g.barbadense_cottongen_reftransV1_0097164, g.barbadense_cottongen_reftransV1_0097164 (contig) Gossypium barbadense

Query:  254 ISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYIPGTSRSNRKPXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYL-NETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIINSSRLPALM-LVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLR 1576
            I + D PGGS+AFE AAKFCYG+  D+S+  +  LRCAAE+LEMT+E+S +NL+ + E +L++   KSL +SI  L   E ++ +AE + +V R ID+IA    +   + F  P +      +    Q               ++   V+ W EDL +L +  F+R++  +  R      +   LM YA+K + G     +           E E+R +LETI+S LP EK   S S     L  LLR A  L  + + +  LE ++G QL QA LDDLLIPSYS+  + +++D D ++RIL  +L    E    G+   N G +        L   M  VGKL++ Y++EIASD N+  +KF  LA  +P+Q+R  +DG+YRAVD+YLKAHP + + ER+K+C ++DCQKL+ EAC HAAQN+RLP++ +VQVL++EQ +LR
Sbjct:   68 IKIPDIPGGSEAFELAAKFCYGINFDMSTENIAMLRCAAEYLEMTEEHSVENLVVRAEAYLNEVALKSLSSSITVLHKSEKLLPIAERVKLVSRCIDAIAYM--TCQESHFCSPSSSNSGNNEVVVQQQ--------------SKQPVVDWWAEDLTVLRIDSFQRVLIAMMARGFKQYGLGPVLMLYAQKSLRGLEIFGK--GMKKIEPKQEHEKRVILETIVSLLPREKNAMSVS----FLSMLLRAAIFLETTVACRLDLENRMGLQLGQAVLDDLLIPSYSFTGDHSMFDTDTVQRILMNYL----EFEVEGVRLSNNGVD--------LAGDMERVGKLLENYMAEIASDRNVSLQKFIGLAELIPEQSRVTEDGMYRAVDIYLKAHPNMSDVERKKVCSLMDCQKLSREACAHAAQNDRLPVQTIVQVLYYEQQRLR 476          

Query:  260 LQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGA---------------SAQALWN--------GIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYIPGTSR---------------------------------SNRKPXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYS-YLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIIN------SSRLP-----------------ALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETAPMNAGRLSGTXXXXXXXXXXXXXXXXXXVAMSRGEQGSTTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIQKIEKGNP 1867
            + D PGG+ +FE AA+F YG+ +DL+++ +  LRCAAE+LEMT+E  E NLI KTE FLS  V  S + SI  LKSCE++   AE+L IV R  +SIA +A + +P    W        + GA               +A   WN          E+   R+A+      + WFED+++L +  F R+++ +K + +  ++I + +  YA K++PG ++                                    K     A +    EQR ++E+IIS  P ++     S +   L  LLR A +L A+ +    LEK++G QLEQA L DLLIPSY     +T YDVD ++R++ +FL  ++E+    + A + G  D          S R+P                 A   V +L+D YLSE++ D NL   KF  LA SLP+ AR  DDGLYRAVD YLKAHP + E ER+++C V+DCQKL+ +AC HAAQNERLPLR VVQVLF EQ++    I+  L ++  A  ++    G          ++Q  +    +   G      W AA ++   L+ +++SM+ +  +L+ E   ++K +     G P
Sbjct:  102 MGDLPGGAGSFELAARFSYGMAVDLTAANISGLRCAAEYLEMTEEMEEGNLIFKTEAFLSYVVLSSWRDSIAVLKSCEALSPWAENLQIVRRCSESIAWKACA-NPRGVRWAYTGAGAGSGGARGGPAAIRGGGGSGGTASPRWNVGGGGGGESKESSPSRQAV---PPADWWFEDVSVLRIDHFVRVVTAIKVKGMRFDLIGAAITHYASKWLPGLTKDAPLGATHDEPWAQASAAGVGGGGLHMMIISGAGGGKDDVLAACSAPSREQRMVVESIISITPPQR----DSVSCGFLLRLLRLAIMLRAAPALVTELEKRVGMQLEQAALADLLIPSYGGRAADTAYDVDLVQRLVEHFL--VQEQTEMAV-ASSPGRGDPPPPPQPEYYSGRMPPSSAAAASASASTGGLNAKARVARLLDSYLSEVSRDRNLSLTKFQVLAESLPESARACDDGLYRAVDSYLKAHPTLTEHERKRLCRVMDCQKLSFDACMHAAQNERLPLRVVVQVLFTEQVK----ISNALASSSAALRSSSSAPGADAAPAMPTTRRQLLDGTPQSFQEG------WAAAKKDINTLKFELESMKAKYLELQHEMDALQKQVDGRGGGAP 696          

