRGLPGALPSQYLGLFNKTNNGNQTNHVVAVELDTIYSSEFNDIDDNHVGIDINGLESERSASAGYYSQLNGKLTNLTLISGHPMQVWMEYDGKEKQLDVTIAPIDVDKPSRPLLTLSCDLSPILNSSMYIGFSSSTGSVFTSHYVLGWSFKMNGLAEALHISRLPKLPRVGPKKTSKFLTIELPVLCLSLVLVAVSSTSYAIRRTRKFAEVLEDWELDYGPHRFKYKDLYTATKGFRDEELLGSGGFGRVYKGVLPTSKIQIAVKRVSHESRQGMREFVAEIVSIGRLRHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYDQPTVALNWSQRFRVINGVASGLFYLHEEWEQVVIHRDVKASNVLLDRELNGRLGDFGLARLYDHGTDPQTTHVVGTLGYLAPEHARTGKATTSTDVFAFGAFLLEVASGRRPIQPT---EDIILVDWVFSRW---------------------------LG---------ARPSMRQVVQFLEGDVPLPDISPLCLSASGLTFSHREG--------FDEFANSYPSS 614          

Query:   38 DQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIA--TVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFL-ENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSE-KPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFIS--FYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEV 634
            +QFI++GF  +G  + L+ +A I  +GLL LTNT+ +  G AF+  P                    A   VPE P LGG G+AF +SPS   +G+  +QY G+LN++ +G  +NH+ AVE DTV+  +L DIN++HVG++VNS+ SI S P  YF  E +  + L + SG  +  WIDYD  +  L+V ++ ++  KP   +LS  ++LSS++ + M+VGFS+STG +AS++Y+LGWSFN  G+AQ             +++     L +    +  ++L+V IS    ++R+ K  ++ E  E E GP R SY++L KAT GF DKELLG GGFG+VY+G L  +N QVAVK++SH+S+QG +EF++EI S+GRLRHRNLV+L G+CR +G+LL+VYDYMPNGSLDK LF      L W  R++II+GVAS LLYLHEEWEQ V+HRD+KA NVLLD++LNGRL DFGLAK ++HG+ P TT+VVGT+GYLAPE+T+TGK T  +DVF+FG  +LEVACGR+P+E +  PEE++LVDWV E W  GA L  VDP++ G+  E E  VV+KLGL+C++  P ARP+MRQ V+YL+G   LP++
Sbjct:   29 NQFIYHGF--TGANLLLSEIAKIHPNGLLELTNTSKQQIGRAFFPFPFQFNTSLFNNSRSLSFSTQFAFSMVPELPTLGGQGMAFAISPSVDFTGAVAAQYFGILNSTSDGLPSNHLLAVELDTVQSQDLKDINESHVGIDVNSLISIESAPVTYFSDEEKENKSLTLISGHVMHVWIDYDEVEMLLNVTVAPVTRTKPTLPLLSTPLDLSSVMLNSMYVGFSSSTGAMASNNYILGWSFNRGGQAQSLDVSKLPTLPTRRKSRKKPQLRIVVPTITAVILLVAISGDVCIIRRKKYEELREDWEQEYGPQRISYKDLYKATKGFTDKELLGCGGFGKVYRGVLPSSNMQVAVKKVSHDSRQGTKEFVAEIVSMGRLRHRNLVQLFGYCRRKGELLLVYDYMPNGSLDKLLFRNETPSLNWGRRYQIIRGVASALLYLHEEWEQVVLHRDVKASNVLLDADLNGRLGDFGLAKFHDHGSTPQTTKVVGTVGYLAPEITRTGKSTTCSDVFSFGTFMLEVACGRKPVESERPPEEVVLVDWVLECWNRGAILGTVDPRIEGNHVEEEMEVVLKLGLLCTHRTPAARPSMRQTVQYLDGNATLPDL 630          

Query:   38 DQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIA--TVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFL-ENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSE-KPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFIS--FYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEV 634
            + FI++GF  +G  + L+ +A I  +GLL LTNT+++  G AF+  P                    A   VPE P LGGHG+AF +SPS   +G+  +QYLG+LN++ NG S+NH+ AVE D ++ L+  DINDNHVG++VN + SI S P  YF  E    + L + SG  +  WIDYD  +  L+V ++ ++  KP   +LS  ++LSS++ D M+VGFS+STG +ASSHY+LGWSFN  G+AQ             +++     L +    +  ++L+V IS   Y++R  K  ++ E  E E GP RFSY++L KAT GF D++L+G GGFG+VY+G L  +  QVA+K++SH+S QG ++F++EI S+GRLRHRNLV+LLG+CR +G+LL+VYDYMPNGSLDK LF      L W +R+++++GVAS L+YLHEEWEQ V+HRD+KA N+LLD + NGRL DFGLAK Y+ G NP TT VVGT+GY+APE+T+TG+ T ++DVFAFG  +LE+ACGR+P+EP+   E++ILVDWV + W+ G  L   DP+L G++   E  +V++LGL+CS   P ARP+MRQ+ +YL+G  +LPE+
Sbjct:   29 NHFIYHGF--TGANLLLSEIAKIHPNGLLELTNTSTQQIGRAFFPFPFQFNTSLFNNSRSLSFSTQFAFSMVPELPTLGGHGMAFTISPSVNFTGAWATQYLGILNSTSNGLSSNHLLAVELDAIRSLDFKDINDNHVGIDVNDLTSIESAPVTYFSGEENENKSLALISGLVMHVWIDYDEVEKLLNVTVAPITRTKPTLPLLSTPLDLSSVMLDSMYVGFSSSTGAVASSHYILGWSFNRGGQAQSLDVSKLPSLPHQRKSRKKSHLRILVPAITAVILLVAISGAAYIIRSKKYEELREDWEQEYGPQRFSYKDLYKATTGFTDRKLVGSGGFGKVYRGVLPSSKMQVAIKKVSHDSIQGTKQFVAEIVSMGRLRHRNLVQLLGYCRRKGELLLVYDYMPNGSLDKLLFRNDTPSLNWVQRYQVLRGVASALIYLHEEWEQVVLHRDVKASNILLDDDFNGRLGDFGLAKFYDRGANPQTTCVVGTVGYIAPEVTRTGRATTSSDVFAFGTFMLEMACGRKPVEPEQSAEKMILVDWVLDSWKIGDILRTGDPRLEGNYVVEEMELVLRLGLLCSFSTPQARPSMRQISQYLDGNASLPEM 630          

Query:   20 IFFWVFLVFSSGHVF--SQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXX--XXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSG-SPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLEN-RTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXX--XRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEV 634
            + F + L  S  H+    +++QFI++GF  +G  +SL G+A I  +GLL LTNT+ +  GHAF+  P                      A VPE P  GGHG+A  +SPS +  G + +QYLGL N++  G S+NH+ A+E D V+  E  DI DNHVG++VN++ SI S PA+YF ++ R  E L + SG  +Q WIDYD  +N L+V L+ +S  KP+  +LS  +NLS ++ + M+VGFS+STG ++S HY+LGWSFN SG+AQ             R   N   L + +    V V+++  F + Y++RK +  ++ E  E + GP RF Y++L KAT GF+ K LLG+GGFGRVY+G L+ +  ++AVK+I+H+S QG++EF++EIA++GRLRHRNLV+LLG+CR +G+LL+VYDYMPNGSLDK+LF + K  L W +R++II+GVAS LLYLHEEWEQ V+HRD+KA NVLLD++LNGRL DFGLAK ++HG+ P TT VVGT+GYLAPE+T+TGK T  +DVF+FG  +LEVACGR+P+E +  PEE++LVDWV E W+ GA L  VDP+  G+  E E  +V+KLGL+C++  P ARP+MRQ ++YL+G   LP++
Sbjct:    8 LHFLLALFISLKHLALAQEVNQFIYHGF--TGANLSLNGIASIHPNGLLELTNTSKQQIGHAFFPFPFHFKSSFPNNSRSLSFSTNFVFAMVPETPTRGGHGIALAISPSTEFKGATATQYLGLFNSTTVGLSSNHLLAIELDAVRSPEFRDIGDNHVGIDVNNLTSIQSAPASYFSKHERENESLQLISGDPMQVWIDYDEMENLLNVTLAPVSIMKPQKPLLSTPINLSLVVLESMYVGFSSSTGSVSSHHYILGWSFNKSGQAQSLDTSKLPSLPPERNSTNKPYLRIMIPLITVSVLLIASFATMYIMRK-RYEEVHEDWEQQYGPQRFRYKDLYKATKGFKVKGLLGYGGFGRVYRGELRSSKVEIAVKKITHDSNQGMKEFVAEIATMGRLRHRNLVQLLGYCRRKGELLLVYDYMPNGSLDKFLFCKVKPNLNWAQRYQIIRGVASALLYLHEEWEQVVLHRDVKASNVLLDADLNGRLGDFGLAKFHDHGSTPQTTNVVGTVGYLAPEITRTGKSTTCSDVFSFGTFMLEVACGRKPVESERPPEEVVLVDWVLECWKRGAILGTVDPRFEGNHVEEEMELVLKLGLLCTHRTPAARPSMRQAMQYLDGNATLPDL 628          

Query:   38 DQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIA--TVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFL-ENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSE-KPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFIS--FYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEV 634
            + FI++GF  +G  + L+ +A I  +GLL LTNT+ +  G AF+  P                    A   V E P LGGHG+AF +S S   +G+  +QYLG+LN++ NG S+NH+ AVE D ++  +  DINDNHVG++VNS+ SI S P  YF  E +  + L + SG  +  WIDYD  +  L+V ++ ++  KP   +LS  ++LSS++ D M+VGFS+STG +ASSHY+LGWSFN  G+AQ             +++     L +    +  I+L+V IS   Y++++ K  ++ E  E E GP RFSY++L KAT GF D++LLG GGFG+VY+G L  +N QVA+K++SH+SKQG ++F++EIAS+GRLRHRNLV+LLG+CR +G+LL+VYDYMP+GSLDK LF        W  R+++++GVAS LLYLHEEWEQ V+HRD+KA N+LLD + NGRL DFGLAK Y+ G NP TT VVGT+GY+APE+T+TG+ T ++DVFAFG  +LE+ACGR+P+EP+   E++ILVDWV + W+ G  L   DP+L G++   E  +V++LGL+CS   P ARP+MR++ +YL+G  +LPE+
Sbjct:   28 NHFIYHGF--TGANLLLSEIAKIHPNGLLELTNTSKQQIGRAFFPFPFLFNTSLFNNSRSLSFSTQFAFSMVSELPTLGGHGMAFTISQSTNFTGALATQYLGILNSTSNGLSSNHLLAVELDAIRSPDFKDINDNHVGIDVNSLISIESAPVTYFSDEEKENKSLTLISGHVMHVWIDYDEVEKLLNVTVAPITRTKPTLPLLSTPLDLSSVMLDSMYVGFSSSTGAVASSHYILGWSFNRGGQAQSLDVSKLPSLPPQRKSRKKPYLRILVPTITAIILLVAISGAAYIIKRKKYEELREDWEREYGPQRFSYKDLYKATTGFTDRKLLGSGGFGKVYRGVLPSSNMQVAIKKVSHDSKQGTKQFVAEIASMGRLRHRNLVQLLGYCRRKGELLLVYDYMPHGSLDKLLFHNDTPSFNWVHRYQVLRGVASALLYLHEEWEQVVLHRDVKASNILLDDDFNGRLGDFGLAKFYDRGANPQTTCVVGTVGYIAPEVTRTGRATTSSDVFAFGTFMLEMACGRKPVEPEQSAEKMILVDWVLDSWKIGDILRTGDPRLEGNYVVEEMELVLRLGLLCSFSTPQARPSMRKISQYLDGNASLPEM 629          

