Cotton_D_gene_10024810, Cotton_D_gene_10024810 (mRNA) Gossypium raimondii

Query:   41 TPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHV-----------DGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYC-NFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
             P  ++ P IQ+V P +L      +  +EPR VA+GPFHH NP+ + AE+ KL     F+  +    + L  KV+ +I +LR+CY  E  + YD++ LAW+LF+DGC+ L  +   ++ + +EL+ K              ENQ+PY++L++L+ S+   +  +++I  ++  N+    + +  K V             +K+ AHLL+ LR  +L   +   + +K   +           ++FR+++EL  +GIH K S +  L DI F   +F G L +P + VDDST  KF+NL+A EMC DF+NDF VTSY+ F+D LID ADDVKELR  G+L+N  GSD+EVA LFN++  DLVP+   Y  V  +I K+    W   ++Q  + +F +PWTFLAF+G +  L  + IQ +F++
Sbjct:   22 APDYSSNPKIQKV-PFMLRKPKTSEKYYEPRAVAIGPFHHGNPRCELAEEFKLMLTKRFLKYTSQTVEALHQKVEKKIKELRECYAEEATQTYDDETLAWMLFLDGCSTLQFIHSFVDEELEELSIKRDQIAFAQQDLFLLENQVPYQVLELLMSSSNKCEDLKKAIETYVQANIGAPGKKQSEKKVAITMEKEKEPAHQEKEPAHLLDLLRTRMLGPPKNPDKRAKDHSV-----------QSFRNVQELDAAGIHFKLSNSSLLGDISFVSHSFAGYLSLPAISVDDSTGPKFMNLIAYEMCPDFQNDFAVTSYISFLDALIDHADDVKELRSAGVLYNLLGSDKEVAKLFNEIGTDLVPNTDIYHDVKAEIEKHYKTKWKTWMSQFCHDHFRSPWTFLAFVGVLAALGLTGIQTWFAV 430          

Query:   14 SMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVS-GTNRDD-LFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFL--GKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTF 428
            S  EK+K+   AL E   +           Q   P IQRV P +L    +    +EPR+VALGP HH   K+++AE+ KL+    F+  S  TN D+ L   V+ +I +LR+CY  E  + +D++ LAW+LFVDGC+ L  +    E   +    K            X ENQLPY+L ++LI S+   +    S      H+++        +     K       RL D L T             M+        H  +FR+++EL+ +GIH +PS   +L DI+F   FL  G L +P + VDDS   KF+N++A EMC DF+NDF VTSY+ F+D+LID ADDVK LR  GI+ N  GSD+EVA LFN++S DLVP+   Y  V   I  +    W   +AQ ++ +F++PWTF
Sbjct:   60 SRGEKLKKMRXALAEAAQK-----------QNAXPKIQRV-PFMLRDHKNLDKYYEPRVVALGPRHHGKEKYKQAEKVKLQLTEHFIKDSEQTNNDETLLKNVEDKIKELRECYDXEATKDHDDEALAWMLFVDGCSTLEFMXKYXE--LEXFKIKRDQVAFVEQDMFXLENQLPYQLXELLISSSNKRRPPSLSTEPGCTHHILDLRPMVGPRPSQSTK--PGCTHRLLDLLQT-------------MVXPRPSXLXH--SFRNVQELQAAGIHFRPSEKNSLMDIYFKPLFLCCGFLYLPIIKVDDSMGPKFMNIIAYEMCPDFQNDFVVTSYIGFLDSLIDHADDVKHLRKKGIVQNLLGSDQEVAELFNEISTDLVPNXAIYRXVTAQIEXHYKTKWKTWMAQFFHDHFNSPWTF 447          

Query:  106 NRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFI-AHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNF--LGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            N + L  KV  +I+DLR+CY  +  + YD++ LAW+LFVDGC+ L    Y  E K +E   K              ENQLP++LLK LI  +K  Q    SI  FI  H         K       ++  HLL+ LR  ++        ++K GR     G S      FR+++EL+ +GIH + S T +L+ I F   F   G L +P + VDDS   KF+N++A EMC DF+NDFEVTSY+ F+D+LID  DDVK LR  GI+ N  GSDEEVA LFN+++ DLVP+   Y  V   I  +    W   +AQ ++ +F++PWTFLAFIG ++GL  S IQ ++++
Sbjct:  107 NAETLLKKVGDKINDLRECYDEKATKDYDDEALAWMLFVDGCSTL-EFMYKYE-KLEEFKIKRDQVAFAEQDMLLLENQLPHRLLKWLIKKSKIHQELNTSIEGFIRMHGGAPRDPATK-------REPTHLLDLLRTRMVGCPPS--PSTKSGRRSTEGGHS------FRNVQELQAAGIHFRYSKTNSLRAISFKLRFQCCGFLYLPIIKVDDSMRPKFMNMIAYEMCSDFQNDFEVTSYIGFLDSLIDHPDDVKHLRKKGIVRNLLGSDEEVAQLFNEIATDLVPNDAIYRNVKTQIEDHYKTKWKTWMAQFFHDHFNSPWTFLAFIGVLLGLGLSGIQTWYAV 436          

Query:   33 KQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDK--LAWVLFVDGCAVLCAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSA-KDSQIWEQSITDFI-AHNLMTNT------------------EHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHF--YCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            K Q +  S  P  ++P+IQ VS  L + K + +  FEPR++A+GP HH   KF   E+ K + AA FV+ SG + + L+ +V+  I +L++CY  +  E YD D+  LAW+ FVDGC++L  ++       +E   K              ENQ+PY++L +L+ S+ K+  +W   I  F+  H+                       E R G  ++      HLLE LR  +L         +K GR             +FR+ KEL  +GIH + S    L+DI F   C F G L +P +  D      FLNL+A EMC DF+ND+ VTSYL F+ + I   +D K+LR   ILHN   +DE +A LFN++  DLV +      +   + K+  + W   +AQ +  +FS+PW  LAFIGA+  L  SAIQ ++S+
Sbjct:   18 KNQDSSTSVVPSRSRPIIQNVSRTLRSNK-NLEKYFEPRVLAIGPIHHG--KFPEWEELKYRLAADFVNDSGRSEEFLYKEVEDNIKELKQCYDEKTTERYDGDEASLAWMFFVDGCSILQFIQ--KYSTLEEFEIKRDQVFFAEQDLFLLENQIPYEILNLLMSSSIKNEDLW-HGIQXFLDMHSTAAGASAKPFRWYKRMMRQDLKFELRLGVCMEDSWPTTHLLELLRTRMLGP-------AKNGRE----AADNELPPSFRNAKELMAAGIHFRCSEGMLLRDISFKSLC-FAGFLFLPAMNAD--AMPLFLNLIAYEMCPDFQNDYAVTSYLSFLSSFITHPEDAKQLRSARILHNKLETDEALAQLFNEIGPDLVSNPSIIH-ISSRLEKHYKSKWKAWMAQFFEDHFSSPWAMLAFIGALTALFLSAIQTWYSI 437          

Query:    8 PAEPL-----NSMEEKMKEFDSALHE-----VQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNR--DDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEG-------KFDELNTKXXXXXXXXXXXXXXENQLPY----KLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKG--KHVDGDKDYA------------HLLERLRDELLTGEEMKIENSKIGRMLLSWGDS-----RRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCR-DFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPD--QGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            P+EPL     N  ++K +E   +        ++++  Q  Q        K  I +V P  L    D  I   P++V+LGP+HH   + ++ ++ K +  +L   +  TN+  +   + +K   +  R CY+        +++   ++ +DGC VL   R   EG       + D +                 ENQLP     +LL + +G  +   +  +    F    + T+    K     ++    YA            H L+  R  LL      +    I R    W  S     +R ++    + ELKE+GI  K   T    D+ F     G L +PRLL+ D T S FLNL+A E C  D  ND  +TSY+ FMD LI+S  DV  L   GI+ ++ GSD+EVA+LFN++ +++V D        +  D+++Y ++ W    A + + YFS PW  L+FI A++ L  +  Q ++ +
Sbjct:   52 PSEPLHIVIQNGCDQKFEEGPKSPESEWXINIKDKLDQAGQDDAVSSWAKHCIYKV-PHYLREGDDKAIV--PQIVSLGPYHHGKRRLRQMDRHKWR--SLLRMLKRTNQCIELYLNSIKEVEEKARACYEGPAAMGLSSNEFVEMMVLDGCFVLELFRGVGEGFKQLGYPRNDPIFAMRGSMHSIQRDMIMLENQLPLFILDRLLGLQLGDPEQKGLVAKLALRFFDPLMPTDEPLTKSDRNKLESSLAYATTFDPLSEQGGLHCLDVFRRSLLRTGLQAVPRVWIKR----WSHSNRVADKRRQQLIHCVTELKEAGIKFKKRKTDRFWDVKFEN---GILKIPRLLIHDGTKSLFLNLIAFEQCHLDCSND--ITSYVIFMDNLINSPQDVGYLHYCGIIEHWLGSDDEVADLFNRLCQEVVFDINDSYLSPLSADVNRYYDHRWNAWRASLKHNYFSNPWAILSFIAAVVLLFLTFAQTFYGV 524          

Query:   74 ALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDN-DKLAWVLFVDGCAVLCAVR--------YGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHR-KGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPD-QGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            A  P  H        E+ K +    F+   G   +   + +   + DL+  Y P + E  D+ D+   ++ +DGC +L  +R        Y         + K              ENQLP  +L  L+    D    E  +   +       T     GK V       H L+  R   L GE       K G          RH +   S  EL E+GI  K S T +LKDI F     G L +P ++VDD+T S FLNL+A E       + EVTSY+ FMD +ID+A DV  L   GI+HN  GSD+ VA+LFN +S+D+  D +   + V K+++ YC  PW    A + +TYF  PW  ++ +  +   + + +Q  +S+
Sbjct:   46 AYKPQDHKRNNLNPMEEHKRRALVHFLKRCGKPVELFVNALAEVVQDLKDSYNPLEPEWRDDTDRFLQLMILDGCFMLEVLRVASHLLDDYAPNDPVFSNHGKLHTMPYIKRDMLMLENQLPILVLDKLVAVESDYAKDEGFVIKLLIKFFSPGTAASITGKCV-------HALDVYRKSQLLGEPY----CKTGHCRPE--TVNRHEEIIWSATELNEAGIRFKESKTTSLKDISFS---RGILRLPSIIVDDTTESMFLNLIAFERFHVGAGN-EVTSYIFFMDNIIDNARDVALLHSKGIIHNALGSDKAVADLFNSLSKDITLDPESSLDAVHKNVYHYCKKPWNVWRANLMHTYFRNPWAIISLVAGVFLFVLTIVQTGYSI 415          

Query:   17 EKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLL--LNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVL-CAVRYG---MEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTE---HRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVP--DQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            E   +F++   ++     Q+  G TP  +    I +V   L  +N KA     + P++V++GP HH     +  E+ K ++   F++ +G + +D   K+K + + LR CY    +E   +D+   ++ VD   ++   +RYG   +    D +  K              ENQLP+ + + L  +A+       S+ D        +T     R G          H ++ +R   L  ++ + EN      L              S+ +L ++G+  K  ++KNL D+   C   G L +P L + DST     NLVA E C    N      Y+  MD L+++ +DV+ L   GI+ N  G + EV+ L N + + ++   D+  Y  ++KD++KY   PW    A + + YF+TPW  ++ I A   ++ + IQ   S+
Sbjct:    6 EATHDFENPRIQLTTSMSQELDGLTP-LSASCCIYKVPEQLRCVNEKA-----YTPQVVSIGPIHHGKKGLEDMEEHKKRYLQYFLYRTGVSLEDYVTKIKGKEEKLRSCYA-HTIELC-SDEFVRIILVDAAFIIELLLRYGGYIVHDSNDRIFNKPWLINIICPDMLLLENQLPFFIXEDLFATAEVPAT-VPSVFDLSYTYCKVSTSLYVKRDGLGSSSSFKVEHFVDLVRTLNLPTDQEENENRGSVESL-----------AVPSMTKLHQAGVKFKARSSKNLFDM---CFQEGILEIPNLNISDSTELVLRNLVAFEQCHCTPNTRYFNDYIFLMDYLVNTPNDVELLVKNGIVENMLGDNNEVSTLINSLGKGVLVFRDEFYYATLMKDLNKYYEKPWNKWKADLKHKYFNTPWKIISVIAATFIIILTLIQTVSSI 426          

Query:   68 FEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVL-CAVRY---GMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGD-----KDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            + P++V++GP HH     +  E+ K ++   F+  +  +  D    +K Q   LR CY  E +E   +D+   ++ +D   V+   +RY      G+ D+  TK              ENQLP+ +L++L  +   S   + S+ +    +L    + ++ + + G+     ++  H ++ +R               + R L S            ++ EL ++G+  K     +L DI+F C   G L +P+L V D+T  K  NL+A E+CR  + ++ +T+Y+  M  L  +  DV+ L   GI+ N+ G  ++++ L       +V +   Y  + KD++ YC +     +  +   YF+TPW  ++ + A+I L+ ++IQ   S+
Sbjct:   71 YTPQVVSIGPLHHGEEHLKGMEEHKKRYLLDFLSRTRVSFYDCIKMIKIQEGKLRGCYA-EPIEL-GSDEFVRIVLLDAAFVIEFLLRYYSVNFLGQADDTVTKPMMMWDVRPDFLLLENQLPFFILQVLFNTLFSSADQQPSLLEISYFSLQREIDSKRKEEIFGEICSSGEEVQHFVDLIR--------------ILYRPLKSKTGGELKGTAVPNVTELVQAGVEFKVGKGSSLFDINFSC---GTLKIPKLTVCDTTDLKLKNLLAFELCRHRETNY-LTNYVFLMKRLAKTPKDVELLVEYGIIDNWLGDAKKISTLLLDFDTGVVGNDYYYASLCKDLNDYCRSRRHKWMTNLRRNYFNTPWRIISIVAAVILLILTSIQTVCSI 441          

Query:   68 FEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVL-CAVRYGMEGKF-----DELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNL--MTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVP--DQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLPQ 451
            + P++V++GP HH     +  E+ K ++   F+  +G +      K+K +  +LR CY         +D+   ++ VD   ++   +RY  EG       D +  K              ENQLP  +L+ L  +A +      S+ D         TN    KG          H ++ +R   L   E  ++N +    L              S+ +L+++G+  K  + KNL DI   C   G L +P+L + D+T     NL+A E C   +N F  + Y+  MD L+++ +DV+ L   GI+ +  G + EV+ L N + + L    D+  Y  ++K+++ Y   PW    A +   YF++PWT ++ I A   ++ + IQ   S  Q
Sbjct:   53 YTPQVVSIGPLHHGKEGLEDMEEHKKRYLKYFLDRTGVSLAGCVQKIKDKEAELRGCYA--HTIGLCSDEFVRIILVDAVFIIELLLRY--EGYVVRDSNDRIFNKPWLLKFIVPDMLLLENQLPLFILEDLFATA-EVPASVPSVLDLFYEFCKESTNFYMEKGNWERPSFKVEHFVDLVRTLHLPTPEENLKNGESVETL-----------AVPSMTKLRQAGVKFKARSGKNLFDI---CFKDGILEIPKLYIYDNTELVLRNLIAFEQCHCTRNTFYFSDYIILMDNLVNTPNDVELLVKNGIVEHLLGDNNEVSTLINSLGKGLFVFRDEFYYATLLKELNIYYEKPWNKWKADLKQKYFNSPWTTISVIAATFIIILTLIQTVCSFSQ 427          