Query:  254 ISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYIPGTSRSNRKPXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNII--------NSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETA-------PMNAGRLSGTXXXXXXXXXXXXXXXXXXVAMSRGEQGSTTWRAAV-RENQVLRLDMDSMRTRVHQLERECSTMKK 1837
            ++L   PGGS++FE AAKFCYGV +  +SS +  LRC A +LEMT++ SE NL ++TE +L  S+F  +  SI  L SCE ++ +AE + +V RL+++IA+ A                 E   +    L      G+   A       + W   L +L L  F+R++S +K + L+ ++I   LM YA+K +       R+P+   + +  + +QR +LE ++  LP +   + SS     L  LL+TA     S S ++ LE++I   L+QA L+D+LIP+       +YD D ++RI   FL+  E       + E +  +++ +         S +  ++  V KL+D YL+E+A D++L P KF  LA  LPD AR   DGLYRAVD++LK HP + +SER ++C  + C+KL+ +A +HAAQNERLP++  VQVLF+EQ +L++A+        +        P  +G  SG                     M+ G        A+V REN+ LRL++  MR R+  LE++  +MK+
Sbjct:   76 LNLAAVPGGSESFELAAKFCYGVGVQYNSSNIAALRCVAHYLEMTEDLSEKNLEARTEAYLKDSIFNDISNSITVLHSCERLLPVAEEINLVGRLVNAIAVNACK---------------EQLASGLLKLDQSFSCGVPETA----KPCDWWGRSLPILKLDFFQRVLSAMKSKGLNHDIISDILMSYARKSLQII----REPNLVKSDSDLQRKQRIVLEAVVGLLPTQA--NKSSIPISFLSSLLKTAIGSGTSVSCRSDLERRISHLLDQAILEDILIPANI---GAMYDTDSVQRIFSMFLNLDECEYRDDDDDEEDAVDESEMAMYDFEGAESPKQSSIFKVSKLMDSYLAEVALDSSLPPSKFIALAELLPDHARVVCDGLYRAVDIFLKVHPHMKDSERYRLCKTVSCKKLSQDASSHAAQNERLPVQIAVQVLFYEQTRLKNAMTSGGGTGGSNQSQFFLFPNRSG--SG---------------------MASGAISPRDNYASVRRENRELRLEVARMRMRLTDLEKDHVSMKR 568          

Query:  218 LLMKASATFSDQISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYI-----PGTSRSNRKPXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIA 1588
            L+M++  +   +I+L D PGG + FE AAKFCYGV  +++   V  L CAAEFL+MTD+Y ++NL  +T+ FLSQ    SL  +I  LKSCE ++ ++  LGIV R +D +  +A +        P N              W                    W E+L +L +  F  ++S++K+R + P  + S ++ Y +K +       + R  +        +   S+QR+L+++I+S LP +K           L  LLR A  L+ S + K  LEK+I   LE  ++DDLLIPS++Y  E L D+D + RI+  F++  +E+N       N G+ +  + S    +L  V K +D YL+EIA+  +L   KF  +A  +P  AR  DD LYRA+D++LKAHP + E EREK+C  +D  KL+ +A  HA+QN+RLP+  V+  L+++QL+LR  +A
Sbjct:   60 LIMESKDSDVTRINLSDIPGGPEIFEKAAKFCYGVNFEITVQNVAALHCAAEFLQMTDKYCDNNLAGRTQDFLSQVALSSLSGAIVVLKSCEILLPISRDLGIVRRCVDVVGAKACNEAMFPCRTPPN--------------W--------------------WTEELCILDVDFFSDVVSSMKQRGVKPSSLASAIITYTEKSLRDLVRDHSGRGVKYSDPGDNESDERSQQRDLVQSIVSLLPSDK----GLFPVNFLCSLLRCAVFLDTSLTCKNELEKRISVVLEHVSVDDLLIPSFTYDGERLLDLDSVRRIISAFVE--KEKNVGVF---NGGDFNRGVCSV---SLQRVAKTVDSYLAEIATYGDLTISKFNAIANLVPKSARKSDDDLYRAIDIFLKAHPNLDEIEREKVCSSMDPLKLSYDARLHASQNKRLPVNIVLHALYYDQLKLRSGVA 475          