Query:   20 IFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLXXXXXXXXXXXXXXXXXXIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLE-NRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTG-LLASSHYVLGWSFNMSGEAQXXXXXXXXXXXRPKQNHTVLILCVTFAVVVVIMLIVFISF--YLVRKLKK-SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP---SPGGYDSKKGHGSGGINTIRFEDFVHSYPNS 667
            I F V ++ S     SQ   F F+GF  +   +SL G+A++  +GLL LTN T   +GHAFY +P+                   A +PEY  LGGHG AFV++P++ L G+   +YLGL N + NGN  NH+ AVE DT+   E  DI+DNHVG+++N + S  S  A Y+ + N     L + SG  +Q W++YD  + +L+V ++ +  +KP   ++++  +LS IL   M++GFS+STG  + +S YVLGWSF M+G A+           R     T   L +   V+ + +++V +S   Y +R+ +K ++++E  EL+ GPHRF +++L  AT GFRD+ELLG GGFGRVYKG L  +  QVAVKR+SHES+QG+REF++EI SIGRLRHRNLV LLG+CR +G+LL+VYDYMP GSLDKYL+ +P   L W +RF++IKGVASGLLYLHEEWEQ VIHRD+KA NVLLD ELNGRL DFGLA+LY+HGT+P TT VVGTLGYLAPE  +TGK T +TDVFA GA LLEVA GRRPI+P    E++ILVDWV+ RW                           LG         ARP+MRQVV++LEG V LP+++P   S  G   K  H  G      F+DF +SYP+S
Sbjct:    5 IVFLVRVLVSLAIADSQDLNFTFSGFQST--NLSLDGLAELTSNGLLRLTNETYHRTGHAFYPNPVTFKNSINSTAFTFSTTFVFAIIPEYATLGGHGFAFVIAPTRGLPGALRGEYLGLFNKTNNGNQTNHVVAVELDTISSSEFNDIDDNHVGIDINGLVSERSASAGYYSQLNGQFTNLTLISGHPMQVWMEYDGMEKQLNVTIAPIDVDKPSRPLVTLSRDLSPILNSSMYIGFSSSTGNSVFASQYVLGWSFKMNGLAEALSISRLPKLPRVGPKKTSKFLTIGLPVLCLSLVLVAVSSISYAIRRTRKFAEVLEDWELDYGPHRFKFKDLYTATKGFRDEELLGSGGFGRVYKGVLPTSKIQVAVKRVSHESRQGMREFVAEIVSIGRLRHRNLVPLLGYCRRKGELLLVYDYMPYGSLDKYLYGQPTVALNWSQRFRVIKGVASGLLYLHEEWEQVVIHRDVKASNVLLDGELNGRLGDFGLARLYDHGTDPQTTHVVGTLGYLAPEHARTGKATTSTDVFALGAFLLEVASGRRPIQPT---EDIILVDWVFIRW---------------------------LG---------ARPSMRQVVQFLEGNVPLPDILPLRLSASG--QKFSHHEG------FDDFAYSYPSS 613          

Query:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE 693
            MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE
Sbjct:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE 693          

Query:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQP 690
            MQKTSKRSHSNSFSIAKELIFFWVFLVFSSG VFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQY+GLLNASENGNS NHIFAVEFDTVKDLE GDINDNHVGVNVNSMKSIASTPAAYFLEN TKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLK+SDIIEA ELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQ TNTQVAVKRISHESKQGLREF+SEIASIGRLRHRNLV LLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGG NTIRFEDFVHSYPNSPYLDVEDRDVDIEA STKHLDQP
Sbjct:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGQVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYMGLLNASENGNSTNHIFAVEFDTVKDLEFGDINDNHVGVNVNSMKSIASTPAAYFLENGTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKESDIIEAFELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQSTNTQVAVKRISHESKQGLREFVSEIASIGRLRHRNLVPLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGTNTIRFEDFVHSYPNSPYLDVEDRDVDIEADSTKHLDQP 690          

Query:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE 693
            MQKTSKRSHSNSFSIAKELIFFWVFLVFSSG VFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLE                               TKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLK+SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLV LLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE
Sbjct:    1 MQKTSKRSHSNSFSIAKELIFFWVFLVFSSGQVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLE-------------------------------TKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKESDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVPLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE 662          

Query:   49 GNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE 693
            GNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQY+GLLNASENGNS NHIFAVEFDTVKDLE GDINDNHVGVNVNSMKSIASTPAAYFLEN TKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLK+SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPE+VPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE
Sbjct:  342 GNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYMGLLNASENGNSTNHIFAVEFDTVKDLEFGDINDNHVGVNVNSMKSIASTPAAYFLENGTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKESDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPELVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDVEDRDVDIEAGSTKHLDQPTAE 986          

Query:   52 MSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIG 405
            MSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLK+SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQG +  ++ +A I 
Sbjct:    1 MSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKESDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGNKMSLTGVADIA 354          

Query:   15 IAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLD--------VEDRDVDIEA 681
            +AK+L+FFWVFLV  S  VFSQLDQFIFNGFH +GN MSLTGVADI   GL+CLTNT+SRVSGHAFYSSP++FKNS +SKV SFS+AF  A VPEYPKLGGHGLAF LSPSK+LSG PSQYLGLLNA++NGNS NHIFAVEFDTVKDLE GDI+DNHVG+N+NSM S AS  AAYFLEN TK+EL +KSG  IQAWIDYDSA+NRL+VKLS  SEKPRSSILS DV+LS ILQD MFVGFSASTGLLASSHYVLGWSFNMSGEA+SLSL SLPSLPRPK+NHTVLILCVTF+ V+++M I+FISFYLVRKLK +DIIEA EL+IGPHRFSY+ELKKAT GFRDKELLGFGGFGRVYKGTL  TNTQVAVKRISHESKQGLREF+SEIASIGRLRHRNLV+LLGWCRCRGDLL+VYD+MPNGSLDKYLFDEPKRVL W+ERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRL DFGLAKLYEHG NP+TTRVVGTLGYLAPELT+TGKPT ++DVFAFGA LLEV CGR+PIEPKALPEELILVDWVWERWQSGA LEVVDPKLNG+FDELEAIVVIKLGLMCSNDA +ARPT+RQVVRYL GEVALPEVVPSPGG DS+KG+G  G     FED+VHSYP+S Y D         EDRDVDIEA
Sbjct:    1 MAKKLVFFWVFLV-CSDQVFSQLDQFIFNGFHEAGNNMSLTGVADIGSKGLICLTNTSSRVSGHAFYSSPVRFKNSSSSKVFSFSTAFAFAMVPEYPKLGGHGLAFTLSPSKELSGFPSQYLGLLNATDNGNSTNHIFAVEFDTVKDLEFGDIDDNHVGINLNSMVSNASASAAYFLENSTKQELSLKSGRMIQAWIDYDSARNRLEVKLSPFSEKPRSSILSFDVDLSPILQDSMFVGFSASTGLLASSHYVLGWSFNMSGEAESLSLLSLPSLPRPKENHTVLILCVTFSAVLIMMSIIFISFYLVRKLKNADIIEAWELDIGPHRFSYRELKKATRGFRDKELLGFGGFGRVYKGTLPSTNTQVAVKRISHESKQGLREFVSEIASIGRLRHRNLVQLLGWCRCRGDLLLVYDFMPNGSLDKYLFDEPKRVLSWEERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLGDFGLAKLYEHGQNPSTTRVVGTLGYLAPELTRTGKPTTSSDVFAFGAFLLEVVCGRKPIEPKALPEELILVDWVWERWQSGAVLEVVDPKLNGEFDELEAIVVIKLGLMCSNDALEARPTIRQVVRYLAGEVALPEVVPSPGGSDSRKGNGRRGAG---FEDYVHSYPDSSYFDKGSACSSAFEDRDVDIEA 671          

Query:   15 IAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGSPSQYLGLLNAS-ENGN-SANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYL---DVEDRDVDIEAGSTKHLD 688
            +AKELIFF VFLVFSS  VFS    FIFNGFH SG++MSL GVADI  +GLL LTN + R  G AFYSSP +FKNS N K  SFS+AF  A  P YP LGGHGLAFVLSPSK+++G  SQYLGLLN S  +GN S+N +FAVEFDTV  +E GD +DN+VG+++NSM S AS  A YFLEN   +EL +KSG  IQAWIDYDSA NRL+VKLS LS+KP+ SIL  DV+LS  L D MFVGFSASTG LAS HY+LGWSFNMSGEA+SLSL SLPSLPRPKQN+T LILCVTF  V+V+M IVFI FYLVR ++  D+IEA + EIGP RFSYQELKKAT GF+DKELLGFGGFGRVYKGTL  TNTQVAVKRISHESKQG+REF+SEI SIGRLRHRNLV+ LGWC+ R DLL+VYD+MP GSLDKYLFDEPK+VL W+ RFKIIKGVASGLLYLHEEWEQTVIHRDIKAGN+LLDSELNGRL DFGLAKLY+HG+NP +T VVGTLGYLAPELT+TGKP+ +TDVFAFGA+LLEVACGRRPI+PKAL EELILV+WV+E+WQSGA LEVVD KLNGDFDE EAI+VIKLGLMCSN+ P+ARPTM+QVVRYLEGEVALPE+VPSPGGYD K+G+ SG   +I FED+VHSY NS        ED+D+D+EAG T H++
Sbjct:    1 MAKELIFFLVFLVFSSNPVFSH---FIFNGFHDSGDQMSLNGVADITKNGLLRLTNISQRAIGRAFYSSPFQFKNSSNGKAFSFSTAFAFAMAPAYPTLGGHGLAFVLSPSKEIAGYHSQYLGLLNPSNHHGNKSSNPVFAVEFDTVSTIEFGDRDDNNVGIDLNSMHSNASVTAGYFLENSKVQELDLKSGKVIQAWIDYDSAINRLEVKLSTLSKKPKKSILHFDVDLSPFLHDSMFVGFSASTGKLASFHYILGWSFNMSGEAESLSLPSLPSLPRPKQNYTALILCVTFPAVLVMMSIVFIWFYLVRDMEDLDMIEAKDFEIGPQRFSYQELKKATRGFKDKELLGFGGFGRVYKGTLPTTNTQVAVKRISHESKQGIREFLSEIYSIGRLRHRNLVQFLGWCQRRRDLLLVYDFMPCGSLDKYLFDEPKQVLSWEHRFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNILLDSELNGRLGDFGLAKLYDHGSNPGSTTVVGTLGYLAPELTRTGKPSTSTDVFAFGALLLEVACGRRPIDPKALLEELILVEWVYEKWQSGAVLEVVDSKLNGDFDECEAILVIKLGLMCSNEVPEARPTMKQVVRYLEGEVALPELVPSPGGYDRKEGNRSG---SIAFEDYVHSYRNSSCACSSAFEDQDIDVEAGLTTHIN 673          