Query:   68 FEPRLVALGPFHHDNPKFQRAEQSKLKFAA-LFVHV--SGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVL--------CAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQ--------IWEQSITDFIAHNLMTNTEH-RKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPD--QGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            + P +V++GP+HH  P  +  +Q K ++   L      +G    D    V  + +D+R CY   +       +L  ++ VDG  ++         + R       D +                 ENQ+P+ +L++L   +K S+        + + S+  F    L  + E   K  H+ G     HLL+ +R   +      I +   G    S           RS+K+L ++GI  K     +  DI F     G L +P++ VDD     FLN VA E C +  +   +T+Y  FM+ L  +  D   L    I+ NY GSDEEV + F  + +D   D       ++ KD++++CNN W    A    TYF TPW+F++    +I LL +AIQ   ++
Sbjct:   82 YHPHIVSIGPYHHGKPDLEMMQQHKWRYLRDLLARTPPTGPTLADYLQLVAFKEEDIRGCYS--ETRKLSKSELVQMMVVDGLFIIEIFFRVERLSERDPCVDPDDAIFNLNWLLPKLMLDLLRLENQIPFFVLEMLFNQSKPSRPNCDEYSSLSKASLKFFNFAVLQRSDEDLEKYYHLGG----VHLLDLIRKTYI----HDIPHPPRGNAFES-------VDKIRSVKKLHQAGIKFKKGEAASFLDIKFRN---GVLEVPQMTVDDLRVHLFLNFVAFEQCYNHCHK-HITTYAVFMNCLNGTPADTSFLCDRNIIENYLGSDEEVTHFFKNLGKDAAFDINASYLLQLFKDVNEHCNNVWNVQWAGFMLTYFDTPWSFMSASAVLIALLLTAIQTVLAI 464          

Query:   13 NSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVR-YGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCN-FLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            N+   + K F S +   ++ K+ Q       +T    I +V P +L    DF+I FEPR+V++GP+HH     + AE  K      F+  S    + L++K+ ++I +LR CY     + Y+++ LAW++ VDGC++L  +R Y  EGK  +L  K              ENQLP+++L++L+    +  +  Q I  FI     T+    K    D ++  AHLL+ LR  LL  +      +  G     W        +FR++ ELK +GI  KP+ + +L+DI F     LG L +PR+ +DDST S+FLNL+A EMC +  N+  VTSY+CF+D+LID  +DVKELR   +L N+ GSD+EVA LFN+++ DLVPD   Y+ V   I K+     +  +A+  +++FS+PWT LAF+GA++ L F  +Q Y+++
Sbjct:   54 NASSSREKRFKSVMGGPEDSKRSQLS-----ETKWARIPKV-PHMLRGTKDFKILFEPRVVSVGPYHHHKHDLRAAEMLKRLMTKRFILESRQAIEVLYNKIVSEISELRNCYNKNATKKYNDEDLAWMMLVDGCSLLHFIRCYTTEGKLKDLPIKYHNAAFAQQDLFLLENQLPFRVLELLLEPGFEEGM--QMIEQFIGSAAETDPPAVKS---DNEEKPAHLLDLLRRRLLGNQTASETEAGKG---TGWN-------SFRNVNELKAAGIRFKPAKSGSLRDISFNSYILLGFLKLPRITIDDSTKSRFLNLIAYEMCPEVPNEPVVTSYICFLDSLIDDPEDVKELRRQHVLRNFLGSDKEVARLFNEIATDLVPDSDAYKDVKGKIQKHYEIKASTWIAEGLHSHFSSPWTVLAFLGAVVALFFGGLQTYYTV 471          

Query:  273 TFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGK-LMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDAL----AQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            +FR++KEL  +GI +K S T++L+DI F  N +   L +P + +D+ST + FLNL+A EM  D  +DF   SYL F+D+LID ADDVKEL+  GIL N  G+ EEVA  FN +S +L  +   Y+ V   I K+  N +   L     Q   TYF +PWT +A++GA + L F+A+Q YFS+
Sbjct:   30 SFRNVKELMAAGIRIKRSPTRHLRDISFRSNGITACLRIPPITIDNSTKAMFLNLIAYEMSSDVDHDF--ISYLRFLDSLIDHADDVKELQSIGILQNNLGTHEEVAQFFNTVSANLESNFHAYKDVRVRIRKHLKNHYNSKLKMWMTQCLDTYFGSPWTIIAWVGAALALFFTAVQTYFSV 209          

Query:   59 NMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQI--DDLRKCYKPEDVEAYDNDKLAWV--LFVDGCAVLCAVRYGMEGKF-------DELNTKXXXXXXXXXXXXXXENQLPYKLLKIL---IGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSR-RHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVP--DQGRYEKVIKDIHKYCN----NPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            N++   +  F P+++++GPFH+ +P  +  E+ K+++    +      +    +++ +Q      R+CY      A+D D   +V  + +DGC VL  +R  +  +F       D + T               ENQLP+ +LK L   I  A+D  + +  +T F       N E     +++ + ++ H+LE  R   L+     I  S   ++ +S      + R+   S+ EL+++G+ +K     +L DI+F     G L +P L +DD+TA  FLN VA E C D K  F  T+YL F D+LI+S+ DV  L   GI+++  GSD++VA+LFNK+ R++V   D+    + IK ++ YC     + W      + + YFS PWTF + + AI  LL +  Q Y+++
Sbjct:   48 NLREVHKNAFVPKIISIGPFHYGDPGLRFMEEHKVRYLLRLLGSRTPEKGGQAEELMSQELEQKTRQCY----TGAFDIDSNDFVQMMVIDGCFVLELLR--LYNRFEREKNVDDPIFTIRWMLRTLQRDLLKLENQLPFFVLKKLFELISLAEDPPLIDLVLTFFDPLLPRKNIE----GNLNPEGEFDHMLEVFRSTFLSSVNQDI-TSGCEQLKISVNVPLVQERQLIHSVTELEKAGVKLKKREDCDLLDINFQA---GVLKIPPLYIDDNTAVLFLNFVAYEQCEDTKPFF--TNYLMFFDSLINSSADVGILHKNGIINHVLGSDQDVADLFNKLGREVVYDLDECYLSQQIKRVNNYCKTYYASKWRVWFTNLKHDYFSNPWTFFSLLAAIALLLLTTAQTYYTV 443          

Query:  235 HLLERLRDELL----TGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGK-LMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYE----KVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFS 448
            HLL+  R   L    +G     EN       L   D +    +FR++KEL ++GI +K S T++L+DI F  N +   L +P + +D+ST + FLNL+A EM  D  +DF   SYL F+D+LID ADDVKEL+  GIL N  G+ +EVA  FN +S +L  +   Y+    K+ K +  + N+  T  + Q   TYF +PWT +A++GA + L  + +Q YFS
Sbjct:   34 HLLDLFRRNFLGDERSGSPTHPENEN-----LEVRDVKEVMASFRNVKELMDAGIRIKRSPTRHLRDISFRSNGITACLRIPPITIDNSTKAMFLNLIAYEMSSDVDHDF--ISYLRFLDSLIDHADDVKELQSIGILQNNLGTHDEVAQFFNTVSANLESNFHAYKDVRVKIRKHLQSHYNSKLTMWMTQCLDTYFGSPWTIIAWVGAALALFLTFVQTYFS 249          

Query:   31 NQKQQQAQGSTPPQTTKPLIQRVSPLLL--------------NMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDV------------EAY------DNDKLAWVLFVDGCAVLCAVRY-----GMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKIL---IGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDS---RRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMC-RDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLV--PDQGRYEKVIKDIHKYCN----NPWTDALAQVYYTYFSTPWTF 428
            NQKQ Q Q   PP+    +   +   LL              +M+   +  F P+++++GPFH+ +P  +  E+ K+++    +        +  +    Q+  + K  + ED+            E Y      D+D+L  ++ +DGC VL  +R        E   D + T               ENQLP+ +L+ L   I    D  + +  +T F   + +   ++ KGK ++ ++++ H+L+  R   L+    + + +  G   L   D+      R+    + EL+E+G+  K     +L DI F     G L +P L +DD+T   FLNLVA E C +D K  F  T++  F D+LI+S  DV  L   GI+++  GSD++VANLFNK+ R++V   D+    + + D++ YC     + W      +   YFS+PWTF
Sbjct:   20 NQKQTQGQ---PPEWVIEMNNEIKEGLLCDSGKSWTVYRVPKSMRGIQKNAFLPKIISIGPFHNKDPGLRIMEEHKMRYLLRLLESGPRENGERVEDSAQQVPQVVKAIRLEDLAESMRMLEQKTRENYSEDLQIDSDELIQMMVIDGCFVLELLRLYFKFDNEEEVEDPIFTTRWMLRTLQRDLLKLENQLPFFVLEKLYELIRLVDDPPLVDLVVTFF---DPLLPRKNIKGK-LNPNEEFDHMLDVFRSTFLSSINERTKPA--GWKQLQKLDNIPLVEERQLIHCVTELQEAGVRFKMREDLDLLDISFKD---GMLKIPPLYIDDNTVPLFLNLVAYEQCDQDAKPFF--TNFCMFFDSLINSHTDVGILHKNGIINHVLGSDKDVANLFNKLGREIVYDLDECYLSQQMMDVNDYCKQYFASKWHVWFTNLIRDYFSSPWTF 453          

Query:   68 FEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKXX--------XXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDS-----RRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCR-DFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFST-PWTFLAFIGAIIGLLFSAIQAYFSL 449
            + P++V+LGP+HH   + +  ++ K +     +  +  + +   D +K   +  R CY  E      +++   ++ +DGC +L   R G+ G F  L                         ENQ+P   L     +  D    E S+      + +            GD+   H LE  R  LL      +    + R    W  S     +R ++    + +L+E+GI  K   T    DI F     G L +PRLL+ D T S FLNL+A E C  D  ND  +TSY+ FMD+LI+S +DV  L   GI+ ++ GS+ EVA+LFN++ +++V D       I D                  +Y S+ PWT ++F+ A++ L  +  Q ++++
Sbjct:  117 YIPQIVSLGPYHHGRRRLRNMDRHKWRSLHHILKRTNHDIEIYLDAMKELEEKARACY--EGTICLSSNEFVEMMVLDGCFILELFR-GVAGGFKHLGYARNDPVFAIRGSMHSIQRDMIMLENQIPLFPL-----TKSDRNRLESSLGYTTTFDPL------------GDQGGLHCLEVFRRSLLRTGPRPVPRIWMKR----WSHSNRVADKRRQQLIHCVTQLREAGIKFKKRKTDRFWDIKFKN---GILRIPRLLIHDGTKSLFLNLIAFEQCHLDCSND--ITSYVIFMDSLINSPEDVGYLHYCGIMEHWLGSESEVADLFNRLCQEVVFD-------IND------------------SYLSSFPWTIISFVAAVVLLALTFAQTFYAV 459          

Query:   68 FEPRLVALGPFHHDNPKFQRAEQSK-LKFAALFVHVS--GTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVR-YGMEGKF---DELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAK----DSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKT--FRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMC-RDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLV--PDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            ++P ++++GP+H   P  +  E+ K L   +L       G    D    ++    + R+CY   ++   D      +L +DGC ++   R  G    F   D L +               ENQLP+ +L+ L    K    +S     S+     +N +   +    KH +      H L+ LR   +  E+      ++G +         HR T   + + +L+++GI +K     +   + F     G + MP + +DD     F N VA E+C +D      +T+Y   +D LI+++ DV  L    I  NYFG+D  VA   N + +D+   PD     K+  D+++Y +N W   LA + YTYF TPW+F++   A I LL + +Q ++++
Sbjct:   60 YQPHIISIGPYHRGEPHLKMIEEHKWLYLGSLIARTQRHGLGLQDYLRALQPLEMEARECYS--EIIHLDTHDFLEMLVLDGCFIIDFFRKIGKMHPFEPDDPLVSMSWVFSFFLRDLLLLENQLPFFVLQRLFDLTKMPGEESGPSLASLVLGFFNNTLQRPDEILQKHCNLKG--KHFLDLLRLSFIPEEQ------ELGTL--------DHRPTHLIQCVSKLRKAGIKLKSGKADSFLTVKFRN---GVMEMPPVTIDDFLTCFFQNCVAFELCHKDCTK--HITTYATLLDCLINTSKDVGHLCERNIFENYFGTDAAVARFINNLGKDVTFDPDNCYLSKLFNDVNEYYHNGWHVQLAGMKYTYFDTPWSFISAFAAFILLLLTIVQTFYTV 434          

Query:   28 EVQNQKQQQAQGSTPP-QTTKPLIQRVSPLL--LNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWV--LFVDGCAVLCAVRYGMEGKFD--------ELNTKXXXXXXXXXXXXXXENQLPY----KLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPD-QGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            +V N+       ST   Q  K  I RV   +  LN KA     ++P+ V+ GP+HH     Q  E  K +    F   S      L + +   + DL+  Y   D  A+  D  A++  + VDGC +L  +R       D          + +              ENQLP     KLL +    AKD ++  + I  F      ++ E   GK +       H+L+  R                 + LL  G  R            K  GI +K    KN                      D+T S FLNL+A E       + EVTS++ FMD +ID+A DV  L   GI+ +  GSD+ VA LFN +S+D+  D  G    V K ++ YC   W +  A + +TYF  PW  L+ I A      +  Q  F++
Sbjct:    6 QVSNRLDNMVDTSTEAEQWKKRSIYRVPTCVTDLNKKA-----YKPQAVSFGPYHHGEEHLQTMEDHKRRALLHFFKRSDKPIKLLVESLAEVVQDLKDSYDLLD-PAWQKDTSAFLQLMIVDGCFMLEILRTATHTMDDYDPNDPIFSDHGRLYIMPYVRRDMLMLENQLPMLVLDKLLAVESDKAKDPELINKLILKFFT---TSSPEAGMGKCL-------HVLDVYR-----------------KSLLQEGPGR------------KPPGIRMK----KN----------------------DTTESMFLNLIAFERLHVGAGN-EVTSFIFFMDNIIDNAKDVILLHSRGIIQSALGSDKAVAKLFNSLSKDITLDPDGPLYGVHKKVNDYCRKSWNEWRANLIHTYFRNPWAILSLIAAAFLFALTIAQTVFTI 373          

Query:   28 EVQNQKQQQAQGSTPPQTTKPLIQRVSPLL--LNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAV-----RYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHF---YCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVP--DQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFS 448
            EV    Q   +  TP  TT   I RV   L   NM+A     + PR+V++GP HH        E+ KL++   F+  +    ++  + +  + +  R  Y  E ++    ++   ++ VD C ++  +      + +E   D +  K              ENQLP+ LL  L           ++  D+  ++ +  ++    +H     +  H ++ L   L          SK  + ++             +   L+E+G+  K  +     D      Y N  G L +P L++ +   S F NL+A E C D    + +T Y+  MD LI++  DV  L   GI+ N+ G +  V NLFN++  D     +   +  + + ++KY ++PW    A + + YFS+PW   + I A+I L+ + IQ  F+
Sbjct:    8 EVATSLQGMLEKLTPLSTT-CCIYRVPQKLRKANMEA-----YTPRVVSIGPLHHGEEHLVAMEEHKLRYLQKFLSETRKTLEECVEIIYREEEKARGYYM-ESIKM-SREEFVKMILVDACFIIEVILGFSSSHSIETG-DRIYNKPRLFIDVRRDMTLLENQLPFFLLLSLYSLRAPPGPLPENQNDYAHYSFLLLSKKISSRH-----EIKHFVDLLIVCLQPSSSSLPPESKSFKFVIP------------TATYLREAGVRFKLGSKDKDNDKLLDLDYNN--GVLKIPHLILQEKCESLFRNLIAYEECHDHAQTY-ITDYMYLMDHLINTTKDVNLLVRKGIISNHLGDNHAVKNLFNRLLIDTTTCKETFHFAGIYEKLNKYYDSPWNRWQATLRHDYFSSPWRGASTIAAVILLVLTLIQTVFT 411          