Query:  146 SHYCIHKCKARKRVEELTRVEAMLLLMKASATFSDQISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLKRR-DLSPEVIESCLMCYAKKYIPGTSRSNRKPXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIINSSRLPALM------LVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETAPMNAGR 1633
            S +C+HK     +   L +     LL        D I +   PGG  AFET AKFCYG+ + LS+  VV  RCAAE+L M +   + NLI K + FLS S+F+S K SI  L++ +  + L+E L +V   ID+IA +A   D +   W       + K A      NG ++       AR    + W EDL  L +  +KR+I  +K +  L  EVI   L  Y  + + G ++        +       + + ++ET++  LP EK    +S +   L  LL+   ++N+ E  K  L ++IG QLE+A++ +LLI S+   +ETLYDVD +++I+  F+    ++N+  IE +++ +   +    +LP ++      +V K+ID YL+EIA D NL   KF ++A S+    R   D LYRA+D++LK HP I + E++++C ++DC+KL++EAC HA QN+RLPLR VVQVLFFEQ++   A A +  +    P   GR
Sbjct:   38 SRFCLHKFPLLSKCACLQK-----LLSSTDKNNIDDIDISGIPGGPTAFETCAKFCYGMTVTLSAYNVVATRCAAEYLGMHETVEKGNLIYKIDVFLSSSLFRSWKDSIIVLQTTKPFLPLSEDLKLVSLCIDAIATKAC-VDVSHVEWSYTYN--KKKLAEEN---NGADS-----IKARDVPHDWWVEDLCELEIDYYKRVIMNIKTKCILGGEVIGEALKAYGYRRLSGFNKG-------VMEQGDLVKHKTIIETLVWLLPAEK----NSVSCGFLLKLLKAVTMVNSGEVVKEQLVRRIGQQLEEASMAELLIKSHQG-SETLYDVDLVQKIVMEFMR--RDKNSE-IEVQDDEDGFEVQEVRKLPGILSEASKLMVAKVIDSYLTEIAKDPNLPASKFIDVAESVTSIPRPAHDALYRAIDMFLKEHPGITKGEKKRMCKLMDCRKLSVEACMHAVQNDRLPLRVVVQVLFFEQVR---AAASSGSSTPDLPRGMGR 506          

Query:  248 DQISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVES-----WFEDLALLSLPLFKRLISTLKRRD-LSPEVIESCLMCYAKKYIPGTSRSNRKPXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIINSSRLPALMLVGKLIDGYLSEIAS-DANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQ 1570
            D+I + D PGG  AFE  AKFCYG+ + L++  VV +RCAAE+LEM +     NL+ K E FL+ SV +S K SI  L++  S    +E + +  R ++SIAL+A+  DP    W                      T  RRK L    N  S     W EDLA LS+ LFKR++ST++R+  + PEVI   L  YA K IPG    N              EQR LLET++S LP EK     S +   L  LL+++      E  +  L ++IG +LE+A + DLLI +     ET+YD+D +E ++  F+   E+R+           +D+I +SS+      V KLIDGYL+EI+  + NL   KF  +A  +    R   DG+YRA+D++LK HP I +SE++    ++DC+KL+ EAC HA QNERLPLR VVQ+LFFEQ++
Sbjct:   70 DEIRIPDIPGGPPAFEICAKFCYGMAVTLNAYNVVAVRCAAEYLEMYESIENGNLVYKMEVFLNSSVLRSWKDSIIVLQTTRSFYPWSEDVKLDVRCLESIALKAA-MDPARVDWSY--------------------TYNRRKLLPPEMNNNSVPRDWWVEDLAELSIDLFKRVVSTIRRKGGVLPEVIGEALEVYAAKRIPGFMIQNDD----NDDEEDVMEQRSLLETLVSMLPSEK----QSVSCGFLIKLLKSSVSFECGEEERKELSRRIGEKLEEANVGDLLIRAPEG-GETVYDIDIVETLIDEFVTQTEKRDELDC-------SDDINDSSKAN----VAKLIDGYLAEISRIETNLSTTKFITIAEKVSTFPRQSHDGVYRAIDMFLKQHPGITKSEKKSSSKLMDCRKLSPEACAHAVQNERLPLRVVVQILFFEQVR 476          