Query:   15 IAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGG-HGLAFVLSPSKQLSGSPSQYLGLLNASEN--GNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYL---DVEDRDVDIEAGSTKHLD 688
            +AKEL FFWV LVFSS  VFS    FIFNGFH SG++MSL GVA I  SGLL LTN T    G AFYSSP +FKNS N K  SFS+AF  A  P YP LGG HGLAFVLSPSKQ++G  SQYLGL N S++   NS+NH+FAVEFDT ++LE GD +DNHVG++++SM S AS  A YFLEN T ++L + SG  IQAWIDYDSA NRL+VKLS LS+KP+ SILS  V+LS  L D MFVGFSASTG LASSHY+LGWSFNMSGEA+SLSL SLPSLPRPKQN+T LILCV F  V++++ + FISFYLVR +K  D+IEA +LEIGP RFSYQELKKAT GF+DKELLGFGGFGRVYKGTL  TNTQVAVKRISHESKQG+REF+SEI SIGRLRHRNLV+ LGWC+CRGDLL+VYD+MP GSLDKYLFDEPK+VL W+ RFKIIKGVASGLLYLHEEWEQTVIHRDIKAGN+LLDSELNGRL DFGLAKLY+HG+NP +T VVGT GYLAPEL +TGKP+ +TDVFAFGA+LLEVACGRRPI+PKALPEELILV+WV+E+WQSGA LEVVD KL GDFDE EAI+VIKLGLMCSN+ P+ARPTM+QVVRYLEGEVALP++VPSPGGY   +G+ S   ++I FED+VHSY NS        E++D+D+EAG T H++
Sbjct:    1 MAKELFFFWVSLVFSSNPVFSH---FIFNGFHDSGDQMSLNGVAGITKSGLLRLTNITQDAIGRAFYSSPFQFKNSSNGKAFSFSTAFAFAMAPAYPTLGGGHGLAFVLSPSKQIAGYHSQYLGLHNPSDHHGNNSSNHVFAVEFDTWRNLEFGDKDDNHVGIDLSSMHSNASATAGYFLENSTMQKLNLNSGKVIQAWIDYDSAINRLEVKLSTLSKKPKKSILSFGVDLSPFLHDSMFVGFSASTGKLASSHYLLGWSFNMSGEAESLSLPSLPSLPRPKQNYTALILCVIFPAVLLMISLAFISFYLVRNMKNLDMIEAKDLEIGPQRFSYQELKKATKGFKDKELLGFGGFGRVYKGTLPTTNTQVAVKRISHESKQGIREFLSEIYSIGRLRHRNLVQFLGWCQCRGDLLLVYDFMPCGSLDKYLFDEPKQVLSWEHRFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNILLDSELNGRLGDFGLAKLYDHGSNPGSTTVVGTFGYLAPELPRTGKPSTSTDVFAFGALLLEVACGRRPIDPKALPEELILVEWVYEKWQSGAVLEVVDSKLKGDFDECEAILVIKLGLMCSNEVPEARPTMKQVVRYLEGEVALPKLVPSPGGYGRNEGNRS---DSIAFEDYVHSYRNSSSACSSAFENQDIDVEAGLTTHIN 674          

Query:   15 IAKELIFFWVFLVFSSGHVFSQLDQFIFNGFH--GSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSD-NSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSG---GINTIRFEDFVHSYPNSPYLDV--------EDRDVDIEAGSTKHL 687
            +AK+L FF V  +F +  VFSQ ++F F+GF    + N MSL G A+I  +G L LTNTT RV GHAFYSSP+KFKNS  N+K  SFS+ F  A VPEY  LGGHG AF +S SK+L G+ PSQYLGLLN+S+ GN  NHIFAVEFDTVKD E GDINDNHVG+++NS++S AS PAAYFLEN TK+ L +KSG  IQAWIDYDS+KN L+V+L+  S KPRS ILS DV+LS I+++ M+VGFS+STGLLASSHY+LGWSFNMSG+A+SLSL SLPSLPRPK+ H  LI+ VT +   V+ L + +  YLV+K++ +D++E+ EL++GPHRFSY+ELKKAT GFRDKELLGFGGFGRVYKGTL  TNTQVAVKR+S+ESKQGLREF SEI+SIGRLRHRNLV+LLGWCR RGDLL+VYD+MPNGSLDK LFDE K +L W++R++IIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRL DFGLAKLYE GTNP+TTRVVGTLGYLAPELT+TGKPT ++DV+AFGA+LLEV CGRRPIEPKALPEELILVDWVW+RW++GA LEVVDP+LNG+F+E+EA+ V+KLGLMCSNDA +ARPTMRQVVRYLEGEV LP+ V +P   D KK   SG   G++   FEDFV+SYPNS  L+         +D DVDIEAGS+  L
Sbjct:    1 MAKKLKFFLVLFIFLANPVFSQQEEFFFSGFRDAANNNNMSLNGAAEIEKNGKLMLTNTTLRVLGHAFYSSPIKFKNSTRNNKSLSFSTCFAFAIVPEYTALGGHGFAFTISASKELPGTLPSQYLGLLNSSDLGNLTNHIFAVEFDTVKDFEFGDINDNHVGIDINSLRSNASEPAAYFLENSTKQVLNLKSGEVIQAWIDYDSSKNHLEVRLAPSSVKPRSPILSFDVDLSPIVKETMYVGFSSSTGLLASSHYILGWSFNMSGDAKSLSLDSLPSLPRPKEKHLGLIVGVTVSAFFVMFLAIAVGCYLVKKIRNADVLESWELDVGPHRFSYEELKKATRGFRDKELLGFGGFGRVYKGTLPSTNTQVAVKRVSNESKQGLREFASEISSIGRLRHRNLVQLLGWCRRRGDLLLVYDFMPNGSLDKCLFDEQKAILTWEQRYRIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLGDFGLAKLYERGTNPSTTRVVGTLGYLAPELTRTGKPTTSSDVYAFGALLLEVVCGRRPIEPKALPEELILVDWVWDRWKAGAILEVVDPRLNGEFNEIEALDVVKLGLMCSNDAAEARPTMRQVVRYLEGEVPLPQAVAAPDACDGKKEKTSGGGAGVDGPEFEDFVYSYPNSSLLEKVSNWSSAGDDADVDIEAGSSSPL 688          

Query:   12 SFSIAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNK---MSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDV----------EDRDVDIEA 681
            SF   +++  + +FLV +   VFSQLD+FIF+GF G+ N    +SL G A I + G+L LT+ T RV GHAFYSSP++FKNS ++K  SFS+AF  A +P+YPKLGGHGLAF +SP+K+L+G+ PSQYLGL NA+  GN  N +FAVEFDTV+D E GDINDNHVG+++NS+ S  S PAAYFL+N TK++L +K G  IQAWIDYDS  NR+DVKLSL S KPR SILS DV+LS IL+D MFVGFS+STGLLAS HY+LGWSFNMSGEAQSLSLS LPSLP PK++   LI+ VT +   V++L++ ++F+L+RK+K +DIIE  EL++GPHRF+YQELKKAT GFRDKELLG GGFGRVYKGTL  T+TQVAVKR+SHESKQGLREF+SEIASIGRLRHRNLV+L+GWCR RGDLL+VYD+MPNGSLDKYLF+EPK +L W++RFKIIK VASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRL DFGLAKL+EHG+NP+TTRVVGTLGYLAPELT+TGKPT ++DVFAFGA+LLEV CGR+PIEPKALPEELILVDWVW++W+SGA L+VVDP+LNG+FDE+EA+VV+KLGL+CSND P+ARPTMRQVVRYLEGEV LPEVV +P  Y+ KKG+GSG    + +ED+VHSY  S YL+           ED  VDIEA
Sbjct:    1 SFMAQRKVTLWVLFLVLNP--VFSQLDEFIFSGFSGAKNNNHSLSLNGAAGIENKGILRLTDDTLRVLGHAFYSSPIQFKNSTSNKAVSFSTAFAFACIPQYPKLGGHGLAFTISPTKELAGALPSQYLGLFNANNIGNFTNDVFAVEFDTVQDFEFGDINDNHVGIDINSLISNKSVPAAYFLDNSTKQDLYMKGGEVIQAWIDYDSTINRIDVKLSLSSIKPRYSILSFDVDLSPILKDTMFVGFSSSTGLLASYHYILGWSFNMSGEAQSLSLSDLPSLPGPKKSQLPLIIGVTVSACFVVILVIAVAFFLIRKIKNADIIEQWELDVGPHRFTYQELKKATRGFRDKELLGLGGFGRVYKGTLPNTDTQVAVKRVSHESKQGLREFVSEIASIGRLRHRNLVQLVGWCRQRGDLLLVYDFMPNGSLDKYLFNEPKAILSWEQRFKIIKDVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLGDFGLAKLFEHGSNPSTTRVVGTLGYLAPELTRTGKPTTSSDVFAFGALLLEVVCGRKPIEPKALPEELILVDWVWDKWRSGAVLDVVDPRLNGEFDEIEAVVVVKLGLICSNDLPEARPTMRQVVRYLEGEVPLPEVVAAPNVYEGKKGNGSGVGGGVEYEDYVHSYGISSYLEKICTWSSAGEGEDGVVDIEA 682          

Query:   15 IAKELIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKGHGSGGINTIRFEDFVHSYPNSPYLDV-------EDRDVDIEAGST 684
            +A+ L+  WVF V S     S  D+  FNGF G+ + MSL G + I D+G+L LTN T RV GHAFY  P++FKNS + K  SFS+AF  A VPEY  LGGHGLAF +SP+K+L G+ P QYLGLLNASE GN +NHIFAVEFDTV+DLE  DINDNHVG++++S+ S  S PAAYF  N + +EL +KSG  IQAWI+Y+S  NRLDVKLS  S KPRS++LS +V+LS  LQ+FM+VGFS+STGLLASSH+++GWS  M+GEA++L L  LPSLPRPK+NH  LI+ V+  V ++++ ++ +SF L+RK+K +D++EA EL++GPHRFSY+ELKKAT  FRDKELLGFGGFGRVYKGTL  +NTQVAVKRISHESKQGLREF+SEIASIGRLRHRNLV+LLGWCR RGDLL+VYD+MPNGSLDKYLFDEPK +L WD+RFKIIK VASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRL DFGLAKLYEHG+NP+TT+VVGTLGYLAPELT+TGKPT ++DVFAFGA+LLEV CGRRPIEPKALPEELILVDWVW+ W+ GA LEVVDP++ G+FDELEA+VV+KLGLMCSN++P ARPTMRQV RYLEGEVALPE V +   YD KKG G         ED+V +  +S +  V       +D D DIEAGS+
Sbjct:    1 MAERLVLLWVFSVLSI-PARSVFDELFFNGFKGAASNMSLNGASGIQDNGILRLTNETQRVLGHAFYPLPIQFKNSTDGKALSFSTAFAFAIVPEYATLGGHGLAFAISPTKELLGTLPRQYLGLLNASEVGNFSNHIFAVEFDTVQDLEFEDINDNHVGIDIDSLVSNKSVPAAYFDGNNSLQELNLKSGQVIQAWIEYNSQNNRLDVKLSPSSVKPRSTLLSFEVDLSPFLQEFMYVGFSSSTGLLASSHFIMGWSLKMNGEAKTLKLDDLPSLPRPKENHKSLIIGVS--VSLLMIFVIVLSFRLIRKIKNADVVEAWELDVGPHRFSYKELKKATRSFRDKELLGFGGFGRVYKGTLPSSNTQVAVKRISHESKQGLREFVSEIASIGRLRHRNLVQLLGWCRRRGDLLLVYDFMPNGSLDKYLFDEPKTILSWDQRFKIIKDVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLGDFGLAKLYEHGSNPSTTKVVGTLGYLAPELTRTGKPTTSSDVFAFGALLLEVVCGRRPIEPKALPEELILVDWVWDNWRVGAILEVVDPRIGGEFDELEAVVVLKLGLMCSNNSPKARPTMRQVARYLEGEVALPESVEALDAYDEKKGGG-------ELEDYVXT--SSIFEKVSTRSSVNDDMDADIEAGSS 666          