Query:  273 TFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRY-EKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            T  S+ EL +SG+   P T   +  I F    +  L +P + +D +T     NLVA E   +      +T Y   M+ +ID+ +D K LR  GI+ N   SDEEVANL+N MSR +   +  + +KVI+D++KY +  W     +    Y    W FL F+ AI+ +L   +QA+ S+
Sbjct:  235 TIPSVSELSKSGVRFLP-TNGGISSITFDAKMV-TLYLPTVSLDVNTEVTLRNLVAYE-SSNASGPLVITRYTELMNGIIDTKEDAKFLRERGIVLNRLKSDEEVANLWNGMSRSIRLTKVPFLDKVIEDVNKYHSGRWKVKAGKFMKRYVFGSWQFLTFLAAILIVLLMTLQAFCSV 409          

Query:   67 CFEPRLVALGPFHH-DNPKFQRAEQSKLK--FAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVL----CAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLG-KLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL-PQN 452
            C+ P +V++GP+HH D+P  + AE   LK      F + SG  R+DL+  V       RKCY     +   ++    ++ +DGC +L    C +    + K     +               ENQ+PYK+L  L+    D    ++ + +F+    +      K   ++ +   AHLL+   +  +     +  + K        GDS+    ++RS+ ELK  GIH+ PS T    D+ +     G  + +PR+++DD T S  LNL+A E C      F VTSY+CF+D+LID ++DVKELR  GIL N  GSD+EVA+LFN++S  +V D   Y  V   I K+C N     +A+    +FS+PWTFLAF GAI  L+ + IQ Y +L P N
Sbjct:   36 CYNPLVVSIGPYHHNDDPNHELAEMQSLKNEMVEQFANNSGKTREDLYRNVAELASSARKCYDEGSTKNVGDNAFTKMMLLDGCFILQFIFCFLHDSQKLKL----SNRVLAYFVKRDLFLLENQIPYKVLTSLMSLGFDGNKGQELMENFMDE--VRGLPRGKSGDMENNNQPAHLLDFYHNRFMGKRGQENPSRK--------GDSQW--SSYRSVMELKSVGIHLMPSKTDMYTDLRYKSTMRGGTVTLPRIVIDDCTKSLLLNLMAHEACPGSAEGFWVTSYVCFLDSLIDHSEDVKELRKKGILSNVLGSDQEVADLFNEISSFMVFDPNAYGNVKSSIEKHCKNVIKKWVAEWLNDHFSSPWTFLAFFGAIFALVLTFIQTYKTLYPGN 414          

Query:   14 SMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQ------------------------------SITDFIAH--NLMTNTEHRKGKH---VDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSW--GDSRRH-RKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFL-GKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFS-LPQN 452
            S+++    FD  L  + ++K++Q       Q   P+I RV P    ++ +   C++P +V++GP+HH  P+ +  E +K+ FA+ FV  S    D +F KV+    + RKCY  +  + +++ + + ++F+DGC +L    + +  + ++L                 ENQLP+++L  L+    + Q  E+                              +I+ F      L ++T+H K          +  AHLLE   ++ +    +     K  +   SW   DSR+     +   K+L+++GIH KPS T    D+ F    L G+L +P L +DDST    LNLVA E C    +D+ VTSY+CFMD+LID   DVKELR  GIL +  GSD++VA LFN++S  LVP+   Y KV +DI     N + + + +    Y    +TF+     I GL+ +AI+AY S +P N
Sbjct:   14 SLQQSTSRFDEWLKSMMDRKREQTGNY---QLGGPIIPRVPPTFRKIENN-SGCYDPSVVSIGPYHHGKPELKEMEDNKVTFASQFVMESQVAPDTMFCKVEGVASNARKCYTEDSTQKFEDKEFSQMMFLDGCFIL-HFFFCLSEQPEKLKMSNHHVSLVARDLFLLENQLPFEVLLELMSLRFNIQGGERVDLFEPFFKHIRSMPPRRESCREKLSKNLATISSFFRSLLKLFSSTDHPKSPTNELTAIHRKPAHLLELFHNKFVARSIIDAAGVKDHK---SWYKDDSRKSWSGRYYPAKDLRKAGIHFKPSKTSLFTDVSFTPTLLAGRLYIPPLRIDDSTKPLLLNLVAYEACLGTCDDW-VTSYVCFMDSLIDHHKDVKELRSKGILISTLGSDKQVAELFNEISDYLVPNPYAYSKVKRDI----ENHYRNGIKRWILHYKGPTYTFIFKYSFIFGLIVTAIKAYVSVVPMN 479          

Query:   44 QTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILI--------GSAKDSQI----------------WEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLG-KLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL-PQNRNS 455
            Q   P I +V  LL  ++++ Q C++P LV++GP+HH  P+ +  E+ K+ F + FV  SG   +D + KV     D R+CY  +  + +D++K   ++F+DGC +L  + + +  + ++L                 ENQLP++++  L+        G  ++  I                 ++ I  F    +    +   G     D    HLL  L  + +  E      S        W        ++RS K+L+  GI  +P+ T    D+ F  +F G +L++P + +++S  S  LNL+A E C D   +  VTSY CF+D+LI   +DVK L+  G+L N F  ++EVA+LFN+MSR+LVP+   Y  V + I     +     +A+  + YFS+PW+F+A + A   ++ + IQ+Y ++ P N N 
Sbjct:   40 QMQAPQIPKVPRLLRQIQSN-QKCYDPSLVSIGPYHHGKPELRDMEKLKVTFTSKFVDDSGICIEDFYCKVAEVAIDARRCYAEDSTDEFDDEKFTQIMFLDGCFILQFIFFLLR-RPEDLKMPGHQVVLVKRDLLLLENQLPFQVIWSLMNLRFGKGEGGGRNKLINDFIRHIRALPPRKESIKEMIKKFAGKCIWKQPKKTWGNKETEDHQPVHLLGLLHTDHINKEAC----SHCSTRSSDW-------YSYRSAKDLRTVGIRFRPNWTNAYSDVEFKSSFRGSRLILPPVTIEESFKSVLLNLIAYETCCDASGELWVTSYACFLDSLIQDVEDVKVLQSEGVL-NIFVREQEVADLFNQMSRNLVPNPYAYSDVKRQIELDRKSIIKKWVAEWLHDYFSSPWSFIALVAATFTIVLTVIQSYVAIFPLNNNG 463          

Query:   48 PLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIG---SAKDSQIWEQSITDFIAH----------------NLMTNTEHRKGKHVDGDKDY-----AHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLG-KLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL-PQNRNS 455
            P I +V  LL  ++++ Q C++P LV++GP+HH  P+ +  E+ K+ F + FV  SG   +D + KV     D R+CY  +  + +D++K   ++F+DGC +L  + + +  + ++L                 ENQLP++++  L+       +     + I DFI H                        ++ +   G+K+       HLL  L  + +  E      S        W        ++RS K+L++ GI  +P+ T    D+ F  +  G +L++P + +++S  S  LNL+A E C D   +  VTSY CF+D+LI   +DVK L+  G+L N F  ++EVA+LFN+MSR+LVP+   Y  V + I     +     +A+  +TYFS+PW+F+A + A   ++ + IQ+YF++ P N N 
Sbjct:    4 PQIPKVPRLLRQIQSN-QKCYDPSLVSIGPYHHGKPELRDMEKLKVTFTSKFVDDSGICIEDFYCKVAEVAIDARRCYAEDSTDEFDDEKFTQIMFLDGCFILQFIFFLLR-RPEDLKMPGHQVVLVKRDLLLLENQLPFQVIWSLMNLRFGKGEEGGGNKLINDFIRHIRALPPQQESFKEMIKKFAGKCIWKQPQKTWGNKETEEHQPVHLLGLLHTDHINKEAC----SHCSTRSCDW-------YSYRSSKDLRKVGIRFRPNWTNAYSDVEFKSSVRGSRLILPPITIEESFKSVLLNLIAYETCCDASGELWVTSYACFLDSLIQDVEDVKVLQSEGVL-NIFVREQEVADLFNQMSRNLVPNPYAYSDVKRRIELDRKSIIKKWVAEWMHTYFSSPWSFIALVAATFTIVLTGIQSYFAIFPLNNNG 423          

Query:   44 QTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHH-DNPKFQRAEQSKLK--FAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELN-TKXXXXXXXXXXXXXXENQLPYKLLKILI----GSAKDSQIWEQSITDF--IAHNLMTNTEHRKG---------------------KHVDGD-KDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLG-KLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL-PQN 452
            + +  +  RV  +     +  + C+ P +V++GP+HH D+P  + AE   LK      F + SG  R+ L+ KV+      +KCY     +   +     ++ +DGC +L  + +     F  L  +               ENQ+PY++LK L+    G A+  ++ E  + D   +  +   + E+ KG                       V G+     HLL+   +  + G   + EN  +       GD +    ++RS+ ELK  GIH  PS T    DI +     G  + +PR+++DDST S  LNL+A E C      F VTSY+ FMD+LID  +DVKELR  GIL N  GSD+EVA+LFN++S  +V D   Y  V   I K+C N      A+    +FS+PWTFLAF GAI  L+ + IQ Y +L P N
Sbjct:   36 EESSKICHRVPRIFRRNPSSNEDCYNPLVVSIGPYHHNDDPNHELAEMQSLKNEMVQQFANESGKTREVLYSKVEELAVSAKKCYDERSTKDLGDKAFTEMMLLDGCFILQFI-FCFLHDFQNLKLSNRVLAYFVKRDLFLLENQIPYEVLKSLMSLRFGDAEGKKLMEDFMDDVRGLPRDKSRDKENGKGLDCRFWSWRPAPKMNNQPGEIPQVPGEIPQPVHLLDFFHNRFMGGSRGQ-ENLSLK------GDGQW--SSYRSVMELKSVGIHFMPSKTDMYTDILYKSTMRGGTVTLPRIVIDDSTKSLLLNLMAHEACPGPAEGFGVTSYVYFMDSLIDHPEDVKELRKKGILSNVLGSDQEVADLFNEISSFMVFDPNAYGNVKSSIEKHCKNVIKKWAAEWLNDHFSSPWTFLAFFGAIFALVLTFIQTYKTLYPGN 468          

Query:   44 QTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDN-PKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCY-KPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPY----KLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRML-----------LSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFL-GKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL-PQNRNS 455
            Q   P I RV P + +     + C+EP++V++GP++H    + Q  E+SK      FV  S    +D++  V    +D R+ Y + E V+  D  +   ++F+DGC V+    Y +    + L                 ENQLP+     L+K+  GS ++     + I DFI H +      R+       K +   + R        +    E    G +L            S   S+     +    EL+  GIH KPS  +   D+ F   +L G+L +P L +D+ST S  LNLVA E C        VTSY+CFMD+LID  +DV+ LR  GIL    GS+EEVA LFN++++ LVP+   + KV  DI  +  N     +A+   TYFS+PW+F+  + A + +  +AIQ+YF+L P N N 
Sbjct:   11 QQQGPRIPRV-PQIFSGIGSNKKCYEPKVVSIGPYYHGKLDRLQEMEKSKCNMVRGFVQQSKKLIEDVYQTVVDVAEDARRYYVEDESVKLDDMTEFTRMMFLDGCFVI-QFMYCLLRDHENLKMSSHAAALVTRDLLLLENQLPFLVLRSLMKLRFGSDEEGM---KLIKDFIKH-IRAMPRQRESCWKKISKFFRKTIPRRALNYSAKDPAMGEYYGAGHLLELFHMHFVDKNFSVDSSKTSLYRYHPAMELRTVGIHFKPSKARQFTDVQFKPTWLAGRLKIPPLTIDESTKSMLLNLVAYEACLGDNKKLWVTSYICFMDSLIDHPEDVRVLRSQGILLVTLGSEEEVARLFNEVAKYLVPNPHAFNKVKNDIESHFRNTIKRWVAEHVDTYFSSPWSFITLVAASLTIALTAIQSYFTLFPLNNNG 435          

Query:   68 FEPRLVALGPFHHDN--PKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQ-IWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSW------GDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCN-FLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFS 448
            ++P +V++GP+H+ +   K   AE+ K++ A  FV  S  + + L+ +V    ++ ++ Y+   +  +D+++   ++F+DGC +L  +R  +    +  N                ENQLP+ +LK L+    D +    + I DF++  ++  + H++                                   R +L+W           +        +L++ GI+ KPS T  L D+ F  + F   L +P + ++ +T S  LNLVA E    F +D  VTSY+CF+D+LI+ A+DVK LR  GIL NY G D++VA+LFN++     P+   Y  V  +I+  C++ W   +A+   TYFS+PW F+AF+ A  GL+ +A Q Y++
Sbjct:   87 YKPSVVSIGPYHYKDRQNKLHEAEKLKVQMAREFVLYSKKDMEILYSEVAKVAENAKRFYEGSSIRCFDDEQFTQMMFLDGCFILQFIR-CVSTTDNIKNMSDQQIFHVKQDLLLLENQLPFPVLKSLMSLTPDGKDHGMKIINDFLSLQILQQSNHQR-----------------------------------RPVLTWLVKGYLLLLLIYTTVAYPFHDLQKVGIYFKPSKTNTLMDVEFVSSIFYATLKLPSITIEKATRSMLLNLVAYETAA-FLDDLWVTSYICFIDSLINDAEDVKVLRSNGILINYLGPDQKVADLFNQIGHSREPNTNVYNDVKGEINLSCDSIWKKWIAECLQTYFSSPWAFIAFVAAATGLVLTATQTYYT 440          

Query:    1 MDTIIEMPAEPLNSMEEKMKEFDSALHEVQNQKQQQAQGS--------------TPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNP--KFQRAEQSKLKFAALFVHVSGT-NRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIG--SAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCN-FLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQG-RYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            +D +     +PL++  E+  +   A+ E+Q    Q  + S              T  + + P+I +V      +K + + C++P +V++GP+H+ +   K    E+ K++ A  FV  S   + + L+ +V    ++ ++ Y+   +  +D+++   ++F+DGC +L  +R  M+ K D  + +              ENQLP+ +LK L+   +  D +  E +I DF+   ++  ++ R+   V       +L  +               SK+G         +R    + S K+L++ GIH KPS T  L D+ F  + F   L +P + ++ +T S  LNLVA E    F +D  VTSY+CF+D+LID A+DVK LR  GIL NY G D++VA+LFN++ R L P+    Y  V + I+  C++ W   +A+   TYFS+PW F+AF+ A   L+ +A Q Y+++
Sbjct:   11 VDPLTNRQEDPLSNRPEQGSKM--AMSEIQGTSSQTNERSLWLSGIMRGVEGAKTKQRYSGPMIPKVPD---KLKHENKECYKPSVVSIGPYHYKDRQNKLHEVEKLKVQMAREFVLDSKIKDIEILYSEVAKVAENAKRFYEGSSISCFDDEQFTRMMFLDGCFILQFIRGVMDNKLDMSDQQ---IILVKQDLLLLENQLPFSVLKSLMSLKNDGDDRGKEININDFLLLQILQQSDQRRPVWVLSWLVKGNLFPK---------------SKLG---------KRGHNLYYSAKDLQKVGIHFKPSKTSTLMDVKFVSSIFYATLKIPSITIEKATRSMLLNLVAYETAA-FLDDLWVTSYICFIDSLIDDAEDVKVLRSKGILTNYLGPDQKVADLFNQIGRSLEPNTNIVYNDVKRKINVSCDSTWKKWIAEWLQTYFSSPWAFIAFVAAAAVLVLTATQTYYTV 447          