Query:  254 ISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSP-EVIESCLMCYAKKYIPGTSRSNRKPXXXX------XXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFL---------------DGLEERNAAGIEAEN---EGNNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQ 1564
            I L +FPGG +AFE  AKFCYG+ I +S+  +V  RCAAE+L+M++E  + NL+ K E F +  +    + SI  L++ ++    +E L I  R I++IA +  S          +   V    + ++ + +   +  R  A +R      W ED+A L + L+ R +  +K     P  +I   L  YA K++P   R NRK           +   + S+ R LLE+IIS LP EK   S S     L  LL+ ANILNAS SSK  L +++  QLE+AT+ DLLIP  SY +E LYDVD +  IL  F+                G+ +R      AEN   E       +S+   + + V KL+DGYL +IA D NL   KF  LA S+P+ +R   D LYRA+D+YLKAH  + +SER+++C VLDC+KL++EAC HAAQNE LPLR VVQVLF+EQ
Sbjct:   65 IQLPEFPGGVEAFELCAKFCYGITITISAYNIVAARCAAEYLQMSEEVEKGNLVYKLEVFFNSCILNGWRDSIVTLQTTKAFPLWSEDLAITSRCIEAIASKVLS----------HPSKVSLSHSHSRRVRDDDMSSNRAAASSRG----WWAEDIAELGIDLYWRTMIAIKSGGKVPASLIGDALRVYASKWLPTLQR-NRKVVKKKEDSDSDSDTDTSSKHRLLLESIISLLPAEKGAVSCS----FLLKLLKAANILNASTSSKMELARRVALQLEEATVSDLLIPPMSYKSELLYDVDIVATILEQFMVQGQTSPPTSPLRGKKGMMDRRRRSRSAENIDLEFQESRRSSSASHSSKLKVAKLVDGYLQQIARDVNLPLSKFVTLAESVPEFSRLDHDDLYRAIDIYLKAHKNLNKSERKRVCRVLDCKKLSMEACMHAAQNEMLPLRVVVQVLFYEQ 507          

Query:  254 ISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYS---EDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGA--SAQALWNGIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLK--RRDLSPEVIESCLMCYAKKYIPGTSRSNRKPXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGL-----------EERNA-----AGIEAENEGNNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQ 1564
            I L DFPG ++AFE  AKFCYG+ I L +  VV +RCAAE+L MT+E      +NL+ + E FL+  VFKS + S   L++ + +   +E LGI  R I++IA   + +    F   +  G++  +      + L NG          ++  ++  W EDLA L L L++R +  +K   R +SP +I + L  YA K++P    S+   +              +LE++IS LP EK    SS     L  LL+ AN++N S SSK  L  K G QL++AT+ +LLIP  S  +  LYDVD ++ ++  FL  +           E R +       +E   E       +SS  P L  V KL+D YL EIA D NL   KF  LA ++PD +R   D LY A+DVYL+ H  I + ER+++C +LDC+KL++EA   AAQNE LPLR +VQ+LF EQ
Sbjct:   71 IQLVDFPGETEAFELCAKFCYGITITLCAHNVVAVRCAAEYLGMTEEVELGETENLVQRLELFLTTCVFKSWRDSYVTLQTTKVLPLWSEDLGITNRCIEAIANGVTVSPGEDFSTQLETGLLRNRSRIRRDEILCNG-------GGGSKAESLRWWGEDLAELGLDLYRRTMVAIKSSHRKISPRLIGNALRIYASKWLPSIQESSADSNL-------------VLESVISLLPEEK----SSVPCSFLLQLLKMANVMNVSHSSKMELAIKAGNQLDKATVSELLIP-LSDKSGMLYDVDVVKMMVKQFLSHISPEIRPTRTRTEHRRSRSEENINLEEIQEVRGSLSTSSSPPPLLSKVAKLVDSYLQEIARDVNLTVSKFVELAETIPDTSRICHDDLYNAIDVYLQVHKKIEKCERKRLCRILDCKKLSVEASKKAAQNELLPLRVIVQILFVEQ 505          

Query:  248 DQISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVES------WFEDLALLSLPLFKRLISTLKRRDLSP-EVIESCLMCYAKKYIPGTSRSNRKPXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAG 1591
            D+I + + PGGS AFE   KFCYG+ + L++  VV +RCAAEFLEM + + + NL+ K + FL+ ++F+S K SI  L++ + +++  +S  +V+R + SIA  AS  D +   W                      T  R+K L +    E       W EDL  L + L+K+ I  +K R   P  VI   L  YA + I G S+ + +              R L+ TII  LP EK + SSS  T+L     R +  L   E+ K  L+K++  QLE+ T++D+L          +YD+D ++ ++  F+                 N D   +S      + V KLIDGYL+E + D NL  + F +LA +L    R+  D LYRA+D++LK H  I +SE++++CG++DC+KL+ EAC HA QNERLP+R +VQVLFFEQ++   +  G
Sbjct:   72 DEIDISEIPGGSVAFEICVKFCYGITVTLNAYNVVAVRCAAEFLEMNETFEKSNLVYKIDVFLNSTIFRSWKDSIIVLQTTKDLLS-DDSEELVKRCLGSIASTAS-IDTSKVKWSY--------------------TYNRKKKLEKVRKPEDGVPKDWWVEDLCELHIDLYKQAIKAIKNRGKVPSNVIGEALHAYAIRRIAGFSKESMQ-----------LIDRSLINTIIELLPDEKGNISSSFLTKLH----RASIFLGCEETVKEKLKKRVSEQLEETTVNDIL----------MYDLDMVQSLVKEFM-----------------NRDPKTHSK-----VSVAKLIDGYLAEKSRDPNLPLQNFLSLAETLSSFPRHSHDVLYRAIDMFLKEHSGISKSEKKRVCGLMDCRKLSAEACEHAVQNERLPMRVIVQVLFFEQIRANGSSTG 457          