Query:   33 VFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRP----KQNHTVLILCVTFAVVVVIM-LIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDE-PKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKG------HGSGGINTIRFEDFVHS 663
            V S +  F F GF  +   ++L GVA+IA +G + LT  T RV GHAFYS P++FK    ++  SFS++F IA VPE+  LGGHGLAF ++P+  L GS PSQYLGLLN+S   N ++H FAVEFDTV+DLE  DINDNHVG+++NSM+S  STPA YFL N TK+EL +  G  IQAWIDYDS K RLDVKLS  SEKP+ S+LS DV+LSS+L D M+VGFSASTGLLASSHY+LGW+FNMSGEA SLSL SLP +P      K+    LIL V+    ++I  ++V  S ++VRK+K  D +E  EL+ GPHRFSY+ELKKAT GF DKELLG GGFG+VYKG L G++  VAVKRISHES+QG+REFMSE++SIG LRHRNLV+LLGWCR R DLL+VYD+MPNGSLD YLFDE P+ +L W +RFKIIKGVASGLLYLHE WEQTVIHRDIKA NVLLDSE+NGR+ DFGLAKLYEHG++P  TRVVGT GYLAPELTK+GK T +TDV+AFGAVLLEVACGRRPIE  ALPEEL++VDWVW RWQSG   +VVD +LNG+FDE E ++VIKLGL+CSN++P+ RPTMRQVV YLE +   PEVVP+P   D+          GS G     FEDFV S
Sbjct:   19 VSSLIQDFSFIGFKKASPNLTLNGVAEIAPTGAIRLTTETQRVIGHAFYSLPIRFKPIGVNRALSFSTSFAIAMVPEFVTLGGHGLAFAITPTPDLRGSLPSQYLGLLNSSRV-NFSSHFFAVEFDTVRDLEFEDINDNHVGIDINSMESSISTPAGYFLANSTKKELFLDGGRVIQAWIDYDSNKKRLDVKLSPFSEKPKLSLLSYDVDLSSVLGDEMYVGFSASTGLLASSHYILGWNFNMSGEAFSLSLPSLPRIPSSIKKRKKKRQSLILGVSLLCSLLIFAVLVAASLFVVRKVKDEDRVEEWELDFGPHRFSYRELKKATNGFGDKELLGSGGFGKVYKGKLPGSDEFVAVKRISHESRQGVREFMSEVSSIGHLRHRNLVQLLGWCRRRDDLLLVYDFMPNGSLDMYLFDENPEVILTWKQRFKIIKGVASGLLYLHEGWEQTVIHRDIKAANVLLDSEMNGRVGDFGLAKLYEHGSDPGATRVVGTFGYLAPELTKSGKLTTSTDVYAFGAVLLEVACGRRPIETSALPEELVMVDWVWSRWQSGDIRDVVDRRLNGEFDEEEVVMVIKLGLLCSNNSPEVRPTMRQVVMYLEKQFPSPEVVPAPDFLDANDSMCLDERSGSAG----EFEDFVDS 657          

Query:   35 SQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLL-SEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPR--PKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKK-SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIE-PKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAI-VVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP 636
            SQ   F +NGFH     +SL G+A +  +GLL LTNT+ + +GHAF +  ++FK+S N  VSSFS+ FV A   + P L GHG+AFV++P+  L  + PSQY+GL N S NGN  NHIFAVEFDT++  E GD NDNHVG+++N ++S   + A Y  ++   + L + S  +IQ WIDYD+  +R+DV ++   S+KPR  ++S   +LSSIL + M+VGFS++TG + S H+++GWSF ++GEA  LSLS LP LPR  P++      + +    + +I  I+F++FY+VR+ KK  + ++  E E G +RF ++EL  AT GF++K+LLG GGFGRVY+G L  T  +VAVKR+SH+SKQG++EF++EI SIGR+ HRNLV LLG+CR RG+LL+VYDYMPNGSLDKYL++ P+  L W +R  IIKGVASGL YLHEEWEQ VIHRD+KA NVLLD++ NGRL DFGLA+LY+HG++P TT VVGTLGYLAPE ++TG+ T  TDV+AFGA LLEV  GRRPIE   A  +  +LV+WV+  W  G  +E  DPKL     +LE + +V+KLGL+CS+  P ARP+MRQV++YL G++ALPE+ P
Sbjct:   22 SQNLNFTYNGFHPPLTDISLQGLATVTPNGLLKLTNTSVQKTGHAFCTERIRFKDSQNGNVSSFSTTFVFAIHSQIPTLSGHGIAFVVAPTLGLPFALPSQYIGLFNISNNGNDTNHIFAVEFDTIQSSEFGDPNDNHVGIDLNGLRSANYSTAGYRDDHDKFQNLSLISRKRIQVWIDYDNRSHRIDVTVAPFDSDKPRKPLVSYVRDLSSILLEDMYVGFSSATGSVLSEHFLVGWSFRLNGEAPMLSLSKLPKLPRFEPRRISEFYKIGMPLISLSLIFSIIFLAFYIVRRKKKYEEELDDWETEFGKNRFRFKELYHATKGFKEKDLLGSGGFGRVYRGILPTTKLEVAVKRVSHDSKQGMKEFVAEIVSIGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYNNPETTLDWKQRSTIIKGVASGLFYLHEEWEQVVIHRDVKASNVLLDADFNGRLGDFGLARLYDHGSDPQTTHVVGTLGYLAPEHSRTGRATTTTDVYAFGAFLLEVVSGRRPIEFHSASDDTFLLVEWVFSLWLRGNIMEAKDPKLGSSGYDLEEVEMVLKLGLLCSHSDPRARPSMRQVLQYLRGDMALPELTP 630          

Query:   35 SQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLS-GSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSE-KPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPR--PKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKK-SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIE-PKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP 636
            SQ   F +N        +S+ G+  +  +GLL LTNTT + +GHAFY+ P++FK+S N  VSSFS++FV A   +   L GHG+AFV++P+  L  G+PSQY+GL N + NGN  NH+FAVE DT+   E  D NDNHVG+++NS+KS+ S+PA Y+ E    + L + S   +Q W+DYD   N++DV ++  +E KP   +++   +LSS+L   M+VGFS++TG + S HY+LGWSF ++ +A  L+LS LP LPR  PK+      + +    + +I   +F+  Y+VR+ +K ++ +E  E E G +RF +++L  AT GF++K LLG GGFG VYKG + GT  ++AVKR+SHES+QG++EF++EI SIGR+ HRNLV LLG+CR RG+LL+VYDYMPNGSLDKYL++ P+  L W +R K+I GVASGL YLHEEWEQ VIHRD+KA NVLLD ELNGRL DFGLA+LY+HG++P TT VVGTLGYLAPE T+TG+ T+ATDVFAFGA LLEVACGRRPIE  +   E  +LVDWV+  W  G  L   DP +  + DE E  +V+KLGL+CS+  P ARP+MRQV+ YL G+  LPE+ P
Sbjct:   22 SQSLNFAYNNGFNPPTDLSIQGITTVTPNGLLKLTNTTVQKTGHAFYTKPIRFKDSPNGTVSSFSTSFVFAIHSQIAILSGHGIAFVVAPNASLPYGNPSQYIGLFNLANNGNETNHVFAVELDTILSTEFNDTNDNHVGIDINSLKSVQSSPAGYWDEKGQFKNLTLISRKPMQVWVDYDGRTNKIDVTMAPFNEDKPTRPLVTAVRDLSSVLLQDMYVGFSSATGSVLSEHYILGWSFGLNEKAPPLALSRLPKLPRFEPKRISEFYKIGMPLISLFLIFSFIFLVCYIVRRRRKFAEELEEWEKEFGKNRFRFKDLYYATKGFKEKGLLGTGGFGSVYKGVMPGTKLEIAVKRVSHESRQGMKEFVAEIVSIGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYNTPEVTLNWKQRIKVILGVASGLFYLHEEWEQVVIHRDVKASNVLLDGELNGRLGDFGLARLYDHGSDPQTTHVVGTLGYLAPEHTRTGRATMATDVFAFGAFLLEVACGRRPIEFQQETDETFLLVDWVFGLWNKGDILAAKDPNMGSECDEKEVEMVLKLGLLCSHSDPRARPSMRQVLHYLRGDAKLPELSP 629          

Query:   19 LIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLS-GSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSE-KPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLP-------RPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALP-EELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP 636
            L FFW  L  SS     Q+  F +NGF      +S+ G+A I  +GLL LTNTT + +GHAFY+ P++FK+S N  VSSFS+ FV A   + P    HG+AFV++P+ +L  GSP QYLGL N + NGN  NH+FAVE DT+ ++E  D N+NHVG+++NS+ S+ S+PA Y+ EN     L + S  ++Q W+D+D   + +DV ++   E KPR  ++SI  +LSS+L   MFVGFS++TG + S  +VLGWSF ++GEAQ L+LS LP LP       R  + +   +  ++  ++  +++I  + F + R+ K ++ +E  E E G +R  +++L  AT GF+DK +LG GGFG VYKG +  T  ++AVKR+S+ES+QGL+EF++EI SIG++ HRNLV L+G+CR R +LL+VYDYMPNGSLDKYL++ P+  L W +RFK+I GVAS L YLHEEWEQ VIHRD+KA NVLLD+ELNGRL DFGLA+L +HG++P TTRVVGT GYLAP+  +TG+ T  TDVFAFG +LLEVACGRRPIE      E ++LVDWV+  W     L+  DP L  ++D+ E  +V+KLGL+CS+  P ARPTMRQV++YL G+  LP++ P
Sbjct:   12 LSFFWQSLKSSS-----QIIDFTYNGFRPPPTDISILGIATITPNGLLKLTNTTMQSTGHAFYTKPIRFKDSPNGTVSSFSTTFVFAIHSQIPI--AHGMAFVIAPNPRLPFGSPLQYLGLFNVTNNGNVRNHVFAVELDTIMNIEFNDTNNNHVGIDINSLNSVKSSPAGYWDENDQFHNLTLISSKRMQVWVDFDGPTHLIDVTMAPFGEVKPRKPLVSIVRDLSSVLLQDMFVGFSSATGNIVSEIFVLGWSFGVNGEAQPLALSKLPRLPVWDLKPTRVYRFYKNWVPLISLLLIPFLLIIFLVRFIMKRRRKFAEEVEDWETEFGKNRLRFKDLYYATKGFKDKNILGSGGFGSVYKGIMPKTKKEIAVKRVSNESRQGLKEFVAEIVSIGQMSHRNLVPLVGYCRRRDELLLVYDYMPNGSLDKYLYNSPEVTLDWKQRFKVINGVASALFYLHEEWEQVVIHRDVKASNVLLDAELNGRLGDFGLAQLCDHGSDPQTTRVVGTWGYLAPDHIRTGRATTTTDVFAFGVLLLEVACGRRPIEINNQSGERVVLVDWVFRFWMEANILDAKDPNLGSEYDQKEVEMVLKLGLLCSHSDPLARPTMRQVLQYLRGDAMLPDLSP 632          