Query:   44 QTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDND-KLAWVLFVDGCAVLCAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWE------QSIT-DFI-----------------AHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCN-FLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFS 448
            Q   P   +V P L +++ +   C++P +V++GP+HH   K +  E+ K  +A  FV       + ++ KV+A +   R  Y PEDV    ND K   ++F+DGC +L  + Y + G+ + L                 ENQLP+ +L  L    + S  W       QS++ D+                  AH   T  E  K    D ++  AHLL     ELL  + M    SK      + G SR H   + S K LK++GI  +   T  + D+ F  + F G L +P +++++ST S  LNLVA E      +   V+SY+CFMD+LID A DV+ELR  GI+ NYFG+D++VANLFN M   +  D   Y  +   I++ C +     + +   TYFS PWT +  + A  GL  +A Q Y++
Sbjct:   36 QRKGPDFPKVPPTLRDIQQNSD-CYDPSVVSIGPYHHGKKKLEEMEKLKETYARQFVKDKDKPNEQIYGKVEAVLSIARNSY-PEDVTYNLNDEKFNKMMFIDGCFILQFMHY-LIGENEVLKMSDQQIFHVKRDLLLLENQLPFAVLHSL---RRQSYQWATHLLRGQSVSLDWSPPPPRGKSGTRDDEPQPAHPPPTRKE--KSGTRDDERLPAHLL-----ELLYYKSM-YHYSKSNHKKAAKG-SRGH-CLYYSAKNLKKAGILFRARWTGAITDVKFKSSIFWGTLKVPPIIIEESTKSLLLNLVAYETSAAL-DQLWVSSYICFMDSLIDDAKDVEELRSNGIIINYFGADQKVANLFNDMGISMTHDTAAYNDIKIKINEQCESTVKRWVYESKRTYFSNPWTAITVLAASFGLALTATQTYYT 449          

Query:   36 QAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRM---LLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLG-KLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNN-----------PWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFS 448
            +++     Q  +  + RV      MK +   C+EP +V++GP+HH   + +  E+ K + A  FV  S    ++++ KVK  + D RKCY  E    ++++K   ++F+DG  +L  V   ++    + N +              ENQLP+++L  L+   K                        K  H+ G+   +      R  +  GEE+  E  + GR    + SW         + S++ELK  GI   PS T+   D+ F    LG  L +P L +++ T    LNL A E C  +  D   TSY+CFM +LID  +DVKELR  GIL    GSD+ +A +F +++ +L P+   Y KV + +  +  +           P++ A+ +  + Y               G+  SAIQAY +
Sbjct:    3 ESRAGNSNQVNEIEVPRVPSEFRKMKENTD-CYEPLVVSIGPYHHGKKELKEMEKLKAEMAGQFVKDSRVTAEEMYSKVKELVSDARKCYAEESTRQFNDEKFTQMMFLDGYFILQVVSENLK----QQNLRKEEVASVRRDLFLLENQLPFRVLIPLMRIYKS-----------------------KADHIAGEDKSSS-----RQFVYVGEEL--ERERGGRRYGEITSWN-------RYYSVEELKNVGISFMPSNTRVFTDVKFKNTLLGGALCIPPLSIEEETKPLLLNLAAYETCAGWYYDMYCTSYVCFMRSLIDKPEDVKELRSKGILRTTIGSDDRIAQIFKEITTNLAPNPTAYTKVKRSVESHYRSSVKRWILENKGPFSRAVVKYSFIY---------------GIAVSAIQAYLA 373          

Query:   21 EFDSALHEVQNQKQQ---QAQGSTPP---QTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHD-NPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHN-LMTNTEHRKGKHVDGDKDYAHLLERLRDELL-TGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFL-GKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            E    +HE  + +++   + +   PP   +  KP IQRV P +L     F   +EP + ALGPFHH   PK++ AE+ KLK AA FV  S  N  DL  KV+  I++LRKCY  E  + Y+++ LAW+LFVDGC+ L  +      K+DEL                 +NQLPY+LL++L+ S++  +  ++SI DF+  N L  N ++ + K         HLLE LR  +L T    K + +K+               +FR+++EL+ +GIH +PS + +L+ I F  +   G L +P++ VDDST  KF+NL+A EMC DF NDF VTSY+CF+D+LID  DDVK LR   IL N+ G+DEEVA LFN++  DLVP+   Y  V   I K+  N     +AQ ++ +FS+PWT +AF+GA++ L  S +Q  +S+
Sbjct:   31 EVSITIHEEASTREERLNKLREEAPPIQAEKVKPKIQRV-PFMLRQDTKFDKYYEPIVAALGPFHHTRKPKYEHAEKIKLKLAANFVKDSKQNDADLLKKVEDNINELRKCYDEEATKDYEDEFLAWMLFVDGCSTLEFIY-----KYDELEN---------FQIKRDQNQLPYQLLQLLMSSSQIHKKLKKSIDDFVWRNSLAQNQQNPEAKPT-------HLLELLRTTMLGTSPSEKTKGTKLPH-------------SFRNVQELQAAGIHFRPSNSNSLRSISFISSLCHGILYLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDHPDDVKHLRKKLILQNFLGNDEEVAQLFNEIGTDLVPNDDIYYSVKDQIEKHYGNWGNRVMAQFFHEHFSSPWTVVAFLGALLALGSSIVQTVYSV 434          

Query:   41 TPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLK-----------------------ILIGSAKDSQIWEQSITDFIAHN------------------------------LMTNTEHRKGKHVDGDKDY-------------------AHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHF--YCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLP 450
            +P  +++P IQ+V P +L    +F   + PR VA+GPFHH NP+ + A++ KL     F    G   +DL+ K++ +I +LR+CY  E  E  D+  LAW+LF+DGC+ L  + Y +  + +E   K              ENQ+PY++L+                       I++   K S+  EQ     I  N                              L T+T+ ++   V  D ++                    HLL+ LR  +L   +  +   K+G            ++TFR+++EL  +GIH +PS T  L DI F  +C F G L +P + VDDST  KF+NL+A EMC DF+ND+ V SY+ F+D LID ADDVK+LR   +L N+ GSD+EVA LFN++  DLVP+   Y +V  ++ K+    W   ++Q  + +FS+PWT LAF+G +  L  S IQ ++++P
Sbjct:   22 SPIPSSQPKIQKV-PFMLRDHKNFDKYYVPRAVAIGPFHHGNPRCKLAQKYKLMLTLKFADFVGQKDEDLYKKIEEKIKELRECYVKEATEHIDDGTLAWMLFLDGCSTLQFI-YSLMNEHEEFEIKRDQVAFAQQDLFLLENQIPYQVLELLMSSSDKREVLKHAIESFVQMHIIVPVEKQSKGQEQKHQPGITENREQKQEPDTTSSTEHKVDITENTETKQQDGLTTDTDQKQQPGVTTDANHKQQPGVTTDANQKQQPEEPTHLLDLLRKRILGPPKKDVSKKKVGE---------SPKQTFRNVQELSAAGIHFQPSKTNFLGDISFKSHC-FAGFLSLPPISVDDSTGPKFMNLIAYEMCPDFQNDYGVASYIGFLDALIDHADDVKKLRSASVLFNFLGSDKEVAQLFNEIGTDLVPNTAIYLRVKAELEKHYKTKWKTWMSQFCHDHFSSPWTILAFLGVLSALGLSGIQTWYTVP 493          

Query:   44 QTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIA-HNLMTNTEHRK----------------------GKHV-------DGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHR--------KTFRSIKELKESGIHVKPSTTKNL-KDIHFYCNFL-GKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFS 448
            Q  KP IQRV P +L    +FQ  +EPR+ A+GPFHH  PK+++AE+ K   AA FV  SG N  DL  KV+  I  L++CY  E  + YD+D LAW+LFVDGC+ L  + Y  E K +    K              ENQLPY+LLK+L+ S+   +  ++SI  F+  H +    E++K                      G+H        + ++    +   ++ +    E   +    + RML   G + R          ++FR+++EL+ +GIH +P    +L  DI F      G L +P++ VDDS   KF+NL+A EMC DF+NDF VTSY+ F+D+LID  DDVK LR   IL N  GSDEEVA LFN++  DLVP+   Y  V   I  +    W   +AQ ++ +FS+PWT LAFIG ++GL  +A Q +++
Sbjct:   59 QNAKPKIQRV-PFMLQDHKNFQKYYEPRVAAIGPFHHGKPKYEQAEKVKRHLAANFVKDSGQNEADLLKKVEENIKRLKECYDEEATKKYDDDSLAWMLFVDGCSTLEFI-YKYE-KLESFKIKRDQVAFAEQDMFLLENQLPYQLLKLLMSSSSKHEELKESIERFVQMHGVAPPDENQKSQQDARKPEQKPPQPGAGLARPGQHPAVTNINREENQHSQSIAITIKPKPTEPEPTHLLELLLTRML---GYAPRKSEPSVNLGAQSFRNVQELQAAGIHFRPRKEGSLLGDIDFKSYICCGFLYLPKIKVDDSMGPKFMNLIAYEMCPDFQNDFGVTSYISFLDSLIDHPDDVKHLRKKHILRNLLGSDEEVAQLFNEIGTDLVPNNAIYRIVKSKIEDHYQTMWKKWVAQFFHEHFSSPWTILAFIGVLLGLGMTAAQTWYA 497          

Query:   41 TPP---QTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDN-PKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNT---KXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNT------------EHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHF--YCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
             PP   +  KP IQ+V P +L     F   +EP + ALGPFHH   P+++ AE+ KLK AA FV  S  N  DL  KV+  I++LRKCY  E  + YD++ LAW+LFVDGC+ L  +      K+DEL     K              ENQLPY+LL++L+ S++  +  ++SI +F+  N                 E R     + + +  HLLE LR  +L  E  K E                         EL+ SGIH KPS   +L+ I+F  +  F G L +P++ VDDST  KF+NL+A EMC DF NDF VTSY+CF+D+LID  DDVK LR   IL N+ G+DEEVA LFN++  DLVP+   Y  V   I  + +N     +AQ ++ +FS+PWT +AF+GA++ L  S +Q  +S+
Sbjct:   54 APPIQAEKVKPKIQKV-PFMLRQDKKFDKYYEPIVAALGPFHHARLPQYEYAEKIKLKLAANFVRDSKQNDADLLKKVEDNINELRKCYDEEATKKYDDEFLAWMLFVDGCSTLEFIY-----KYDELENFQIKRDQVAFVEHDIFLLENQLPYQLLQLLMSSSQIHKELKKSIDEFVGRNSPAAAPADQNGQNPEAEEQRSQPGQEVEAEPTHLLELLRTTMLPYESEKKE-------------------------ELQASGIHFKPSEGNSLRSIYFGSFHLFHGILHLPQIKVDDSTRPKFMNLIAYEMCPDFHNDFGVTSYICFLDSLIDQPDDVKHLRKKQILRNFLGNDEEVAQLFNEIGTDLVPNNDIYSSVKDQIEDHYDNWGNRVMAQFFHEHFSSPWTGIAFLGALLALGSSIVQTVYSV 452          

Query:   64 FQICFEPRLVALGPFHHDNPKF-QRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELN---TKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHN---------LMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKN-LKDIHFYCN-FLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAY 446
            +Q  +EPR+ A+GPFHHD  ++ Q+ E+ KL+ A  FV  S  N  DL  KV   I +LR+CY  E    Y +D LA +LFVDGC+ L  +      K+D+L     K              ENQLPY+LLK+L+ S+   +  E SI  F+  +          +     R+   +  + +  HLLE LR  +L     K E S   R            ++F +++EL+ +GI  +P    + L DI+F    +LG L +P++ VDDS A KF+NL+A EMC DF+NDF VTSY+ F+D+LI+ ADDVK LR   IL N  GSDEEVA LFN++  DLVP+   Y  V + I  +    W   +AQ +Y +FS PW  LAFIG + GL  SA+Q +
Sbjct:    8 YQRYYEPRVTAIGPFHHDKFQWCQQGEKLKLQLAVNFVRDSKQNEADLLKKVDVNIKELRECYAQEPTGRYVDDDLALMLFVDGCSTLEFIY-----KYDDLECFEIKSDQVALAEQDIFLLENQLPYQLLKLLMSSSSIHEDLEDSIERFVLMHSTFAPYQPQRVAGAARREDVRISTEPEPTHLLELLRTRILGYPPKKSEPSVNIR-----------PQSFHNVQELQAAGIQFRPVRGPSVLGDIYFKSFLWLGFLYLPKIKVDDSMAHKFMNLIAYEMCPDFQNDFGVTSYIGFLDSLINYADDVKHLRKNHILRNLLGSDEEVARLFNEIGTDLVPNNAIYRNVKRMIEDHYQTRWKKWMAQFFYDHFSKPWI-LAFIGVLSGLGLSAVQTW 388          

Query:    3 TIIEMPAEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDK-LAWVLFVDGCAVL-------CAVRYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSW-GDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLV 389
            ++ E+  + L+S+E+ + +   A  E +         S    ++K  IQ V P +L   ++   CFEPR++A+G  HH   K   AE+ K   AA F+   G   + L++ ++  I  ++ CY  E  + YD+D+ LAW+LF+DGC+ L       C   +GM         K              ENQLPY++LK+L  S++      +++  F    L+     R+G+     K   HLL+ LR E+L   E            LS+ G       +FR+++ELK +G+H                 F   L +P   +++   S FLNL+A EMC DF+NDF VTSY  F+ +LI   +D K+LR   IL N  GSDE +A+ F+++  DLV
Sbjct:    6 SVNELSIKMLDSVEQGVDKLRDA--ERRLPTPDGNDNSATSNSSKSKIQSV-PRILRSHSNLVKCFEPRVLAMGQIHHGECK--EAEELKYTLAADFIKDCGCTYNHLYETIQKNILKIKDCYDSETTKCYDDDEALAWMLFIDGCSTLQFIHKYDCLEDFGM---------KATQVAFARLDLFLLENQLPYRVLKLLKRSSRKEDELNRNMKRFAKCRLLQQKSQRRGEL----KYSTHLLDFLRKEMLGPSEE-----------LSYRGGKEDCSPSFRNVQELKAAGVH-----------------FRRFLSLPP--INEDAMSSFLNLIAYEMCPDFRNDFAVTSYFGFLSSLIAHPEDAKQLRSARILSNLRGSDEALADFFHEIGPDLV 353          

Query:   68 FEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDND-KLAWVLFVDGCAVLCAVR--------YGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIG--SAKDSQIWEQSITDFIAHNLMTNTEHRK-GKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPD-QGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            ++P++   GP+H D+      E  K +    F+   G   +   + +   + DL+  Y   D    D+  +   ++ +DGC +L  VR        Y +       + K              ENQLP  +L  L+   S KD    E S+T  +     + T     GK +       H+L+  R  LL  E       K GR         RH     S  EL E+GI  K S T +LKDI F     G L +P ++VDD+T S FLNL+A E       + EVTSY+ FMD +ID+A DV  L   GI+ N  GSD+ VANLFN +S+D+  D +   + V K ++ YC  PW +  A + +TYF  PW  ++ I  +   + +  Q  +S+
Sbjct:   44 YKPQVATFGPYHFDH--LNTTEVHKHRALLHFLKRCGKPFELFVNALTEVVQDLKDSYDQLDPGWKDDTARFLQLMILDGCFMLEVVRIASNILDDYALNDPVFSNHGKLHIIPYIKRDMLMIENQLPMLVLNKLVEVESNKD----ELSVTRLLLKFYYSGTSASNMGKCL-------HVLDVYRKSLLQSEP----QCKTGR--CPPAPVNRHDVIIWSATELNEAGIRFKKSKTGSLKDISFSG---GILRLPVIIVDDTTESMFLNLIAFERFHVGAGN-EVTSYIFFMDNIIDNARDVALLHSKGIVQNALGSDKAVANLFNSLSKDITLDPESSLDAVHKKVYHYCRKPWNEWRANLIHTYFRNPWAVISLIAGVFLFVLTIAQTGYSI 415          