Query:   35 SQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSE-KPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGE-AQSLSLSSLPSLPR--PK------QNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEE-LILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP 636
            SQ   F +N FH     +S+ G+A +  +G+L LT+ T   +GHAFY+ P++FK+S N  VSSFS+ FVI      P + GHG+AF ++P+  LS +  SQYLGL +++ NGN  NHI AVEFDT+ + E  D NDNHVG+N+NS+ S+ S+   Y+ E      L + S  ++Q W+DYD   N++DV ++   E KPR +++S+  +LSS+    M++GFSA+TG + S H+V GWSF + G+ A  L+LS +P  PR  P       +N   L   +   V+ V+ LI  + F + R+ K ++  E  E E G +R  +++L  AT GF+DK+LLG GGFGRVY+G +  T  ++AVKR+S+ES+QGL+EF++EI SIGR+ HRNLV LLG+CR R +LL+VYDYMPNGSLDKYL+D P+  L W +RF +I GVASGL YLHEEWEQ VIHRDIKA NVLLD+E NGRL DFGLA+L +HG++P TTRVVGT GYLAP+  +TG+ T ATDVFAFG +LLEVACGRRPIE +   +E ++LVD V+  W  G  L+  DP L   +D+ E   V+KLGL+CS+  P  RPTMRQV++YL G+  LP++ P
Sbjct:   24 SQSLNFTYNSFHRPPTNISIQGIATVTSNGILKLTDKTVISTGHAFYTEPIRFKDSPNDTVSSFSTTFVIGIYSGIPTISGHGMAFFIAPNPVLSSAMASQYLGLFSSTNNGNDTNHILAVEFDTIMNPEFDDTNDNHVGININSLTSVKSSLVGYWDEINQFNNLTLISRKRMQVWVDYDDRTNQIDVTMAPFGEVKPRKALVSVVRDLSSVFLQDMYLGFSAATGYVLSEHFVFGWSFMVKGKTAPPLTLSKVPKFPRVGPTSLQRFYKNRMPLFSLLLIPVLFVVSLIFLVRFIVRRRRKFAEEFEDWETEFGKNRLRFKDLYYATKGFKDKDLLGSGGFGRVYRGVMPTTKKEIAVKRVSNESRQGLKEFVAEIVSIGRMSHRNLVPLLGYCRRRDELLLVYDYMPNGSLDKYLYDCPEVTLDWKQRFNVIIGVASGLFYLHEEWEQVVIHRDIKASNVLLDAEYNGRLGDFGLARLCDHGSDPQTTRVVGTWGYLAPDHVRTGRATTATDVFAFGVLLLEVACGRRPIEIEIESDESVLLVDSVFGFWIEGNILDATDPNLGSVYDQREVETVLKLGLLCSHSDPQVRPTMRQVLQYLRGDATLPDLSP 637          

Query:   35 SQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLS-GSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENR-TKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVL-ILCVTFAVV-VVIMLIVFISFYLVRKLKK-SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKA-LPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIV--VIKLGLMCSNDAPDARPTMRQVVRYLEGEVALP 632
            S+  +F FNG+         +G+A     GL+ LTN++    GH FY+SP++FKNS N  VSSFS+ FV A V     L GHGLAFV+SP+K L   S SQYLGL N + NG+ +NHI AVEFDT ++ E  D+++NHVG+++NS+ S  ++ A Y+ ++  T + + + +   IQAWI+YDS++ +L+V +  +   KP+  +LS+  +LS  L D M+VGF+++TG L SSHY+LGW+F ++G A ++ +S LP LPR  ++ +V  IL ++ ++  + I++ + IS+ L  K KK  +++E  E++ GPHRF+Y++L  AT GFR+ ELLG GGFG+VYKGTL  +N  +AVK++SH+S+QG+REF++EIA+IGRLRH NLVRLLG+CR +G+L +VYD MP GSLDK+L+ +P++ L W +RFKIIK VASGL YLH +W Q +IHRDIK  NVLLD  +NG+L DFGLAKL EHG +P T+ V GT GY++PEL++TGK + ++DVFAFG ++LE+ CGRRP+ P+A  P E++L DWV + W+    L+VVD ++  D   LE  V  V+KLGL CS+     RP+M  V+++L+G   LP
Sbjct:   37 SEEGEFGFNGYLYDN-----SGIAITNSKGLMKLTNSSEFSYGHVFYNSPVRFKNSPNGTVSSFSTTFVFAIVSNVNALDGHGLAFVISPTKGLPYSSSSQYLGLFNLTNNGDPSNHIVAVEFDTFQNQEFDDMDNNHVGIDINSLSSEKASTAGYYEDDDGTFKNIRLINQKPIQAWIEYDSSRRQLNVTIHPIHLPKPKIPLLSLTKDLSPYLFDSMYVGFTSATGRLRSSHYILGWTFKLNGTASNIDISRLPKLPRDSRSTSVKKILAISLSLTSLAILVFLTISYMLFLKRKKLMEVLEDWEVQFGPHRFAYKDLYIATKGFRNSELLGKGGFGKVYKGTLSTSNMDIAVKKVSHDSRQGMREFVAEIATIGRLRHPNLVRLLGYCRRKGELYLVYDCMPKGSLDKFLYHQPEQSLDWSQRFKIIKDVASGLCYLHHQWVQVIIHRDIKPANVLLDDSMNGKLGDFGLAKLCEHGFDPQTSNVAGTFGYISPELSRTGKASTSSDVFAFGILMLEITCGRRPVLPRASSPSEMVLTDWVLDCWEDD-ILQVVDERVKQDDKYLEEQVALVLKLGLFCSHPVAAVRPSMSSVIQFLDGVAQLP 637          

Query:   35 SQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLS-GSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENR-TKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVL-ILCVTFAVV-VVIMLIVFISFYLVRKLKK-SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKA-LPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIV--VIKLGLMCSNDAPDARPTMRQVVRYLEGEVALP 632
            S+  +F FNG+         +G+A     GL+ LTN++    GH FY+SP++FKNS N  VSSFS+ FV A V     L GHGLAFV+SP+K L   S SQYLGL N + NG+ +NHI AVEFDT ++ E  D+++NHVG+++NS+ S  ++ A Y+ ++  T + + + +   IQAWI+YDS++ +L+V +  +   KP+  +LS+  +LS  L D M+VGF+++TG L SSHY+LGW+F ++G A ++ +S LP LPR  ++ +V  IL ++ ++  + I++ + IS+ L  K KK  +++E  E++ GPHRF+Y++L  AT GFR+ ELLG GGFG+VYKGTL  +N  +AVK++SH+S+QG+REF++EIA+IGRLRH NLVRLLG+CR +G+L +VYD MP GSLDK+L+ +P++ L W +RFKIIK VASGL YLH +W Q +IHRDIK  NVLLD  +NG+L DFGLAKL EHG +P T+ V GT GY++PEL++TGK + ++DVFAFG ++LE+ CGRRP+ P+A  P E++L DWV + W+    L+VVD ++  D   LE  V  V+KLGL CS+     RP+M  V+++L+G   LP
Sbjct:   23 SEEGEFGFNGYLYDN-----SGIAITNSKGLMKLTNSSEFSYGHVFYNSPVRFKNSPNGTVSSFSTTFVFAIVSNVNALDGHGLAFVISPTKGLPYSSSSQYLGLFNLTNNGDPSNHIVAVEFDTFQNQEFDDMDNNHVGIDINSLSSEKASTAGYYEDDDGTFKNIRLINQKPIQAWIEYDSSRRQLNVTIHPIHLPKPKIPLLSLTKDLSPYLFDSMYVGFTSATGRLRSSHYILGWTFKLNGTASNIDISRLPKLPRDSRSTSVKKILAISLSLTSLAILVFLTISYMLFLKRKKLMEVLEDWEVQFGPHRFAYKDLYIATKGFRNSELLGKGGFGKVYKGTLSTSNMDIAVKKVSHDSRQGMREFVAEIATIGRLRHPNLVRLLGYCRRKGELYLVYDCMPKGSLDKFLYHQPEQSLDWSQRFKIIKDVASGLCYLHHQWVQVIIHRDIKPANVLLDDSMNGKLGDFGLAKLCEHGFDPQTSNVAGTFGYISPELSRTGKASTSSDVFAFGILMLEITCGRRPVLPRASSPSEMVLTDWVLDCWEDD-ILQVVDERVKQDDKYLEEQVALVLKLGLFCSHPVAAVRPSMSSVIQFLDGVAQLP 623          

Query:   45 FHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKL-SLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQN-----HTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPE 633
            F+ SGN M  +G A I ++GL+ LTN+T + +G  FY+  L+FKNS N  VSSFS+ FV +        GG+G+AFV+ P++ LS + P+ YLGL N S  G+  NHI AVE DT  D +  D + NHVG+++N++ S     A Y+++N T   L++ SG  +Q WI+YDS + +++V L  L   KP+  +LS++ +LS  L + M+VGF+++TG L +SHY+LGW+F M+G    +  S LP +PR  Q      + +L + +T + V++++++    +  +++ K  +++E  E++ GPHRF++++L  AT GF+D E+LG GGFG+VYKGTL  +N ++AVK +SH+S+QG+REF++EIA+IGRLRH NLVRL G+CR +G+L +VYD M  GSLDK+L+ +    L W +RFKIIK VASGL YLH++W Q +IHRDIK  N+LLD+ +N +L DFGLAKL +HGT+P T+ V GTLGY++PEL++TGK +  +DVFAFG V+LE+ACGR+PI P+A   E++L DWV E W++   ++V+D K+  ++ E +A +V+KLGL CS+     RP M  V++ L+    LP 
Sbjct:   28 FNTSGN-MYTSGSAYINNNGLIRLTNSTPQTTGQVFYNDQLRFKNSVNGTVSSFSTTFVFSIEFHNGIYGGYGIAFVICPTRDLSPTFPTTYLGLFNRSNMGDPKNHIVAVELDTKVDQQFEDKDANHVGIDINTLVSDTVALAGYYMDNGTFRSLLLNSGQPMQIWIEYDSKQKQINVTLHPLYVPKPKIPLLSLEKDLSPYLLELMYVGFTSTTGDLTASHYILGWTFKMNGTTPDIDPSRLPKIPRYNQPWIQSPNGILTISLTVSGVIILIILSLSLWLFLKRKKLLEVLEDWEVQFGPHRFAFKDLHIATKGFKDTEVLGKGGFGKVYKGTLPVSNVEIAVKMVSHDSRQGMREFIAEIATIGRLRHPNLVRLQGYCRHKGELYLVYDCMAKGSLDKFLYHQQTGNLDWSQRFKIIKDVASGLYYLHQQWVQVIIHRDIKPANILLDANMNAKLGDFGLAKLCDHGTDPQTSHVAGTLGYISPELSRTGKASTRSDVFAFGIVMLEIACGRKPILPRASQREMVLTDWVLECWENEDIMQVLDHKIGQEYVEEQAALVLKLGLFCSHPVAAIRPNMSSVIQLLDSVAQLPH 622          

Query:   15 IAKELIFFWVFLVFS--SGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLS-GSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELI-IKSGAKIQAWIDYDSAKNRLDVKLSLL-SEKPRSSILSIDVNLSSIL-QDFMFVGFSASTGLLASSHYVLGWSFNMSGE-AQSLSLSSLPSLPRPKQNHTVLILCVTFA---VVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP 636
            ++K L   W+   F   S    S+   F+FNGF G  N ++L G A +  +GLL L   +    GHAF   P+ F    +SK  SFS+ FV A VP+    GGHG+ FV+SP+   +   P++Y+G+ NAS NG+ ++H+FAVE DTV++ +  + N+NH+G++VN+  S+ S PA+YF +   K   I + SG  IQ W+DY    N L+V ++ L +EKP   +LS  +NLS I  +  +FVGF+A+TG   S HY+LGWSF+ + E +Q L  S LP +PRP+  H  +   +  A   ++ ++++ V    Y  RK K +++ E  E + G HRFSY+ L  AT GF     LG GGFG VY+G L   N  VAVKR+SH+ +QG+++F++E+ S+  L+HRNLV LLG+CR +G+LL+V +YMPNGSLD++LFD+   VL W +RF I+KG+AS L YLH E EQ V+HRDIKA NV+LD+ELNGRL DFG+A+ ++HG N  TT  VGT+GY+APEL   G  TI TDV+AFG  LLEVACGR+P+E     E+  L+ WV E W+  + L+  DP+L  +F   E  +V+KLGL+C+N  P++RP M QVV YL G + LP+  P
Sbjct:    1 MSKGLFLIWLISSFHLISFSTSSKDTSFVFNGF-GQSN-LALDGSATLLPNGLLQLAKDSQHQMGHAFIKKPIDF---SSSKPLSFSTHFVCALVPKPGFEGGHGITFVISPTVDFTRAQPTRYMGIFNASTNGSPSSHLFAVELDTVRNPDFRETNNNHIGIDVNNPISVESAPASYFSKTAQKNVSINLSSGKPIQVWVDYHG--NVLNVSVAPLEAEKPSLPLLSRSMNLSEIFSRRRLFVGFAAATGTSISYHYLLGWSFSTNRELSQLLDFSKLPQVPRPRAEHKKVQFALIIALPVILAIVVMAVLAGVYYHRKKKYAEVSEPWEKKYGTHRFSYKSLYIATKGFHKDRFLGRGGFGEVYRGDLP-LNKTVAVKRVSHDGEQGMKQFVAEVVSMKSLKHRNLVPLLGYCRRKGELLLVSEYMPNGSLDQHLFDDQSPVLSWSQRFVILKGIASALFYLHTEAEQVVLHRDIKASNVMLDAELNGRLGDFGMARFHDHGGNAATTAAVGTVGYMAPELITMGASTI-TDVYAFGVFLLEVACGRKPVEFGVQVEKRFLIKWVCECWKKDSLLDAKDPRLGEEFVPEEVELVMKLGLLCTNIVPESRPAMGQVVLYLSGNLPLPDFSP 623          

Query:   15 IAKELIFFWVFLVFS--SGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLS-GSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELI-IKSGAKIQAWIDYDSAKNRLDVKLSLL-SEKPRSSILSIDVNLSSIL-QDFMFVGFSASTGLLASSHYVLGWSFNMSGE-AQSLSLSSLPSLPRPKQNHTVLILCVTFA---VVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP 636
            ++K L   W+   F   S    S+   F+FNGF G  N ++L G A +  +GLL L   +    GHAF   P+ F    +SK  SFS+ FV A VP+    GGHG+ FV+SP+   +   P++Y+G+ NAS NG+ ++H+FAVE DTV++ +  + N+NH+G++VN+  S+ S PA+YF +   K   I + SG  IQ W+DY    N L+V ++ L +EKP   +LS  +NLS I  +  +FVGF+A+TG   S HY+LGWSF+ + E +Q L  S LP +PRP+  H  +   +  A   ++ ++++ V    Y  RK K +++ E  E + G HRFSY+ L  AT GF     LG GGFG VY+G L   N  VAVKR+SH+ +QG+++F++E+ S+  L+HRNLV LLG+CR +G+LL+V +YMPNGSLD++LFD+   VL W +RF I+KG+AS L YLH E EQ V+HRDIKA NV+LD+ELNGRL DFG+A+ ++HG N  TT  VGT+GY+APEL   G  TI TDV+AFG  LLEVACGR+P+E     E+  L+ WV E W+  + L+  DP+L  +F   E  +V+KLGL+C+N  P++RP M QVV YL G + LP+  P
Sbjct:    1 MSKGLFLIWLISSFHLISFSTSSKDTSFVFNGF-GQSN-LALDGSATLLPNGLLQLAKDSQHQMGHAFIKKPIDF---SSSKPLSFSTHFVCALVPKPGFEGGHGITFVISPTVDFTRAQPTRYMGIFNASTNGSPSSHLFAVELDTVRNPDFRETNNNHIGIDVNNPISVESAPASYFSKTAQKNVSINLSSGKPIQVWVDYHG--NVLNVSVAPLEAEKPSLPLLSRSMNLSEIFSRRRLFVGFAAATGTSISYHYLLGWSFSTNRELSQLLDFSKLPQVPRPRAEHKKVQFALIIALPVILAIVVMAVLAGVYYHRKKKYAEVSEPWEKKYGTHRFSYKSLYIATKGFHKDRFLGRGGFGEVYRGDLP-LNKTVAVKRVSHDGEQGMKQFVAEVVSMKSLKHRNLVPLLGYCRRKGELLLVSEYMPNGSLDQHLFDDQSPVLSWSQRFVILKGIASALFYLHTEAEQVVLHRDIKASNVMLDAELNGRLGDFGMARFHDHGGNAATTAAVGTVGYMAPELITMGASTI-TDVYAFGVFLLEVACGRKPVEFGVQVEKRFLIKWVCECWKKDSLLDAKDPRLGEEFVPEEVELVMKLGLLCTNIVPESRPAMGQVVLYLSGNLPLPDFSP 623          

Query:   33 VFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRP----KQNHTVLILCVTFAVVVVIM-LIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDE-PKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKKG------HGSGGINTIRFEDFVHS 663
            V S +  F F GF  +   ++L GVA+IA +G + LT  T RV GHAFYS P++FK    ++  SFS++F IA VPE+  LGGHGLAF ++P+  L GS PSQYLGLLN+S   N ++H FAVEFDTV+DLE  DINDNHVG+++NSM+S  STPA YFL N TK+EL +  G  IQAWIDYDS K RLDVKLS  SEKP+ S+LS DV+LSS+L D M+VGFSASTGLLASSHY+LGW+FNMSGEA SLSL SLP +P      K+    LIL V+    ++I  ++V  S ++VRK+K  D +E  EL+ GPHRFSY+ELKKAT GF DKELLG GGFG+VYKG L G++  VAVKRISHES+QG+REFMSE++SIG LRHRNLV+LLGWCR R DLL+VYD+MPNGSLD YLFDE P+ +L W +RFKIIKGVASGLLYLHE WEQTVIHRDIKA NVLLDSE+NGR+ DFGLAKLYEHG++P  TRVVGT GYLAPELTK+GK T +TDV+AFGAVLLEVACGRRPIE  ALPEEL++VDWVW RWQSG   +VVD +LNG+FDE E ++VIKLGL+CSN++P+ RPTMRQVV YLE +   PEVVP+P   D+          GS G     FEDFV S
Sbjct:   19 VSSLIQDFSFIGFKKASPNLTLNGVAEIAPTGAIRLTTETQRVIGHAFYSLPIRFKPIGVNRALSFSTSFAIAMVPEFVTLGGHGLAFAITPTPDLRGSLPSQYLGLLNSSRV-NFSSHFFAVEFDTVRDLEFEDINDNHVGIDINSMESSISTPAGYFLANSTKKELFLDGGRVIQAWIDYDSNKKRLDVKLSPFSEKPKLSLLSYDVDLSSVLGDEMYVGFSASTGLLASSHYILGWNFNMSGEAFSLSLPSLPRIPSSIKKRKKKRQSLILGVSLLCSLLIFAVLVAASLFVVRKVKDEDRVEEWELDFGPHRFSYRELKKATNGFGDKELLGSGGFGKVYKGKLPGSDEFVAVKRISHESRQGVREFMSEVSSIGHLRHRNLVQLLGWCRRRDDLLLVYDFMPNGSLDMYLFDENPEVILTWKQRFKIIKGVASGLLYLHEGWEQTVIHRDIKAANVLLDSEMNGRVGDFGLAKLYEHGSDPGATRVVGTFGYLAPELTKSGKLTTSTDVYAFGAVLLEVACGRRPIETSALPEELVMVDWVWSRWQSGDIRDVVDRRLNGEFDEEEVVMVIKLGLLCSNNSPEVRPTMRQVVMYLEKQFPSPEVVPAPDFLDANDSMCLDERSGSAG----EFEDFVDS 657          

Query:   35 SQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLL-SEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPR--PKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKK-SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIE-PKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAI-VVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP 636
            SQ   F +NGFH     +SL G+A +  +GLL LTNT+ + +GHAF +  ++FK+S N  VSSFS+ FV A   + P L GHG+AFV++P+  L  + PSQY+GL N S NGN  NHIFAVEFDT++  E GD NDNHVG+++N ++S   + A Y  ++   + L + S  +IQ WIDYD+  +R+DV ++   S+KPR  ++S   +LSSIL + M+VGFS++TG + S H+++GWSF ++GEA  LSLS LP LPR  P++      + +    + +I  I+F++FY+VR+ KK  + ++  E E G +RF ++EL  AT GF++K+LLG GGFGRVY+G L  T  +VAVKR+SH+SKQG++EF++EI SIGR+ HRNLV LLG+CR RG+LL+VYDYMPNGSLDKYL++ P+  L W +R  IIKGVASGL YLHEEWEQ VIHRD+KA NVLLD++ NGRL DFGLA+LY+HG++P TT VVGTLGYLAPE ++TG+ T  TDV+AFGA LLEV  GRRPIE   A  +  +LV+WV+  W  G  +E  DPKL     +LE + +V+KLGL+CS+  P ARP+MRQV++YL G++ALPE+ P
Sbjct:   22 SQNLNFTYNGFHPPLTDISLQGLATVTPNGLLKLTNTSVQKTGHAFCTERIRFKDSQNGNVSSFSTTFVFAIHSQIPTLSGHGIAFVVAPTLGLPFALPSQYIGLFNISNNGNDTNHIFAVEFDTIQSSEFGDPNDNHVGIDLNGLRSANYSTAGYRDDHDKFQNLSLISRKRIQVWIDYDNRSHRIDVTVAPFDSDKPRKPLVSYVRDLSSILLEDMYVGFSSATGSVLSEHFLVGWSFRLNGEAPMLSLSKLPKLPRFEPRRISEFYKIGMPLISLSLIFSIIFLAFYIVRRKKKYEEELDDWETEFGKNRFRFKELYHATKGFKEKDLLGSGGFGRVYRGILPTTKLEVAVKRVSHDSKQGMKEFVAEIVSIGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYNNPETTLDWKQRSTIIKGVASGLFYLHEEWEQVVIHRDVKASNVLLDADFNGRLGDFGLARLYDHGSDPQTTHVVGTLGYLAPEHSRTGRATTTTDVYAFGAFLLEVVSGRRPIEFHSASDDTFLLVEWVFSLWLRGNIMEAKDPKLGSSGYDLEEVEMVLKLGLLCSHSDPRARPSMRQVLQYLRGDMALPELTP 630          