Query:   29 VQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEG-------KFDELNTKXXXXXXXXXXXXXXENQLPY----KLLKILIGSAKDSQIWEQSITDFI-----AHNLMTNTEHRKGKHVDG---------DKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDS-----RRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCR-DFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPD--QGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            ++++ +Q  Q        K  I RV P  L    D  I   P++V+LGP+HH   + ++ ++ K +     +  +  N     D +K   +  R CY+        +++   ++ +DGC VL   R   EG       + D +                 ENQLP     +LL +  G  +   +  +    F          +T ++  K +   G         D+   H L+  R  LL           I +    W  +     +R ++    + EL+E+GI  K   T    D+ F     G L +PRLL+ D T S FLNL+A E C  D  ND  +TSY+ FMD LI+S  DV  L   GI+ ++ GSD EVA+LFN++ +++V D       ++ +D+++Y N+ W    A + + YF+ PW  L+F+ A++ L  +  Q ++ +
Sbjct:   85 IKDKLEQAGQDDAAGTWAKLCIYRV-PHYLREGDDKAIV--PQIVSLGPYHHGRRRLRQMDRHKWRSLHHMLKRNNQNIQLYLDSIKEVEEKARACYEGPVAMGISSNEFVEMMVLDGCFVLELFRGAAEGFKQLGYPRNDPIFAMRGSMHSIQRDMIMLENQLPLFILDRLLGLQFGDPEQKGLVAKLALRFFDPLMPTDEPLTKSDRSKLESSLGYANTFDPLSDQGGLHCLDVFRRSLLRRGLQPTPRVWIKK----WSHANRVADKRRQQLIHCVTELREAGIKFKKRKTDRFWDVKFEN---GILRIPRLLIHDGTKSLFLNLIAFEQCHLDCSND--ITSYVIFMDNLINSPQDVGYLHYCGIIEHWLGSDAEVADLFNRLCQEVVFDINDSYLSRLSEDVNRYYNHRWNAWRASLKHNYFNNPWATLSFVAAVVLLFLTFAQTFYGV 526          

Query:   68 FEPRLVALGPFHHDNPKFQRAEQSKLKFAALFV---HVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVR-YGMEGKFDE---LNTKXXXXXXXXXXXXXXENQLPYKLLKIL-----IGSAKDS-QIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHR------KTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGR--YEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            + P+++++GP+H   P+ +  E+ K ++    +      G   +D F  ++    + R+CY  E +     D+   ++ +DGC ++   R +G   KF+E   L +               ENQ+PY +L++L     +   KD+ +       +F  H+ M   +H    H +      HLL+ LR  ++                   G    HR       T   + +L+ +GI ++P   ++   I F     G + MP + +DD  +S  LN VA E C    +   +T+Y   +D L+++  DV+ L    I+ N FG+D +VA   N + +D+  D  R    K+  D+H Y  N W    A   YTYF TPW+ ++   A+I L+ + +Q ++++
Sbjct:   64 YNPQILSIGPYHRGEPRLKMIEEHKWRYLGSLLSRTEAKGLTLNDYFKALEPLQAEARECYS-ESINL-STDEFIEMMVLDGCFIIELFRKFGRLVKFEEYDPLVSMVWIISFLVRDLLRLENQIPYLVLEVLFDLTTLPEHKDNGKTLSLLALEFFNHH-MQRPDHVIQNHQNLTG--VHLLDLLRASVIPP-----------------GHDEPHRGNIIPTHTIHCVSKLRRAGIKLRPCEGESFLVIKFK---RGVIEMPTITIDDFMSSFLLNCVAYEQCHKSCSK-HITTYATLLDCLVNTYKDVEYLCDRNIIENCFGNDGDVARFVNNLGKDVAFDMDRCYLAKLFNDVHHYYGNSWHVQWASFKYTYFDTPWSCISAFAALILLIMTLLQTFYTV 440          

Query:   68 FEPRLVALGPFHHDNPKFQRAEQSKLKFAA-LFVHVS--GTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDG---CAVLCAV-RYGMEGKFDELNTKXXXXXXXXXXXXXXENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKG----KHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVP---DQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLPQNRNS 455
            ++P +V++GP+H+ +      +Q K +F   L V     G N DD    V +  +D+R+CY  E +     D L  V+ +DG     + C V R       D +                 ENQ+P+ +L+ L   +K S+    S    +A    +    R      +HV  +    HLL+ LR   +     +   ++  +     G++    +  +S K+L  +GI  K     +  DI F CN  G L +P + +DD     FLN VA E C    +   +T+Y   M  LI +  D   L    I+ NY G+DEEVA+ F  + +D VP   D+    K+ KD+++Y  N W    A   + YF  PW+FL+ + A++ LL +AIQ +F++    NS
Sbjct:   61 YQPHIVSIGPYHYGDTHLDMMQQHKWRFLRDLLVRTPSPGPNLDDYRQVVASMEEDIRRCYS-ETINLCGQD-LVEVMVLDGLFTIELFCKVGRLSPSDPDDPIFNLAWIFPNLIRDLLRLENQIPFIVLQTLFDKSKSSREDSNSSLAQLALEFFSFAVERPDEVLKQHVSVEA--KHLLDLLRLSFIPEPHHRSPQNQNPK-----GNTSPLVQFIQSAKKLHLAGIKFKEREANSFLDIRF-CN--GVLEIPNITLDDLRTDIFLNFVAFEQCYSHCSK-HITTYAALMSCLISTPVDAAFLSDKNIIENYLGTDEEVAHFFKNLGKD-VPFDIDESYLCKLFKDVNEYHRNIWHVRWAGFRFKYFDNPWSFLSAVAAVVLLLLTAIQTFFTVYDYFNS 448          

Query:   70 PRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDD-LRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFA--------QLDLFLLENQLPY----KLLKILIGSAKDSQIWEQSITDFI-----AHNLMTNTEHRK-----GKHVD--GDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGD-SRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLV--PDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            P+ V+LGP+HH   + +  E+ K + A   V      R +++     ++++  R CY  E   +   ++   +L +DGC VL   R  +EG F E+    +  +FA        Q D+ +LENQLP     +LL++ +G+   + I       F          +T  +  K      K +D  GDK   H L+  R  LL         S + R+  +     +R ++    + EL+E+G+  +   T    DI F     G L +P+LL+ D T S F NL+A E C   ++   +TSY+ FMD LI+S++DV  L   GI+ ++ GSD EVA+LFN++ +++V  P      ++  D+++Y N  W    A + + YF+ PW + +F  A+I LL +  Q+++++
Sbjct:  132 PQTVSLGPYHHGKKRLRPMERHKWR-ALNKVLKRLKQRIEMYTNAMRELEEKARACY--EGPISLSRNEFTEMLVLDGCFVLELFRGTVEG-FTEIGYARNDPVFAMRGLMHSIQRDMIMLENQLPLFVLDRLLELQLGTQNQTGIVAHVAVKFFDPLMPTGEALTKPDQSKLMNWLEKSLDTLGDKGELHCLDVFRRSLLQSSPTPNTRSLLKRLTRNTRVVDKRQQQLVHCVTELREAGVKFRKRKTDRFWDIEFKN---GYLEIPKLLIHDGTKSLFSNLIAFEQCH-IESSNHITSYIIFMDNLINSSEDVSYLHYCGIIEHWLGSDSEVADLFNRLCQEVVFDPKDSHLSRLSGDVNRYYNRKWNVLKATLTHKYFNNPWAYFSFSAAVILLLLTLCQSFYAV 531          

Query:   29 VQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFA--------QLDLFLLENQLPY----KLLKILIGSAKDSQIWEQSITDF--------IAHNLMTNTEHRKGKH----VDGDKDYAHLLERLRDELLTGE---EMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCR-DFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPD-QGRY-EKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFS 448
            ++++ +Q  + +      K  I RV    L++K   +  + P+ V+LGP+HH +   +  +  K +   + +  +    +   D +K   +  R CY  E      ++K   +L +DGC VL   R   EG F +L    +  +FA        + D+ +LENQLP     +LL++ +G+   + +  Q    F        ++   + N++    K      D +K+  H L+  R  LL      + ++  S+  R  L     +R ++    + EL+E+GI  K   +    DI F     G L +P+LL+ D T S F NL+A E C  D  ND  +TSY+ FMD LIDSA+D++ L    I+ ++ G+D EVA++FN++ +++  D +  Y  ++   + +Y N  W    A + + YFS PW + +F  A+I LL +  Q++F+
Sbjct:   94 IKDKMEQVMRDAATTSWDKICIYRVP---LSLKKSDKNSYFPQAVSLGPYHHGDEHLRPMDYHKWRAVNMVMKRTKQGIEMYIDAMKELEERARACY--EGPIGLSSNKFTQMLVLDGCFVLDLFRGAYEG-FSKLGYDRNDPVFAMRGSMHSIRRDMLMLENQLPLFVLNRLLELQLGTQYQTGLVAQLAVRFFNPLMPTYMSSTKIENSQENNNKFFNPIADKEKEELHCLDVFRRSLLQPSLKPDPRLSRSRWSRKPLV--ADKRQQQLLHCVTELREAGIKFKRRKSDRFWDIQFKN---GCLEIPKLLIHDGTKSLFSNLIAYEQCHIDSTND--ITSYIIFMDNLIDSAEDIRYLHYYDIIEHWLGNDSEVADVFNRLCQEVAFDLENTYLSELSNKVDRYYNRKWNVLKATLKHKYFSNPWAYFSFFAAVILLLLTLFQSFFT 530          

Query:   70 PRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYK-PEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEG-------KFDELNTKADLLIFAQLDLFLLENQLPY----KLLKILIGSAKDSQIWEQSITDFIAHNLMTNTE--HRKGKHVD--------GDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLV--PDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            P+ V++GP+HH     +  E+ K +   + +  +  N +   D +K   ++ R CY+ P D++  ++++   +L +DGC VL   +  ++G       + D +  K  L+   Q D+ +LENQLP     +LL +  G+   + I  +    F    LM  +E   +  + +D        GD    H L+     L+   E   + +    M +      + ++    + EL+ +G++     T  L DI F     G L +P+LL+ D T S F NL+A E C   ++   +TSY+ FMD LI+S+ DV  L   GI+ ++ GSD EVA+LFN++ ++++  P  G   ++ +++++Y +  W    A +   YF+ PW + +F  A+I L  +  Q++F++
Sbjct:  109 PQTVSIGPYHHGKVHLRPMERHKWRAVNMIMARTKHNIEMYIDAMKELEEEARACYQGPIDMK--NSNEFTEMLVLDGCFVLELFKGTIQGFQKIGYARNDPVFAKRGLMHSIQRDMIMLENQLPLFVLDRLLGLQTGTPNQTGIVAEVAVRFFK-TLMPTSEVLTKSERSLDSQEKSDELGDNGGLHCLDVFHRSLIQSSETTNQGTPYEDMSMV----EKQQQLIHCVTELRGAGVNFMRKETGQLWDIEFKN---GYLKIPKLLIHDGTKSLFSNLIAFEQCHT-QSSNNITSYIIFMDNLINSSQDVSYLHHDGIIEHWLGSDSEVADLFNRLCKEVIFDPKDGYLSQLSREVNRYYSRKWNSLKATLRQKYFNNPWAYFSFSAAVILLFLTFFQSFFAV 501          

Query:   70 PRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFA--------QLDLFLLENQLPY----KLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKG------------KHVD--GDKDYAHLLERLRDELLTGE---EMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCR-DFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQ--GRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLL------FSAIQAYFSLP 450
            P+ V+LGP+HH   + +  ++ K +     +  +        D ++   +  R CY  E   +  +++   +L +DGC VL   R  +EG F EL    +  +FA        Q D+ +LENQLP     +LL++ +G+   + +  Q    F    + T+    K             K  D   D    H L+  R  LL      E ++   +  R      D RR ++    + ELKE+GI  +   T    D+ F     G L +PRLL+ D T S FLNL+A E C  D  ND  +TSY+ FMD LIDS +DV  L   GI+ ++ GSD EVA+LFN++ +++V D       ++  ++++Y ++ W    A + + YF+ PW  ++F  A+I L+      F A+ AY+  P
Sbjct:  122 PQTVSLGPYHHGKKRLRSMDRHKWRAVNRVLKRTNQGIKMYIDAMRELEEKARACY--EGPLSLSSNEFIEMLVLDGCFVLELFRGAVEG-FTELGYARNDPVFAMRGSMHSIQRDMVMLENQLPLFVLNRLLELQLGTRNQTGLVAQLAIRFFDPLMPTDEPLTKSGQSKLENSLARDKSFDPFADMGELHCLDVFRRSLLRSSPKPEPRLTRKRWSRNTRV-ADKRR-QQLIHCVTELKEAGIKFRRRKTDRFWDMQFKN---GYLEIPRLLIHDGTKSLFLNLIAFEQCHIDSSND--ITSYIIFMDNLIDSHEDVSYLHYCGIIEHWLGSDSEVADLFNRLCQEVVFDTEDSYLSRLSIEVNRYYDHKWNAWRATLKHKYFNNPWAIVSFCAAVILLVLTFSQSFYAVYAYYKPP 530          

Query:   70 PRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYK-PEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFA--------QLDLFLLENQLPY----KLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKH-----------VDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDS---RRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCR-DFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLV--PDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFS 448
            P+ V+LGPFHH N      ++ K +   + +  +  + +   D +K   D  R CY+ P D+ +   +K + +L +DGC VL   R   EG F EL    +  +FA        Q D+ +LENQLP     +LL+I +G    + +  +    F    + T+    K               D DK   H L+  R  LL          ++ RM  SW      +R ++    + EL+E+GI  +   T    DI F     G L +P+LL+ D T S F NL+A E C  D  ND  +TSY+ FMD LIDS++DV+ L   GI+ ++ G+D EVA+LFN++ +++   P      ++   + +  +  W    A + + YF+ PW + +F  A++ L+ +  Q++F+
Sbjct:  158 PQTVSLGPFHHGNKHLLPMDRHKWRAVNMVMARTKHDIEMYIDAMKELEDRARACYEGPIDLSS---NKFSEMLVLDGCFVLELFRGADEG-FSELGYDRNDPVFAMRGSMHSIQRDMVMLENQLPLFVLNRLLEIQLGKRHQTGLVSRLAVRFFDPLMPTDEPLTKTDDSLEQDKFFNPIADKDKGELHCLDVFRRNLL--RPCSNPEPRLSRMRWSWRTRVADKRQQQLIHCVTELREAGIKFRTRKTDRFWDIRFKN---GYLEIPKLLIHDGTKSLFSNLIAFEQCHIDSSND--ITSYIIFMDNLIDSSEDVRYLHYCGIIEHWLGNDYEVADLFNRLCQEVAFDPQNSYLSQLSNKVDRNYSRKWNVLKAILKHKYFNNPWAYFSFFAALVLLVLTLFQSFFT 555          

Query:   50 IQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYK-PEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFA--------QLDLFLLENQLPYKLLKILIGSAKDS---QIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLV--PDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            I RV P L   + +    + P++V++GP+HH +      E+ K +   + +  +  + +   D +K   +  R CY+ P ++   + ++   +L +DG  ++   +   EG F E+    +  +F         + D+ +LENQLP+ +LK L+   +     ++  Q    F    L T       + V  ++   H L+ LR  LL       E+  +         +++ ++    + EL+ +G+      T +  DI F     G L +P+LL+ D T S FLNL+A E C   K+  ++TSY+ FMD LI+S++DV  L   GI+ N+ GSD EV++LFN + ++++  P+ G    +  +++ Y    W    A + + YF+ PW + +FI A+  L+F+  Q++F++
Sbjct:  106 IYRVPPYL---QENDTKSYMPQIVSIGPYHHGHKHLMPMERHKWRAVNMVMARAKHDIEMYIDAMKELEEKARACYQGPINM---NRNEFIEMLVLDGVFIIEIFKGTSEG-FQEIGYAPNDPVFGMRGLMQSIRRDMVMLENQLPWSVLKGLLQLQRPDVLDKVNVQLFQPFFQPLLPT-------REVLTEEGGLHCLDVLRRGLLQSSGTSDEDMSMV--------NKQPQQLIHCVTELRNAGVEFMRKETGHFWDIEFKN---GYLKIPKLLIHDGTKSLFLNLIAFEQCH-IKSSKKITSYIIFMDNLINSSEDVSYLHHYGIIENWLGSDSEVSDLFNGLGKEVIFDPNDGYLSALTGEVNIYYRRKWNYLKATLRHKYFNNPWAYFSFIAAVTLLIFTFCQSFFAV 493          