Query:   35 SQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLS-GSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSE-KPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPR--PKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKK-SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIE-PKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP 636
            SQ   F +N        +S+ G+  +  +GLL LTNTT + +GHAFY+ P++FK+S N  VSSFS++FV A   +   L GHG+AFV++P+  L  G+PSQY+GL N + NGN  NH+FAVE DT+   E  D NDNHVG+++NS+KS+ S+PA Y+ E    + L + S   +Q W+DYD   N++DV ++  +E KP   +++   +LSS+L   M+VGFS++TG + S HY+LGWSF ++ +A  L+LS LP LPR  PK+      + +    + +I   +F+  Y+VR+ +K ++ +E  E E G +RF +++L  AT GF++K LLG GGFG VYKG + GT  ++AVKR+SHES+QG++EF++EI SIGR+ HRNLV LLG+CR RG+LL+VYDYMPNGSLDKYL++ P+  L W +R K+I GVASGL YLHEEWEQ VIHRD+KA NVLLD ELNGRL DFGLA+LY+HG++P TT VVGTLGYLAPE T+TG+ T+ATDVFAFGA LLEVACGRRPIE  +   E  +LVDWV+  W  G  L   DP +  + DE E  +V+KLGL+CS+  P ARP+MRQV+ YL G+  LPE+ P
Sbjct:   22 SQSLNFAYNNGFNPPTDLSIQGITTVTPNGLLKLTNTTVQKTGHAFYTKPIRFKDSPNGTVSSFSTSFVFAIHSQIAILSGHGIAFVVAPNASLPYGNPSQYIGLFNLANNGNETNHVFAVELDTILSTEFNDTNDNHVGIDINSLKSVQSSPAGYWDEKGQFKNLTLISRKPMQVWVDYDGRTNKIDVTMAPFNEDKPTRPLVTAVRDLSSVLLQDMYVGFSSATGSVLSEHYILGWSFGLNEKAPPLALSRLPKLPRFEPKRISEFYKIGMPLISLFLIFSFIFLVCYIVRRRRKFAEELEEWEKEFGKNRFRFKDLYYATKGFKEKGLLGTGGFGSVYKGVMPGTKLEIAVKRVSHESRQGMKEFVAEIVSIGRMSHRNLVPLLGYCRRRGELLLVYDYMPNGSLDKYLYNTPEVTLNWKQRIKVILGVASGLFYLHEEWEQVVIHRDVKASNVLLDGELNGRLGDFGLARLYDHGSDPQTTHVVGTLGYLAPEHTRTGRATMATDVFAFGAFLLEVACGRRPIEFQQETDETFLLVDWVFGLWNKGDILAAKDPNMGSECDEKEVEMVLKLGLLCSHSDPRARPSMRQVLHYLRGDAKLPELSP 629          

Query:   19 LIFFWVFLVFSSGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLS-GSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSE-KPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLP-------RPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALP-EELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP 636
            L FFW  L  SS     Q+  F +NGF      +S+ G+A I  +GLL LTNTT + +GHAFY+ P++FK+S N  VSSFS+ FV A   + P    HG+AFV++P+ +L  GSP QYLGL N + NGN  NH+FAVE DT+ ++E  D N+NHVG+++NS+ S+ S+PA Y+ EN     L + S  ++Q W+D+D   + +DV ++   E KPR  ++SI  +LSS+L   MFVGFS++TG + S  +VLGWSF ++GEAQ L+LS LP LP       R  + +   +  ++  ++  +++I  + F + R+ K ++ +E  E E G +R  +++L  AT GF+DK +LG GGFG VYKG +  T  ++AVKR+S+ES+QGL+EF++EI SIG++ HRNLV L+G+CR R +LL+VYDYMPNGSLDKYL++ P+  L W +RFK+I GVAS L YLHEEWEQ VIHRD+KA NVLLD+ELNGRL DFGLA+L +HG++P TTRVVGT GYLAP+  +TG+ T  TDVFAFG +LLEVACGRRPIE      E ++LVDWV+  W     L+  DP L  ++D+ E  +V+KLGL+CS+  P ARPTMRQV++YL G+  LP++ P
Sbjct:   12 LSFFWQSLKSSS-----QIIDFTYNGFRPPPTDISILGIATITPNGLLKLTNTTMQSTGHAFYTKPIRFKDSPNGTVSSFSTTFVFAIHSQIPI--AHGMAFVIAPNPRLPFGSPLQYLGLFNVTNNGNVRNHVFAVELDTIMNIEFNDTNNNHVGIDINSLNSVKSSPAGYWDENDQFHNLTLISSKRMQVWVDFDGPTHLIDVTMAPFGEVKPRKPLVSIVRDLSSVLLQDMFVGFSSATGNIVSEIFVLGWSFGVNGEAQPLALSKLPRLPVWDLKPTRVYRFYKNWVPLISLLLIPFLLIIFLVRFIMKRRRKFAEEVEDWETEFGKNRLRFKDLYYATKGFKDKNILGSGGFGSVYKGIMPKTKKEIAVKRVSNESRQGLKEFVAEIVSIGQMSHRNLVPLVGYCRRRDELLLVYDYMPNGSLDKYLYNSPEVTLDWKQRFKVINGVASALFYLHEEWEQVVIHRDVKASNVLLDAELNGRLGDFGLAQLCDHGSDPQTTRVVGTWGYLAPDHIRTGRATTTTDVFAFGVLLLEVACGRRPIEINNQSGERVVLVDWVFRFWMEANILDAKDPNLGSEYDQKEVEMVLKLGLLCSHSDPLARPTMRQVLQYLRGDAMLPDLSP 632          

Query:   35 SQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLSE-KPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGE-AQSLSLSSLPSLPR--PK------QNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEE-LILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP 636
            SQ   F +N FH     +S+ G+A +  +G+L LT+ T   +GHAFY+ P++FK+S N  VSSFS+ FVI      P + GHG+AF ++P+  LS +  SQYLGL +++ NGN  NHI AVEFDT+ + E  D NDNHVG+N+NS+ S+ S+   Y+ E      L + S  ++Q W+DYD   N++DV ++   E KPR +++S+  +LSS+    M++GFSA+TG + S H+V GWSF + G+ A  L+LS +P  PR  P       +N   L   +   V+ V+ LI  + F + R+ K ++  E  E E G +R  +++L  AT GF+DK+LLG GGFGRVY+G +  T  ++AVKR+S+ES+QGL+EF++EI SIGR+ HRNLV LLG+CR R +LL+VYDYMPNGSLDKYL+D P+  L W +RF +I GVASGL YLHEEWEQ VIHRDIKA NVLLD+E NGRL DFGLA+L +HG++P TTRVVGT GYLAP+  +TG+ T ATDVFAFG +LLEVACGRRPIE +   +E ++LVD V+  W  G  L+  DP L   +D+ E   V+KLGL+CS+  P  RPTMRQV++YL G+  LP++ P
Sbjct:   24 SQSLNFTYNSFHRPPTNISIQGIATVTSNGILKLTDKTVISTGHAFYTEPIRFKDSPNDTVSSFSTTFVIGIYSGIPTISGHGMAFFIAPNPVLSSAMASQYLGLFSSTNNGNDTNHILAVEFDTIMNPEFDDTNDNHVGININSLTSVKSSLVGYWDEINQFNNLTLISRKRMQVWVDYDDRTNQIDVTMAPFGEVKPRKALVSVVRDLSSVFLQDMYLGFSAATGYVLSEHFVFGWSFMVKGKTAPPLTLSKVPKFPRVGPTSLQRFYKNRMPLFSLLLIPVLFVVSLIFLVRFIVRRRRKFAEEFEDWETEFGKNRLRFKDLYYATKGFKDKDLLGSGGFGRVYRGVMPTTKKEIAVKRVSNESRQGLKEFVAEIVSIGRMSHRNLVPLLGYCRRRDELLLVYDYMPNGSLDKYLYDCPEVTLDWKQRFNVIIGVASGLFYLHEEWEQVVIHRDIKASNVLLDAEYNGRLGDFGLARLCDHGSDPQTTRVVGTWGYLAPDHVRTGRATTATDVFAFGVLLLEVACGRRPIEIEIESDESVLLVDSVFGFWIEGNILDATDPNLGSVYDQREVETVLKLGLLCSHSDPQVRPTMRQVLQYLRGDATLPDLSP 637          

Query:   35 SQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLS-GSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENR-TKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQNHTVL-ILCVTFAVV-VVIMLIVFISFYLVRKLKK-SDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKA-LPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIV--VIKLGLMCSNDAPDARPTMRQVVRYLEGEVALP 632
            S+  +F FNG+         +G+A     GL+ LTN++    GH FY+SP++FKNS N  VSSFS+ FV A V     L GHGLAFV+SP+K L   S SQYLGL N + NG+ +NHI AVEFDT ++ E  D+++NHVG+++NS+ S  ++ A Y+ ++  T + + + +   IQAWI+YDS++ +L+V +  +   KP+  +LS+  +LS  L D M+VGF+++TG L SSHY+LGW+F ++G A ++ +S LP LPR  ++ +V  IL ++ ++  + I++ + IS+ L  K KK  +++E  E++ GPHRF+Y++L  AT GFR+ ELLG GGFG+VYKGTL  +N  +AVK++SH+S+QG+REF++EIA+IGRLRH NLVRLLG+CR +G+L +VYD MP GSLDK+L+ +P++ L W +RFKIIK VASGL YLH +W Q +IHRDIK  NVLLD  +NG+L DFGLAKL EHG +P T+ V GT GY++PEL++TGK + ++DVFAFG ++LE+ CGRRP+ P+A  P E++L DWV + W+    L+VVD ++  D   LE  V  V+KLGL CS+     RP+M  V+++L+G   LP
Sbjct:   23 SEEGEFGFNGYLYDN-----SGIAITNSKGLMKLTNSSEFSYGHVFYNSPVRFKNSPNGTVSSFSTTFVFAIVSNVNALDGHGLAFVISPTKGLPYSSSSQYLGLFNLTNNGDPSNHIVAVEFDTFQNQEFDDMDNNHVGIDINSLSSEKASTAGYYEDDDGTFKNIRLINQKPIQAWIEYDSSRRQLNVTIHPIHLPKPKIPLLSLTKDLSPYLFDSMYVGFTSATGRLRSSHYILGWTFKLNGTASNIDISRLPKLPRDSRSTSVKKILAISLSLTSLAILVFLTISYMLFLKRKKLMEVLEDWEVQFGPHRFAYKDLYIATKGFRNSELLGKGGFGKVYKGTLSTSNMDIAVKKVSHDSRQGMREFVAEIATIGRLRHPNLVRLLGYCRRKGELYLVYDCMPKGSLDKFLYHQPEQSLDWSQRFKIIKDVASGLCYLHHQWVQVIIHRDIKPANVLLDDSMNGKLGDFGLAKLCEHGFDPQTSNVAGTFGYISPELSRTGKASTSSDVFAFGILMLEITCGRRPVLPRASSPSEMVLTDWVLDCWEDD-ILQVVDERVKQDDKYLEEQVALVLKLGLFCSHPVAAVRPSMSSVIQFLDGVAQLP 623          

Query:   45 FHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELIIKSGAKIQAWIDYDSAKNRLDVKL-SLLSEKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEAQSLSLSSLPSLPRPKQN-----HTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPE 633
            F+ SGN M  +G A I ++GL+ LTN+T + +G  FY+  L+FKNS N  VSSFS+ FV +        GG+G+AFV+ P++ LS + P+ YLGL N S  G+  NHI AVE DT  D +  D + NHVG+++N++ S     A Y+++N T   L++ SG  +Q WI+YDS + +++V L  L   KP+  +LS++ +LS  L + M+VGF+++TG L +SHY+LGW+F M+G    +  S LP +PR  Q      + +L + +T + V++++++    +  +++ K  +++E  E++ GPHRF++++L  AT GF+D E+LG GGFG+VYKGTL  +N ++AVK +SH+S+QG+REF++EIA+IGRLRH NLVRL G+CR +G+L +VYD M  GSLDK+L+ +    L W +RFKIIK VASGL YLH++W Q +IHRDIK  N+LLD+ +N +L DFGLAKL +HGT+P T+ V GTLGY++PEL++TGK +  +DVFAFG V+LE+ACGR+PI P+A   E++L DWV E W++   ++V+D K+  ++ E +A +V+KLGL CS+     RP M  V++ L+    LP 
Sbjct:   28 FNTSGN-MYTSGSAYINNNGLIRLTNSTPQTTGQVFYNDQLRFKNSVNGTVSSFSTTFVFSIEFHNGIYGGYGIAFVICPTRDLSPTFPTTYLGLFNRSNMGDPKNHIVAVELDTKVDQQFEDKDANHVGIDINTLVSDTVALAGYYMDNGTFRSLLLNSGQPMQIWIEYDSKQKQINVTLHPLYVPKPKIPLLSLEKDLSPYLLELMYVGFTSTTGDLTASHYILGWTFKMNGTTPDIDPSRLPKIPRYNQPWIQSPNGILTISLTVSGVIILIILSLSLWLFLKRKKLLEVLEDWEVQFGPHRFAFKDLHIATKGFKDTEVLGKGGFGKVYKGTLPVSNVEIAVKMVSHDSRQGMREFIAEIATIGRLRHPNLVRLQGYCRHKGELYLVYDCMAKGSLDKFLYHQQTGNLDWSQRFKIIKDVASGLYYLHQQWVQVIIHRDIKPANILLDANMNAKLGDFGLAKLCDHGTDPQTSHVAGTLGYISPELSRTGKASTRSDVFAFGIVMLEIACGRKPILPRASQREMVLTDWVLECWENEDIMQVLDHKIGQEYVEEQAALVLKLGLFCSHPVAAIRPNMSSVIQLLDSVAQLPH 622          