Query:   70 PRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFA--------QLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGD---SRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLV--PDQGRYEKVIKDIHKYCNNPWTDALAQVYYTY---FSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
            P  V+LGP+HH +   +  +  K +   + +  +    +   D +K   +  R CY  E      ++K   +L +DGC VL   R   EG F +L    +  +FA        + D+ +LENQLP  L+   + S K               N   N         D DK+  H L+  R  +L    +K E  ++ R   SW      +R +K    + EL+E+GI  K   +  L DI F     G L +P+LL+ D T S   NL+A E C    +  ++TSY+ F++ LI+S +DV+ L+  GI+ ++  SD EV +LF+K+ +D+V  P       +   + ++ +  W+   A + + Y     +PW + +F GA+I LL +  +++F++
Sbjct:  115 PHTVSLGPYHHGDEHLRPMDYHKWRAVNMVMKRTKQGIEMYIDAMKELEERARACY--EGPIGLSSNKFTQMLVLDGCFVLDLFRGAYEG-FSKLGYDRNDPVFAMRGSMHSIRRDMLMLENQLP--LMPTYMPSTK-------------IENSQENNNKFFHPIADKDKEELHCLDVFRRSVLQ-PSLKPE-PRLSRRW-SWKPVVADKRQQKLLHCVTELREAGIKFKRRKSDRLWDIQFKN---GCLEIPKLLIHDGTKSLLSNLIAFEQCH-IDSTKQITSYIIFVENLINSNEDVRYLQYCGIIEHWLESDSEVVDLFHKLCQDVVFDPIDSYLYPLCLGVDRFYSRKWSLFSAVILHKYQLNLRSPWAYFSFFGAVILLLLTFCESFFTV 485          

Query:   70 PRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFA--------QLDLFLLENQLPY----KLLKILIGSAKDSQIWEQSITDFIAHNLM----TNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQG--RYEKVIKDIHKYCNNPWTDALAQVYYT----YFSTPWTFLAFIGAIIGLLFSAIQAYFS 448
            P+ V+LGP+HH   + Q  E  K +   + +  +    +   D +    +  R CY+   V    +++   +L +DGC +L  ++ G+   F +L    +  +FA        Q D+ +LENQLP     +LL++  G+   + + E  +  FI   LM    T TE+   + V   +   H L+     LL            G+   S    +  ++   ++ EL+++G   K + T    DI F     G L +P LL+ D T S FLNL+A E C   ++  ++TSY+ FMD LIDS +D+  L   GI+ +  GS+ EVA++FN++ +++V D       +++ ++H+     ++  L  +  T    Y   PW +L+F  A+I L+ +  Q+YF+
Sbjct:  197 PQTVSLGPYHHGRQQTQSMECHKWRAVNMVLKRTNQGIEVFLDAMIELEEKARACYEGSIV--LSSNEFTEMLLLDGCFILELLQ-GVNEGFLKLGYDHNDPVFAVRGSMHSIQRDMIMLENQLPLFVLNRLLELQPGTQNQTGLVELVVRFFIP--LMPTAETLTENSPPRGVSNGE--LHCLDVFHRSLLFPRSS-------GKANYSRVADKHLQRVIPTVTELRDAGFKFKLNKTDRFWDIKFSN---GYLEIPGLLIHDGTKSLFLNLIAFEQCH-IESSNDITSYIIFMDNLIDSPEDISYLHHCGIIEHSLGSNSEVADMFNQLCQEVVFDTKDIYLSQLLIEVHRCYKQNYSRKLNSLKTTLILKYLDNPWAYLSFFAAVILLILTFSQSYFA 579          

Query:   64 FQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVS---GTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVL------CAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAK--DSQIWEQSITDFIAHNLM-TNTEHRKGKHVDGDKDYAHLLERLRDELL--TGEEMKIENSKIGRML---------------------------------------LSWGDS---RRHRKTFRSIKELKESGIHVKP-STTKNLKDIHFYCNFLGKLM-MPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLV--PDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFS 448
            ++  +EPR+V+LGP+HH     Q  E+ KL+F  +F+  +   G + + L   V    +D+R  Y  E + + D  KL  ++ +DGC +L        V    E + D +     +L   + DL LLENQ+P+ LL+ +   +K   S    + I  F  ++L  +NT   K + V+ +    HLL+ +R+  +    +E K  N  +  M+                                       L   DS   R H K   S ++L+  GI  K     + L DI       GKL+ +P L++DD   +  LN VA E    +     +TSY+ FM  L+ S  D   L   GIL NYFGS +EV+  F  + +D++   D+     + + ++KY ++ W    A   +T+F +PWT L+   A+  ++ + IQA+F+
Sbjct:   61 YKAAYEPRVVSLGPYHHGKKNLQMIEEHKLRFLKIFMDEAKRKGVDTNGLIKAVSVLEEDIRDSYS-ESLYS-DGKKLIEMMVLDGCFILMIFLVVAGVVSHSEIENDPIFAIPWILPAIRNDLILLENQVPFFLLQTIFDRSKIEKSSGLNEIIFHFFNYSLQKSNTFWLKHQKVEAN----HLLDLIRNIYMPDVPKEEKKSNHLLDCMMIRKICMPRESKQELDVMLKKGKQEVDISMLEEGIPKSDSLEEEDSTTGRHHLKMVLSARKLQLKGIKFKARKKAETLMDIRHK----GKLLQIPPLILDDFLIAVLLNCVAFEQYYSYCTKQHMTSYVAFMGCLLKSEADAMFLSEVGILENYFGSGDEVSRFFKVVGKDVLFDIDESYLAGIFEGVNKYTSSGWHVQWAGFKHTHFDSPWTALSSCAALTLVILTIIQAFFA 495          

Query:   67 CFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQID---DLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCA---VRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKIL-IGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYA--HLLERLRDELL--TGEEMKIENSKIGRMLLSWGDS-------RRHRKTFRSIKELKESGIHVKPSTTK--NLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALE-MCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTG-ILHNYFGSDEEVANLFNKMSRDLV--PDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
             ++P++V++GP+H+     Q  +Q K +   LF+  +     +    VKA +D    +RK Y  E    +D   L +++ +DGC +L     +   +E   D + +   LL   Q DL LLENQ+P+ +L+ L +GS    +I   S  + IA +   N   ++G + +  ++Y   HLL+ +R+  L  T E  K  +  + ++ L  G S        +      S K L+  GI  +   +K  ++ ++    N   KL +P+L  D   +S FLN VA E    D  N  E+T+Y+ FM  L+++ +DV  LR    I+ N+FGS+ EV+  F  +S+D+V   D      V K +++Y    +    A   +T+F +PWTFL+    +  +L + +Q+  ++
Sbjct:   62 AYKPKVVSIGPYHYGEKHLQMIQQHKPRLLQLFLDEAKKKDVEENVLVKAVVDLEDKIRKSYSEELKTGHD---LMFMMVLDGCFILMVFLIMSGNIELSEDPIFSIPWLLSSIQSDLLLLENQVPFFVLQTLYVGS----KIGVSSDLNRIAFHFFKNPIDKEGSYWEKHRNYKAKHLLDLIRETFLPNTSESDKASSPHV-QVQLHEGKSGNVPSVDSKAVPLILSAKRLRLQGIKFRLRRSKEDSILNVRLKKN---KLQIPQLRFDGFISSFFLNCVAFEQFYTDSSN--EITTYIVFMGCLLNNEEDVTFLRNDKLIIENHFGSNNEVSEFFKTISKDVVFEVDTSYLNNVFKGVNEYTKKWYNGLWAGFRHTHFESPWTFLSSCAVLFVILLTMLQSTVAI 455          

Query:   67 CFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQID---DLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCA---VRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKIL-IGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYA--HLLERLRDELL--TGEEMKIENSKIGRMLLSWGDS-------RRHRKTFRSIKELKESGIHVKPSTTK--NLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALE-MCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTG-ILHNYFGSDEEVANLFNKMSRDLV--PDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSL 449
             ++P++V++GP+H+     Q  +Q K +   LF+  +     +    VKA +D    +RK Y  E    +D   L +++ +DGC +L     +   +E   D + +   LL   Q DL LLENQ+P+ +L+ L +GS    +I   S  + IA +   N   ++G + +  ++Y   HLL+ +R+  L  T E  K  +  + ++ L  G S        +      S K L+  GI  +   +K  ++ ++    N   KL +P+L  D   +S FLN VA E    D  N  E+T+Y+ FM  L+++ +DV  LR    I+ N+FGS+ EV+  F  +S+D+V   D      V K +++Y    +    A   +T+F +PWTFL+    +  +L + +Q+  ++
Sbjct:   62 AYKPKVVSIGPYHYGEKHLQMIQQHKPRLLQLFLDEAKKKDVEENVLVKAVVDLEDKIRKSYSEELKTGHD---LMFMMVLDGCFILMVFLIMSGNIELSEDPIFSIPWLLSSIQSDLLLLENQVPFFVLQTLYVGS----KIGVSSDLNRIAFHFFKNPIDKEGSYWEKHRNYKAKHLLDLIRETFLPNTSESDKASSPHV-QVQLHEGKSGNVPSVDSKAVPLILSAKRLRLQGIKFRLRRSKEDSILNVRLKKN---KLQIPQLRFDGFISSFFLNCVAFEQFYTDSSN--EITTYIVFMGCLLNNEEDVTFLRNDKLIIENHFGSNNEVSEFFKTISKDVVFEVDTSYLNNVFKGVNEYTKKWYNGLWAGFRHTHFESPWTFLSSCAVLFVILLTMLQSTVAI 455          

Query:  273 TFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDL-VPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPW 426
            T  S+ +L ++G+  KP+   N+  + F  N  G+  +P + +D +T +   NLVA E   +       T Y   ++ +IDS +DV+ LR  G+L +   SD+E A ++N MS+ + +   G  +K I+D+++Y    W   + ++   Y    W
Sbjct:  344 TIPSVSDLHKAGVRFKPTAHGNISTVTFDSNS-GQFYLPVINLDINTETVLRNLVAYE-ATNTSGPLVFTRYTELINGIIDSEEDVRLLREQGVLVSRLKSDQEAAEMWNGMSKSVRLTKVGFLDKTIEDVNRYYTGRWKVKIGRLVEVYVYGSW 496          

Query:    1 MDTIIEMPAEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLPQNRNS 455
            MDTIIEMPAEPLN M +K +EFDSALHEV+NQ +  AQ  T PQ TKPLIQRVSP+L+NMKADFQ CFEPRLVALGP HH NPK QRAEQSKLKFAALFV+ + TNRDDLFDKVKA+I DLRKCY PED+ AYD++ LAW+LFVDGCAVLCAVRY                          ENQLPYKLLKILIGSAKD +IWE+SITDF+A NLMTN + +K KHV  +KDYAHLLERLRDELLTG+EMKI++S IGRMLLS GD+R+HRKTFRSIKELKESGIHVKPSTT NLKDI F CNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMD LID+ADDVKELRVTG+LHNY GSDEEVANLFNKMSRDLVPDQ RYEKVI+DIH+YCNNPWTDALAQ+YYTYFSTPWTFLAF+GAIIGLLFSAIQAYFSLPQNR+ 
Sbjct:    1 MDTIIEMPAEPLNFMVKKKREFDSALHEVRNQGK--AQLPTSPQITKPLIQRVSPVLINMKADFQKCFEPRLVALGPLHHGNPKLQRAEQSKLKFAALFVNENETNRDDLFDKVKAEIGDLRKCYNPEDIAAYDDEMLAWMLFVDGCAVLCAVRY--------------------------ENQLPYKLLKILIGSAKDPEIWEKSITDFVAENLMTNIK-QKSKHVADNKDYAHLLERLRDELLTGKEMKIDSSVIGRMLLSCGDNRKHRKTFRSIKELKESGIHVKPSTTNNLKDISFSCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDALIDTADDVKELRVTGMLHNYLGSDEEVANLFNKMSRDLVPDQTRYEKVIEDIHRYCNNPWTDALAQIYYTYFSTPWTFLAFVGAIIGLLFSAIQAYFSLPQNRSG 426          

Query:    1 MDTIIEMPAE---PLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPW 410
            MDTIIE+PAE   PLN ME+KMKEFDSALHEVQ Q++QQAQ STPPQTTKPLIQRVS LLL+ KADFQ CFEPRLVA GP HH NPKFQRAEQSKLKFAA FV VSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCA+L AVRYGMEGKFDEL TKADLL+FAQLDLFLLENQLPYKLLKILIGSAKD QIWEQ ITDFIA NLMTNTE+R+ KHVD DKDYAHLLERLRDELLTGEEM+I++S +GRMLLS G SR+HRK FRSIKELKESGIHVKPSTT NLKDI FYCNFLG LMMPRLLVDDSTA KFLNLVALEMC+DFKND+EVTSYLCFMD LI+SADDVKELR TG LHNY G +EEVA LF KMSR LVPD  RY  VI DIHKYCN+PW
Sbjct:    1 MDTIIEIPAEAAEPLNFMEQKMKEFDSALHEVQIQERQQAQRSTPPQTTKPLIQRVSFLLLDKKADFQKCFEPRLVAFGPLHHGNPKFQRAEQSKLKFAARFVRVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCALLYAVRYGMEGKFDELTTKADLLVFAQLDLFLLENQLPYKLLKILIGSAKDPQIWEQPITDFIAQNLMTNTEYRERKHVDDDKDYAHLLERLRDELLTGEEMRIDSSVMGRMLLSSGVSRKHRKMFRSIKELKESGIHVKPSTTNNLKDISFYCNFLGTLMMPRLLVDDSTACKFLNLVALEMCQDFKNDYEVTSYLCFMDALIESADDVKELRATGTLHNYLGKNEEVAELFKKMSRGLVPDHARYINVIDDIHKYCNSPW 413          

Query:    7 MPAEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPW 410
            MPAEPLN +EEKMKEFDSALHEVQNQ   +AQGSTPPQTTKPLIQRVSPLLL+  ADFQ CFEPRLVA GP HH NPKFQRAEQ K+KFAA FVHVSGT  DDLF+KVKAQIDDLRKCY PEDVEAYDNDKLAW+LFVDGCAVLC V   MEGKFDELNTKA LL+FAQLDLFLLENQLPYKLLKILIGSAKD +IWE+SITDF+A NLMTN E +K KHV  +KDYAHLLERLRD+LLTG+EMK EN+KIG +LLS G SR+HRKTFRSIKELKESGIHVKPSTT NLKDI FYCNF+GKL MPRLL DDSTASKFLNLVALEMC+DFKND EVTSYLCFMD LIDSADDVKELR TG+LHNY G +EEVA LF KMSR LVPDQ RYE VI DIHKYCNNPW
Sbjct:    1 MPAEPLNFLEEKMKEFDSALHEVQNQ---EAQGSTPPQTTKPLIQRVSPLLLDKMADFQKCFEPRLVAFGPLHHGNPKFQRAEQYKIKFAARFVHVSGTKHDDLFNKVKAQIDDLRKCYTPEDVEAYDNDKLAWMLFVDGCAVLCVVHCVMEGKFDELNTKAYLLVFAQLDLFLLENQLPYKLLKILIGSAKDPEIWEKSITDFVAENLMTNIE-QKSKHVADNKDYAHLLERLRDKLLTGKEMKTENTKIGGILLSCGGSRKHRKTFRSIKELKESGIHVKPSTTNNLKDISFYCNFMGKLTMPRLLADDSTASKFLNLVALEMCQDFKNDSEVTSYLCFMDALIDSADDVKELRDTGMLHNYLGKNEEVAELFKKMSRGLVPDQARYEMVINDIHKYCNNPW 400          

Query:    1 MDTIIEMPAEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPW 410
            MD+IIEMPAEPL+ MEEKMKEF SAL+EVQNQ+QQQAQGSTPPQTTKPLIQRVSPLLL+ KADFQ CFEPRLVA GP HH NPKFQRAEQ KLKFAA FVHVSGTN DDLF KVKAQIDDLRKCY PEDVEAYD+DKLAW+LFVDG AVLCAVRY MEGKFDELNT+  LL+FAQLDLFLLENQLPYKLLKILIGSAKD QIWEQ ITDFIA NLMTNTE+R+ KHVD DKDYAHLLERLRDELLTGEEM+I++S +GRMLLS G SR+HRK FRSIKELKESGIHVKPSTT NLKDI FYCNFLG LMMPRLLVDDSTASKFLNLVALEMC+DFKND EVTSYLCFMD LI+SADDVKELR TG+LHNY G +EEVA LF  MS  LVPDQ RY +VI DIHKYCN+PW
Sbjct:    1 MDSIIEMPAEPLDFMEEKMKEFYSALYEVQNQEQQQAQGSTPPQTTKPLIQRVSPLLLDKKADFQKCFEPRLVAFGPLHHGNPKFQRAEQYKLKFAARFVHVSGTNCDDLFKKVKAQIDDLRKCYTPEDVEAYDDDKLAWMLFVDGSAVLCAVRYVMEGKFDELNTRTYLLVFAQLDLFLLENQLPYKLLKILIGSAKDPQIWEQPITDFIAQNLMTNTEYRERKHVDDDKDYAHLLERLRDELLTGEEMRIDSSVMGRMLLSSGVSRKHRKMFRSIKELKESGIHVKPSTTNNLKDISFYCNFLGTLMMPRLLVDDSTASKFLNLVALEMCQDFKNDSEVTSYLCFMDALIESADDVKELRDTGMLHNYLGKNEEVAELFKNMSGGLVPDQTRYIEVIDDIHKYCNSPW 410          

Query:    7 MPAEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPW 410
            MPAEPL+ MEEKMKEF SAL+EVQNQ+QQQAQGSTPPQTTKPLIQRVSPLLL+ KADFQ CFEPRLVA GP HH NPKFQRAEQ KLKFAA FVHVSGTN DDLF KVKAQIDDLRKCY PEDVEAYD+DKLAW+LFVDG AVLCAVRY MEG FDELNT+  LL+FAQLDLFLLENQLPYKLLKILIGSAKD  +WEQSITDFIAHNLMTN  H+K K V  DKDYAHLLERLRDELLTG+EMKI++S +GRMLLS G SR+HRKTFRSIKELKESGIHVKPSTT NLKDI FYCNFLG LMMPRLLVDDSTASKFLNLVALEMC+DFKND EVTSYLCFMD LI+SADDVKELR TG+LHNY G +EEVA LF  MS  LVPDQ RY +VI DIHKYCN+PW
Sbjct:    1 MPAEPLDFMEEKMKEFYSALYEVQNQEQQQAQGSTPPQTTKPLIQRVSPLLLDKKADFQKCFEPRLVAFGPLHHGNPKFQRAEQYKLKFAARFVHVSGTNCDDLFKKVKAQIDDLRKCYTPEDVEAYDDDKLAWMLFVDGSAVLCAVRYVMEGMFDELNTRTYLLVFAQLDLFLLENQLPYKLLKILIGSAKDPPVWEQSITDFIAHNLMTNI-HQKRKQVVDDKDYAHLLERLRDELLTGKEMKIDSSVMGRMLLSSGVSRKHRKTFRSIKELKESGIHVKPSTTNNLKDISFYCNFLGTLMMPRLLVDDSTASKFLNLVALEMCQDFKNDSEVTSYLCFMDALIESADDVKELRDTGMLHNYLGKNEEVAELFKNMSGGLVPDQTRYIEVIDDIHKYCNSPW 403          

Query:    7 MP-AEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSG-TNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLPQNRNS 455
            MP A P + +EEK   F SAL+EVQNQ   Q +                         FQ  FEPRLVALGP HH  P+F  +EQ+KLKFAA F HV+G T+  +LF +V+A+I DLRKCY PED+ AYD+++LAW+LFVDGCAVLCAVRY +EGKFDELNTKADLL+FAQ+DLFLLENQLPYKLLKILIGSAKD +IWEQSIT+FIA NLMTN E ++ KHVD +KDYAHLLER RD++LTG+EMK ++S +GR LLSWG S +HR+TFR +KELKESGIHVKPSTT NLK+I FYCN+LGKLM+PRLLVDDS ASKFLNL+ALEMC DFKN FEVTSYLCFMD+LI SADDVKELRV+G+ HNY GSDEEVA LFNKMSRDLVPDQ RY KV +DIHKY  NPWT ALA+ YYT+FS PWTFLAF+GAI+GLLFSAIQAYFSLPQN++S
Sbjct:    1 MPEAVPWDFIEEKRDAFKSALYEVQNQGPLQGR-------------------------FQEMFEPRLVALGPLHHGKPEFMCSEQAKLKFAARFAHVNGYTDDQELFYRVRAEIGDLRKCYNPEDIAAYDDERLAWMLFVDGCAVLCAVRYVVEGKFDELNTKADLLVFAQVDLFLLENQLPYKLLKILIGSAKDPKIWEQSITEFIAQNLMTNIE-QESKHVDDNKDYAHLLERFRDQILTGDEMKRDSSVMGRKLLSWGGSGKHRRTFRGLKELKESGIHVKPSTTNNLKNISFYCNYLGKLMIPRLLVDDSMASKFLNLIALEMCPDFKNKFEVTSYLCFMDSLIGSADDVKELRVSGVQHNYLGSDEEVAELFNKMSRDLVPDQKRYFKVTEDIHKYRTNPWTAALAKAYYTHFSRPWTFLAFMGAIMGLLFSAIQAYFSLPQNKSS 425          

Query:   24 SALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNT-EHRKGKHVDGD--KDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLPQNR 453
            SAL E Q Q+      S   Q  KPLIQRV P+L+ +K DF+  FEPRLVALGP HH  P+F++AE +K K AALF + + T  + LF+K+ A+I DL++CY PED++ YD++KLAW+ FVDGCAVL AV YG++GKF +LNTKADLL+FAQLDLFLLENQLPY++L ILIGS K+ Q+WEQSIT+F+ +NL+TN  + +K +H D +  ++Y HLLERLR +LLTG++ +  +S IGR+LLS GD R+HRKTFRS+KELKESGI V PS T NLK+I FYCNFLG L MPR+LVDDSTASKFLNLVALEMCRDF+NDF VTSYL F+D+LID+A+DVKE+RVTG+LHNY GSDEEVA+LFNK+SRDLVPDQ  Y+ V  +IHKYCNNP T A+AQ YYT+FS+PWTFL F+GAIIGLLFSAIQAY+S P N+
Sbjct:   33 SALREAQKQE------SDSYQRAKPLIQRVPPVLIGIKEDFKKYFEPRLVALGPLHHGKPQFEQAEHTKRKLAALFANENETTDEVLFNKIMAEIRDLKQCYNPEDIKDYDDEKLAWMFFVDGCAVLYAVHYGLQGKFKKLNTKADLLVFAQLDLFLLENQLPYRVLNILIGSTKEPQMWEQSITEFVGNNLITNIPDGKKSQHTDEEEKQEYTHLLERLRTKLLTGKKEESSSSMIGRLLLSCGDIRKHRKTFRSVKELKESGIGVGPSETNNLKNISFYCNFLGSLKMPRILVDDSTASKFLNLVALEMCRDFENDFAVTSYLYFLDSLIDTAEDVKEMRVTGMLHNYLGSDEEVADLFNKLSRDLVPDQAMYKDVTDNIHKYCNNPCTTAMAQAYYTHFSSPWTFLGFLGAIIGLLFSAIQAYYSFPDNK 459          

Query:   33 KQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNT-EHRKGKHVDGD--KDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLPQNRNS 455
            ++ Q Q S   Q  KPLIQRV P+L+ +K DF+  FEPRLVALGP HH  P+F+RAE +K K A LF + + T  + LF+K+ A+I DL++CY PED++ YD++KLAW+ FVDGCAVL AV YG++G F +LN KADLL+FAQLDLFLLENQLPY++L ILIGS KD Q+WEQSIT F+ +NL+TN  + +K +H D +  ++Y HLLERLR + LTG++ +  +S IGR+LLS GD+R+HRKTFRS+KELKESGI V PS T NLK+I FYCNFLG L MPR+LVDDSTASKFLNLVALEMCRDF+NDF VTSYL F+D+LID+A+DVKE+RVTG+LHNY GSDEEVA+LFNK+SRDLVPDQ  Y+ V  +IHKYCNNPWT A+AQ YYT+FS+PWTFL  + A++GLLFSAIQAY++ P ++ S
Sbjct:   36 REAQKQESDSSQRAKPLIQRVPPVLIGIKEDFKKYFEPRLVALGPLHHGKPQFERAEHTKRKLAGLFANENETTDEVLFNKIMAEIKDLKQCYNPEDIKDYDDEKLAWMFFVDGCAVLFAVHYGLQGDFKKLNIKADLLVFAQLDLFLLENQLPYRVLNILIGSTKDPQMWEQSITKFVGNNLITNIPDGKKSQHTDEEEKQEYTHLLERLRTKHLTGKKEESSSSMIGRLLLSCGDNRKHRKTFRSVKELKESGIGVGPSETNNLKNISFYCNFLGSLKMPRILVDDSTASKFLNLVALEMCRDFENDFAVTSYLYFLDSLIDTAEDVKEMRVTGMLHNYLGSDEEVADLFNKLSRDLVPDQAMYKDVTDNIHKYCNNPWTTAMAQAYYTHFSSPWTFLGLLAALLGLLFSAIQAYYAFPNHKRS 461          

Query:   57 LLNMKADFQICFEPRLVALGPFHHDNPK--FQRAEQSKLKFAALFVHVSG-TNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLP 450
            L   +  FQ  FEPRLVAL P HH  P      + + KL+FAA F HV+G T+  +LF +V+A+I DLRKCY  ED+ AYD++KLAW+LFVDGCAVLCAV Y +E                       EN+LPYKLLKILI SAKD QIWEQSITDFIA NLMTNTEHRK KHVD DKDYAHLLERLRDELLTGEEMKI+NSKIGRMLLS GDSR+HRKTFRSIKELKESGIHVKPSTT NLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMD+LI SADDVKELRV+G+LHNY GSDEEVA LFNKMS DLVPDQ RY KV +DIHKY  NPWT ALA+ YYT+FS PWTFLAF        FSAIQAYFSLP
Sbjct:   15 LTQHEGRFQEMFEPRLVALSPLHHGKPSSCAPSSPRPKLRFAARFAHVNGYTDDQELFYRVRAEIGDLRKCYNREDIAAYDDEKLAWMLFVDGCAVLCAVSYVVE-----------------------ENRLPYKLLKILICSAKDPQIWEQSITDFIAQNLMTNTEHRKRKHVDDDKDYAHLLERLRDELLTGEEMKIDNSKIGRMLLSCGDSRKHRKTFRSIKELKESGIHVKPSTTNNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDSLIGSADDVKELRVSGVLHNYLGSDEEVAELFNKMSSDLVPDQKRYFKVTEDIHKYRTNPWTAALAKAYYTHFSRPWTFLAFQA-----YFSAIQAYFSLP 383          

Query:   19 MKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHK----YCNNPWTDALAQV 417
            MKEF SAL+EVQNQ+QQQAQGSTPPQTTKPLIQRVSPLLL+ KADFQ CFEPRLVA GP HH NPKFQRAEQ KLKFAA FVHVSGTN DDLF KVKAQIDDLRKCY PEDVEAYD+DKLAW+LFVDGCAVLCAVRY MEG FDELNT+  LL+FAQLDLFL ENQLPYKLLKILIGSAKD                                       RLRDELLTG++MKI++S +GRMLLS G SR+HRK FRSIKELKESGIHVKPSTT NLKDI FYCNFLG LMMPRLL        FLNLVALEMC+DFKND EVTSYLCFMD LI+SADDVKELR TG+LHNY G +EEVA LF KMS  LVPDQ RY +VI DIH     +   PW  ++  +
Sbjct:    1 MKEFYSALYEVQNQEQQQAQGSTPPQTTKPLIQRVSPLLLDKKADFQKCFEPRLVAFGPLHHGNPKFQRAEQYKLKFAARFVHVSGTNCDDLFKKVKAQIDDLRKCYTPEDVEAYDDDKLAWMLFVDGCAVLCAVRYVMEGMFDELNTRTYLLVFAQLDLFLQENQLPYKLLKILIGSAKDP-------------------------------------PRLRDELLTGKKMKIDSSVMGRMLLSSGVSRKHRKMFRSIKELKESGIHVKPSTTNNLKDISFYCNFLGTLMMPRLL--------FLNLVALEMCQDFKNDSEVTSYLCFMDALIESADDVKELRDTGMLHNYLGKNEEVAELFKKMSGGLVPDQTRYIEVIDDIHNTATIHGRMPWLKSITPI 358          

Query:    1 MDTIIEMPAEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLPQNRNS 455
            MDTIIEMPAEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLPQNRNS
Sbjct:    1 MDTIIEMPAEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLPQNRNS 455          

Query:    1 MDTIIEMPAEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLPQNRNS 455
            MDTIIEMPAEPLN ME+K +EFDSALHEV+NQ +  AQ  T PQ TKPLIQRVSP+L+NMKADFQ CFEPRLVALGP HH NPK QRAEQSKLKFAALFV+ + TNRDDLFDKVKA+I DLRKCY PED+ AYD++ LAW+LFVDGCAVLCAVRY                          ENQLPYKLLKILIGSAKD +IWE+SITDF+A NLMTN + +K KHV  +KDYAHLLERLRDELLTG+EMKI++S IGRMLLS GD+R+HRKTFRSIKELKESGIHVKPSTT NLKDI F CNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLID+ADDVKELRVTG+LHNY GSDEEVANLFNKMSRDLVPDQ RYEKVI+DIH+YCNNPWTDALAQ+YYTYFSTPWTFLAF+GAIIGLLFSAIQAYFSLPQNR+ 
Sbjct:    1 MDTIIEMPAEPLNFMEKKTREFDSALHEVRNQGK--AQRPTSPQITKPLIQRVSPVLINMKADFQKCFEPRLVALGPLHHGNPKLQRAEQSKLKFAALFVNENETNRDDLFDKVKAEIGDLRKCYNPEDIAAYDDEMLAWMLFVDGCAVLCAVRY--------------------------ENQLPYKLLKILIGSAKDPEIWEKSITDFVAENLMTNIK-QKSKHVADNKDYAHLLERLRDELLTGKEMKIDSSVIGRMLLSCGDNRKHRKTFRSIKELKESGIHVKPSTTNNLKDISFSCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDTADDVKELRVTGMLHNYLGSDEEVANLFNKMSRDLVPDQTRYEKVIEDIHRYCNNPWTDALAQIYYTYFSTPWTFLAFVGAIIGLLFSAIQAYFSLPQNRSG 426          