Query:   15 IAKELIFFWVFLVFS--SGHVFSQLDQFIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLS-GSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENRTKEELI-IKSGAKIQAWIDYDSAKNRLDVKLSLL-SEKPRSSILSIDVNLSSIL-QDFMFVGFSASTGLLASSHYVLGWSFNMSGE-AQSLSLSSLPSLPRPKQNHTVLILCVTFA---VVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP 636
            ++K L   W+   F   S    S+   F+FNGF G  N ++L G A +  +GLL L   +    GHAF   P+ F    +SK  SFS+ FV A VP+    GGHG+ FV+SP+   +   P++Y+G+ NAS NG+ ++H+FAVE DTV++ +  + N+NH+G++VN+  S+ S PA+YF +   K   I + SG  IQ W+DY    N L+V ++ L +EKP   +LS  +NLS I  +  +FVGF+A+TG   S HY+LGWSF+ + E +Q L  S LP +PRP+  H  +   +  A   ++ ++++ V    Y  RK K +++ E  E + G HRFSY+ L  AT GF     LG GGFG VY+G L   N  VAVKR+SH+ +QG+++F++E+ S+  L+HRNLV LLG+CR +G+LL+V +YMPNGSLD++LFD+   VL W +RF I+KG+AS L YLH E EQ V+HRDIKA NV+LD+ELNGRL DFG+A+ ++HG N  TT  VGT+GY+APEL   G  TI TDV+AFG  LLEVACGR+P+E     E+  L+ WV E W+  + L+  DP+L  +F   E  +V+KLGL+C+N  P++RP M QVV YL G + LP+  P
Sbjct:    1 MSKGLFLIWLISSFHLISFSTSSKDTSFVFNGF-GQSN-LALDGSATLLPNGLLQLAKDSQHQMGHAFIKKPIDF---SSSKPLSFSTHFVCALVPKPGFEGGHGITFVISPTVDFTRAQPTRYMGIFNASTNGSPSSHLFAVELDTVRNPDFRETNNNHIGIDVNNPISVESAPASYFSKTAQKNVSINLSSGKPIQVWVDYHG--NVLNVSVAPLEAEKPSLPLLSRSMNLSEIFSRRRLFVGFAAATGTSISYHYLLGWSFSTNRELSQLLDFSKLPQVPRPRAEHKKVQFALIIALPVILAIVVMAVLAGVYYHRKKKYAEVSEPWEKKYGTHRFSYKSLYIATKGFHKDRFLGRGGFGEVYRGDLP-LNKTVAVKRVSHDGEQGMKQFVAEVVSMKSLKHRNLVPLLGYCRRKGELLLVSEYMPNGSLDQHLFDDQSPVLSWSQRFVILKGIASALFYLHTEAEQVVLHRDIKASNVMLDAELNGRLGDFGMARFHDHGGNAATTAAVGTVGYMAPELITMGASTI-TDVYAFGVFLLEVACGRKPVEFGVQVEKRFLIKWVCECWKKDSLLDAKDPRLGEEFVPEEVELVMKLGLLCTNIVPESRPAMGQVVLYLSGNLPLPDFSP 623          

Query:   32 HVFSQLDQ-FIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKFKNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPSKQLSGS-PSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDINDNHVGVNVNSMKSIASTPAAYFLENR-TKEELIIKSGAKIQAWIDYDSAKNRLDVKLSLLS-EKPRSSILSIDVNLSSILQDFMFVGFSASTGLLASSHYVLGWSFNMSGEA-QSLSLSSLPSLPRPKQNHTVLILCVTFAVVVVIMLIVFISFYLVRKLKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKRVLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDF-DELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVP-SPG 639
            H+ SQ +  F FNGF      + + GVA I   GLL LT+T+ +  GHAF+  PL F   ++S+  SFS+ FV A V +    GG+G+AF LSPS  L+ +  +QYLGL N + N + ++HIFA+E DTV+  E  DI++NHVG++VNS+ S+ S PA+YF + +   + + + SG  IQ W+D+D     L+V L+ L   KP  S++S  +NLS ++QD MFVGFSA+TG LA++HY+LGWSF+ S  + QSL +S LP +P PK   T L+L +   V+ +I+L++ +  YL R+ K +++ E  E E GPHR+SY+ L KAT GF     LG GGFG VYKGTL      +AVKR SH  ++G+++F++EIAS+G L HRNLV L G+CR +G+ L+V  YMPNGSLD++LF   +  L W +R  I+KG+AS L YLH E  Q V+HRDIKA NV+LD++  G+L DFG+A+ ++HG NPTTT  VGT+GY+ PELT  G  T  TDV+AFGA++LEV CGRRP+EP    E+ +LV WV + W+    +   DPKL+G+   ++E  +V+KLGL+C+N  P++RP M +VV+YL+ +V+LP+  P SPG
Sbjct:   19 HLSSQQETGFSFNGFRQ--GDLHVDGVAQILPGGLLRLTDTSEQKKGHAFFRQPLVF---NSSEPLSFSTHFVCAMVRKPGVTGGNGIAFFLSPSMDLTNADATQYLGLFNTTTNRSPSSHIFAIELDTVQSAEFDDIDNNHVGIDVNSLTSVESAPASYFSDKKGLNKSISLLSGDSIQVWVDFDGTV--LNVSLAPLGIRKPSQSLISRSMNLSEVIQDRMFVGFSAATGQLANNHYILGWSFSRSKASLQSLDISKLPQVPHPKMK-TSLLLILLLIVLGIILLVLLVGAYLYRRNKYAEVREEWEKEYGPHRYSYKSLYKATKGFHKDGFLGKGGFGEVYKGTL--PQEDIAVKRFSHHGERGMKQFVAEIASMGCLDHRNLVPLFGYCRRKGEFLLVSKYMPNGSLDQFLFHNREPSLTWSKRLGILKGIASALKYLHTEATQVVLHRDIKASNVMLDTDFTGKLGDFGMARFHDHGANPTTTGAVGTVGYMGPELTSMGAST-KTDVYAFGALILEVTCGRRPVEPNLPIEKQLLVKWVCDCWKRKDLISARDPKLSGELIPQIE--MVLKLGLLCTNLVPESRPDMVKVVQYLDRQVSLPDFSPDSPG 620          

Query:   40 FIFNGFHGSGNKMSLTGVADIADSGLLCLTNTTSRVSGHAFYSSPLKF--KNSDNSKVSSFSSAFVIATVPEYPKLGGHGLAFVLSPS-KQLSGSPSQYLGLLNASENGNSANHIFAVEFDTVKDLELGDIN-DNHVGVNVNSMKSIASTPAAYFLENRT-KEELIIKSGAKIQAWIDYDSAKNRLDVKL--SLLSEKPRSSILSIDV-NLSSILQDFMFVGFSASTGL--LASSHYVLGWSFNMSGE---AQSLSLSSLPSLPRPKQ-----NHTVLILCVTFAVVVVIMLIVFISFYLVRK-LKKSDIIEASELEIGPHRFSYQELKKATMGFRDKELLGFGGFGRVYKGTLQGTNTQVAVKRISHESKQGLREFMSEIASIGRLRHRNLVRLLGWCRCRGDLLIVYDYMPNGSLDKYLFDEPKR---VLGWDERFKIIKGVASGLLYLHEEWEQTVIHRDIKAGNVLLDSELNGRLSDFGLAKLYEHGTNPTTTRVVGTLGYLAPELTKTGKPTIATDVFAFGAVLLEVACGRRPIEPKALPEELILVDWVWERWQSGAALEVVDPKLNGDFDELEAIVVIKLGLMCSNDAPDARPTMRQVVRYLEGEVALPEVVPSPGGYDSKK 645
            FIF+GF G+ +++ + G + I  +GLL LT+  S V G AFY  P++    NS N+ V SFS++F+          GG G  F LSP+  +    P QY+GLLN   +GNS+NH+FAVEFDTV+  + G     NH+G+N NS+ S    P AYF  N + KEE  + SG  IQ ++DY      L++ +  + L  KPR  ++S +V  LS I+ D MFVGF+A+TG    +S+HYV+GWSF   GE   A  L +S LP  P  K      N  V+ L V  + V+ IML++   F + +K +++ +I+E  E++  PHRF Y++L KAT GF++  ++G GGFG VY+G ++ ++ Q+AVK+I+  S QG+REF++EI S+GRLRH+NLV L GWC+ R DLL++YDY+PNGSLD  L+ +P+R   VL W+ RF+I KG+ASGLLYLHEEWEQ VIHRD+K  NVL+DS++N RL DFGLA+LYE G+   TT VVGT+GY+APEL + G  + A+DVFAFG +LLE+  GR+P +         + DWV E   SG  L  +DP+L   +DE EA + + +GL+C +  P++RP MR V+RYL  +  +PE+  + G  DS +
Sbjct:   30 FIFHGFKGNQSEIHMQGDSTITSNGLLRLTDRNSDVVGTAFYHKPVRLLDSNSTNTTVRSFSTSFIFIIPSSSTSNGGFGFTFTLSPTPNRTDADPEQYMGLLNERNDGNSSNHVFAVEFDTVQGFKDGTNRIGNHIGLNFNSLSSDVQEPVAYFNNNDSQKEEFQLVSGEPIQVFLDYHGPTKTLNLTVYPTRLGYKPRIPLISREVPKLSDIVVDEMFVGFTAATGRHGQSSAHYVMGWSFASGGEHPLAAMLDISQLPPPPPNKAKKRGYNGKVIALIVALSTVISIMLVLLFLFMMYKKRMQQEEILEDWEID-HPHRFRYRDLYKATEGFKENRVVGTGGFGIVYRGNIRSSSDQIAVKKITPNSMQGVREFVAEIESLGRLRHKNLVNLQGWCKHRNDLLLIYDYIPNGSLDSLLYSKPRRSGAVLSWNARFQIAKGIASGLLYLHEEWEQIVIHRDVKPSNVLIDSDMNPRLGDFGLARLYERGSQSCTTVVVGTIGYMAPELARNGNSSSASDVFAFGVLLLEIVSGRKPTDSGT----FFIADWVMELQASGEILSAIDPRLGSGYDEGEARLALAVGLLCCHHKPESRPLMRMVLRYLNRDEDVPEIHDNWGYSDSSR 652