Query:    1 MDTIIEMPAEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLPQNRNS 455
            MDTIIEMPAEPLN M +K +EFDSALHEV+NQ +  AQ  T PQ TKPLIQRVSP+L+NMKADFQ CFEPRLVALGP HH NPK QRAEQSKLKFAALFV+ + TNRDDLFDKVKA+I DLRKCY PED+ AYD++ LAW+LFVDGCAVLCAVRY                          ENQLPYKLLKILIGSAKD +IWE+SITDF+A NLMTN + +K KHV  +KDYAHLLERLRDELLTG+EMKI++S IGRMLLS GD+R+HRKTFRSIKELKESGIHVKPSTT NLKDI F CNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMD LID+ADDVKELRVTG+LHNY GSDEEVANLFNKMSRDLVPDQ RYEKVI+DIH+YCNNPWTDALAQ+YYTYFSTPWTFLAF+GAIIGLLFSAIQAYFSLPQNR+ 
Sbjct:    1 MDTIIEMPAEPLNFMVKKKREFDSALHEVRNQGK--AQLPTSPQITKPLIQRVSPVLINMKADFQKCFEPRLVALGPLHHGNPKLQRAEQSKLKFAALFVNENETNRDDLFDKVKAEIGDLRKCYNPEDIAAYDDEMLAWMLFVDGCAVLCAVRY--------------------------ENQLPYKLLKILIGSAKDPEIWEKSITDFVAENLMTNIK-QKSKHVADNKDYAHLLERLRDELLTGKEMKIDSSVIGRMLLSCGDNRKHRKTFRSIKELKESGIHVKPSTTNNLKDISFSCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDALIDTADDVKELRVTGMLHNYLGSDEEVANLFNKMSRDLVPDQTRYEKVIEDIHRYCNNPWTDALAQIYYTYFSTPWTFLAFVGAIIGLLFSAIQAYFSLPQNRSG 426          

Query:    1 MDTIIEMPAE---PLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPW 410
            MDTIIE+PAE   PLN ME+KMKEFDSALHEVQ Q++QQAQ STPPQTTKPLIQRVS LLL+ KADFQ CFEPRLVA GP HH NPKFQRAEQSKLKFAA FV VSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCA+L AVRYGMEGKFDEL TKADLL+FAQLDLFLLENQLPYKLLKILIGSAKD QIWEQ ITDFIA NLMTNTE+R+ KHVD DKDYAHLLERLRDELLTGEEM+I++S +GRMLLS G SR+HRK FRSIKELKESGIHVKPSTT NLKDI FYCNFLG LMMPRLLVDDSTA KFLNLVALEMC+DFKND+EVTSYLCFMD LI+SADDVKELR TG LHNY G +EEVA LF KMSR LVPD  RY  VI DIHKYCN+PW
Sbjct:    1 MDTIIEIPAEAAEPLNFMEQKMKEFDSALHEVQIQERQQAQRSTPPQTTKPLIQRVSFLLLDKKADFQKCFEPRLVAFGPLHHGNPKFQRAEQSKLKFAARFVRVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCALLYAVRYGMEGKFDELTTKADLLVFAQLDLFLLENQLPYKLLKILIGSAKDPQIWEQPITDFIAQNLMTNTEYRERKHVDDDKDYAHLLERLRDELLTGEEMRIDSSVMGRMLLSSGVSRKHRKMFRSIKELKESGIHVKPSTTNNLKDISFYCNFLGTLMMPRLLVDDSTACKFLNLVALEMCQDFKNDYEVTSYLCFMDALIESADDVKELRATGTLHNYLGKNEEVAELFKKMSRGLVPDHARYINVIDDIHKYCNSPW 413          

Query:    7 MPAEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPW 410
            MPAEPLN +EEKMKEFDSALHEVQNQ   +AQGSTPPQTTKPLIQRVSPLLL+  ADFQ CFEPRLVA GP HH NPKFQRAEQ K+KFAA FVHVSGT  DDLF+KVKAQIDDLRKCY PEDVEAYDNDKLAW+LFVDGCAVLC V   MEGKFDELNTKA LL+FAQLDLFLLENQLPYKLLKILIGSAKD +IWE+SITDF+A NLMTN E +K KHV  +KDYAHLLERLRD+LLTG+EMK EN+KIG +LLS G SR+HRKTFRSIKELKESGIHVKPSTT NLKDI FYCNF+GKL MPRLL DDSTASKFLNLVALEMC+DFKND EVTSYLCFMD LIDSADDVKELR TG+LHNY G +EEVA LF KMSR LVPDQ RYE VI DIHKYCNNPW
Sbjct:    1 MPAEPLNFLEEKMKEFDSALHEVQNQ---EAQGSTPPQTTKPLIQRVSPLLLDKMADFQKCFEPRLVAFGPLHHGNPKFQRAEQYKIKFAARFVHVSGTKHDDLFNKVKAQIDDLRKCYTPEDVEAYDNDKLAWMLFVDGCAVLCVVHCVMEGKFDELNTKAYLLVFAQLDLFLLENQLPYKLLKILIGSAKDPEIWEKSITDFVAENLMTNIE-QKSKHVADNKDYAHLLERLRDKLLTGKEMKTENTKIGGILLSCGGSRKHRKTFRSIKELKESGIHVKPSTTNNLKDISFYCNFMGKLTMPRLLADDSTASKFLNLVALEMCQDFKNDSEVTSYLCFMDALIDSADDVKELRDTGMLHNYLGKNEEVAELFKKMSRGLVPDQARYEMVINDIHKYCNNPW 400          

Query:    3 TIIEMP-AEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSG-TNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLPQNRNS 455
            TII+MP A P + +EEK   F SAL+EVQNQ     QGS   Q  KPLIQRVSPLLLN KADF+ CFEPRLVA GP HH  P+F R+EQ KLKFAA F   +G T+  +LF +V A+I DLRKCY PED+ AY++++LAW+LFVDGCAVLCAVRY +EGKFDELNTKADLL+FAQLDLFLLENQLPYKLLKILIGSAKD ++WEQSIT+FIA NLMTN E ++ KHVD +KDYAHLLER RD+LLTG++MK ++S +GR LLSWGDSR+HR+TFR +KELKESGIHVKPSTT NLK+I FYCN+LGKLM+PRLLVDDS ASKFLNLVALEMC DFKN FEVTSYLCFMD+LI SADDVKELRV+G+L NY GSDEEV  LFNKMSRDLVPDQ RY KV +DIHKY  NPWT ALA+ YYT+F  PWTFLAF+GAI+GLLFSAIQAYFSLPQN++S
Sbjct:   11 TIIQMPEAVPWDFIEEKRDAFKSALYEVQNQGP--LQGSW--QGAKPLIQRVSPLLLNTKADFKKCFEPRLVAFGPLHHGKPEFMRSEQVKLKFAARFALDNGYTDDQELFYRVMAEIGDLRKCYNPEDIAAYNDERLAWMLFVDGCAVLCAVRYVVEGKFDELNTKADLLVFAQLDLFLLENQLPYKLLKILIGSAKDPKVWEQSITEFIAQNLMTNIE-QESKHVDDNKDYAHLLERFRDQLLTGDKMKRDSSVMGRKLLSWGDSRKHRRTFRGVKELKESGIHVKPSTTNNLKNISFYCNYLGKLMIPRLLVDDSMASKFLNLVALEMCPDFKNKFEVTSYLCFMDSLIGSADDVKELRVSGVLLNYLGSDEEVVELFNKMSRDLVPDQKRYFKVTEDIHKYRTNPWTAALAKAYYTHFERPWTFLAFMGAIMGLLFSAIQAYFSLPQNKSS 460          

Query:    1 MDTIIEMPAEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPW 410
            MD+IIEMPAEPL+ MEEKMKEF SAL+EVQNQ+QQQAQGSTPPQTTKPLIQRVSPLLL+ KADFQ CFEPRLVA GP HH NPKFQRAEQ KLKFAA FVHVSGTN DDLF KVKAQIDDLRKCY PEDVEAYD+DKLAW+LFVDG AVLCAVRY MEGKFDELNT+  LL+FAQLDLFLLENQLPYKLLKILIGSAKD QIWEQ ITDFIA NLMTNTE+R+ KHVD DKDYAHLLERLRDELLTGEEM+I++S +GRMLLS G SR+HRK FRSIKELKESGIHVKPSTT NLKDI FYCNFLG LMMPRLLVDDSTASKFLNLVALEMC+DFKND EVTSYLCFMD LI+SADDVKELR TG+LHNY G +EEVA LF  MS  LVPDQ RY +VI DIHKYCN+PW
Sbjct:    1 MDSIIEMPAEPLDFMEEKMKEFYSALYEVQNQEQQQAQGSTPPQTTKPLIQRVSPLLLDKKADFQKCFEPRLVAFGPLHHGNPKFQRAEQYKLKFAARFVHVSGTNCDDLFKKVKAQIDDLRKCYTPEDVEAYDDDKLAWMLFVDGSAVLCAVRYVMEGKFDELNTRTYLLVFAQLDLFLLENQLPYKLLKILIGSAKDPQIWEQPITDFIAQNLMTNTEYRERKHVDDDKDYAHLLERLRDELLTGEEMRIDSSVMGRMLLSSGVSRKHRKMFRSIKELKESGIHVKPSTTNNLKDISFYCNFLGTLMMPRLLVDDSTASKFLNLVALEMCQDFKNDSEVTSYLCFMDALIESADDVKELRDTGMLHNYLGKNEEVAELFKNMSGGLVPDQTRYIEVIDDIHKYCNSPW 410          

Query:    7 MPAEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSGTNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPW 410
            MPAEPL+ MEEKMKEF SAL+EVQNQ+QQQAQGSTPPQTTKPLIQRVSPLLL+ KADFQ CFEPRLVA GP HH NPKFQRAEQ KLKFAA FVHVSGTN DDLF KVKAQIDDLRKCY PEDVEAYD+DKLAW+LFVDG AVLCAVRY MEG FDELNT+  LL+FAQLDLFLLENQLPYKLLKILIGSAKD  +WEQSITDFIAHNLMTN  H+K K V  DKDYAHLLERLRDELLTG+EMKI++S +GRMLLS G SR+HRKTFRSIKELKESGIHVKPSTT NLKDI FYCNFLG LMMPRLLVDDSTASKFLNLVALEMC+DFKND EVTSYLCFMD LI+SADDVKELR TG+LHNY G +EEVA LF  MS  LVPDQ RY +VI DIHKYCN+PW
Sbjct:    1 MPAEPLDFMEEKMKEFYSALYEVQNQEQQQAQGSTPPQTTKPLIQRVSPLLLDKKADFQKCFEPRLVAFGPLHHGNPKFQRAEQYKLKFAARFVHVSGTNCDDLFKKVKAQIDDLRKCYTPEDVEAYDDDKLAWMLFVDGSAVLCAVRYVMEGMFDELNTRTYLLVFAQLDLFLLENQLPYKLLKILIGSAKDPPVWEQSITDFIAHNLMTNI-HQKRKQVVDDKDYAHLLERLRDELLTGKEMKIDSSVMGRMLLSSGVSRKHRKTFRSIKELKESGIHVKPSTTNNLKDISFYCNFLGTLMMPRLLVDDSTASKFLNLVALEMCQDFKNDSEVTSYLCFMDALIESADDVKELRDTGMLHNYLGKNEEVAELFKNMSGGLVPDQTRYIEVIDDIHKYCNSPW 403          

Query:    7 MP-AEPLNSMEEKMKEFDSALHEVQNQKQQQAQGSTPPQTTKPLIQRVSPLLLNMKADFQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSG-TNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLPQNRNS 455
            MP A P + +EEK   F SAL+EVQNQ   Q +                         FQ  FEPRLVALGP HH  P+F  +EQ+KLKFAA F HV+G T+  +LF +V+A+I DLRKCY PED+ AYD+++LAW+LFVDGCAVLCAVRY +EGKFDELNTKADLL+FAQ+DLFLLENQLPYKLLKILIGSAKD +IWEQSIT+FIA NLMTN E ++ KHVD +KDYAHLLER RD++LTG+EMK ++S +GR LLSWG S +HR+TFR +KELKESGIHVKPSTT NLK+I FYCN+LGKLM+PRLLVDDS ASKFLNL+ALEMC DFKN FEVTSYLCFMD+LI SADDVKELRV+G+ HNY GSDEEVA LFNKMSRDLVPDQ RY KV +DIHKY  NPWT ALA+ YYT+FS PWTFLAF+GAI+GLLFSAIQAYFSLPQN++S
Sbjct:    1 MPEAVPWDFIEEKRDAFKSALYEVQNQGPLQGR-------------------------FQEMFEPRLVALGPLHHGKPEFMCSEQAKLKFAARFAHVNGYTDDQELFYRVRAEIGDLRKCYNPEDIAAYDDERLAWMLFVDGCAVLCAVRYVVEGKFDELNTKADLLVFAQVDLFLLENQLPYKLLKILIGSAKDPKIWEQSITEFIAQNLMTNIE-QESKHVDDNKDYAHLLERFRDQILTGDEMKRDSSVMGRKLLSWGGSGKHRRTFRGLKELKESGIHVKPSTTNNLKNISFYCNYLGKLMIPRLLVDDSMASKFLNLIALEMCPDFKNKFEVTSYLCFMDSLIGSADDVKELRVSGVQHNYLGSDEEVAELFNKMSRDLVPDQKRYFKVTEDIHKYRTNPWTAALAKAYYTHFSRPWTFLAFMGAIMGLLFSAIQAYFSLPQNKSS 425          

Query:   64 FQICFEPRLVALGPFHHDNPKFQRAEQSKLKFAALFVHVSG-TNRDDLFDKVKAQIDDLRKCYKPEDVEAYDNDKLAWVLFVDGCAVLCAVRYGMEGKFDELNTKADLLIFAQLDLFLLENQLPYKLLKILIGSAKDSQIWEQSITDFIAHNLMTNTEHRKGKHVDGDKDYAHLLERLRDELLTGEEMKIENSKIGRMLLSWGDSRRHRKTFRSIKELKESGIHVKPSTTKNLKDIHFYCNFLGKLMMPRLLVDDSTASKFLNLVALEMCRDFKNDFEVTSYLCFMDTLIDSADDVKELRVTGILHNYFGSDEEVANLFNKMSRDLVPDQGRYEKVIKDIHKYCNNPWTDALAQVYYTYFSTPWTFLAFIGAIIGLLFSAIQAYFSLPQNRNS 455
            FQ  FEPRLVALGP HH  P+F  +EQ+KLKFAA F HV+G T+  +LF +V+A+I DLRKCY PED+ AYD+++LAW+LFVDGCAVLCAVRY +EGKFDELNTKADLL+FAQ+DLFLLENQLPYKLLKILIGSAKD +IWEQSIT+FIA NLMTN E ++ KHVD +KDYAHLLER RD++LTG+EMK ++S +GR LLSWG S +HR+TFR +KELKESGIHVKPSTT NLK+I FYCN+LGKLM+PRLLVDDS ASKFLNL+ALEMC DFKN FEVTSYLCFMD+LI SADDVKELRV+G+ HNY GSDEEVA LFNKMSRDLVPDQ RY KV +DIHKY  NPWT ALA+ YYT+FS PWTFLAF+GAI+GLLFSAIQAYFSLPQN++S
Sbjct:   22 FQEMFEPRLVALGPLHHGKPEFMCSEQAKLKFAARFAHVNGYTDDQELFYRVRAEIGDLRKCYNPEDIAAYDDERLAWMLFVDGCAVLCAVRYVVEGKFDELNTKADLLVFAQVDLFLLENQLPYKLLKILIGSAKDPKIWEQSITEFIAQNLMTNIE-QESKHVDDNKDYAHLLERFRDQILTGDEMKRDSSVMGRKLLSWGGSGKHRRTFRGLKELKESGIHVKPSTTNNLKNISFYCNYLGKLMIPRLLVDDSMASKFLNLIALEMCPDFKNKFEVTSYLCFMDSLIGSADDVKELRVSGVQHNYLGSDEEVAELFNKMSRDLVPDQKRYFKVTEDIHKYRTNPWTAALAKAYYTHFSRPWTFLAFMGAIMGLLFSAIQAYFSLPQNKSS 413