Query:  218 LLMKASATFSDQISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVN--------DGIVEAKGASAQALWNGIETGLRRKALARTSNV---ESWFEDLALLSLPLFKRLISTLKRRD-LSPEVIESCLMCYAKKYIPGTSRSNRKPXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETAPM 1621
            L+ +AS   +D+I++ D PGG  AFE  AKFCYG+ + L++  +  +RCAAE+LEMT++    NLI K E FL+  +F+S K SI  L++  S++  +E L +V R IDS++ +    +P    W           D IVE                 R K   R  NV   + W ED+  L + +FKR+IS +K    ++  VI   L  Y  +++P +  S              S  ++L+ET++  LP +   + S ++   L  LL+ + ++ A E+ +  L + +  +L +A++ DLLI          ++V+ + RI+  F+   +E+  +    E++   + ++ +     L+ VG+LID YL   A ++ L    F  L+  +P+ AR   DGLY+A+D ++K HP + +SE++++CG++D +KLT EA THAAQNERLPLR VVQVL+FEQL+  H+   ++ A+  +P+
Sbjct:   57 LVFEASEEKTDEITILDMPGGYKAFEICAKFCYGMTVTLNAYNITAVRCAAEYLEMTEDADRGNLIYKIEVFLNSGIFRSWKDSIIVLQTTRSLLPWSEDLKLVGRCIDSVSAKIL-VNPETITWSYTFNRKLSGPDKIVEYH---------------REK---REENVIPKDWWVEDVCELEIDMFKRVISVVKSSGRMNNGVIAEALRYYVARWLPESMES---------LTSEASSNKDLVETVVFLLP-KVNRAMSYSSCSFLLKLLKVSILVGADETVREDLVENVSLKLHEASVKDLLI----------HEVELVHRIVDQFM--ADEKRVS----EDDRYKEFVLGNG---ILLSVGRLIDAYL---ALNSELTLSSFVELSELVPESARPIHDGLYKAIDTFMKEHPELTKSEKKRLCGLMDVRKLTNEASTHAAQNERLPLRVVVQVLYFEQLRANHSPVASVAASSHSPV 485          

Query:  251 QISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYIPGTSRSNRKPXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETAPMNAGRLSGTXXXXXXXXXXXXXXXXXXVAMSRGEQGSTTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIQKIEKGNPRGSGWRGSLNKRLGCKFKTQVCDSHESTVTETXXXXXXXXQE 1993
            QISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFKSLKASIKALKSCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYIPGTSRS+RKPSSSLAAAISESEQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETAPMNAGRLSGTRRDDDEEEE+QQDEEEERVAMSRGEQGSTTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIQKIEKGNPRGSGWRGSLNKRLGCKFKTQVCDSHESTVTETRRRRHHHHQE
Sbjct:   97 QISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFKSLKASIKALKSCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYIPGTSRSSRKPSSSLAAAISESEQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETAPMNAGRLSGTRRDDDEEEEEQQDEEEERVAMSRGEQGSTTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIQKIEKGNPRGSGWRGSLNKRLGCKFKTQVCDSHESTVTETRRRRHHHHQE 677          

Query:  251 QISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYIPGTSRSNRKPXXXXXXXXXXX-XQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEG--NNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETAPMNAGRLSGTXXXXXXXXXXXXXXXXXXVAMSRGEQGSTTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIQKIEKGNPRGSGWRGSLNKRLGCKFKTQVCDSHESTVTET 1963
            QISL DFPGGS+ FE AAKFCYGVKIDLSSSTVVPLRCAAEFLEMT+EYSE NLISKTERFLSQSVFKSLK S+KALKSCESVM+LAESLGIV+RLI+SIA RASSTDPTLFGWPVNDGIVEAKGAS+QALWNGIETGLRRK+L RT+NVESWFEDLALLSLPLFKRLI TLK RDLSPE+IESCLMCYAKKYIPGTSRSNRKPS+S +A+     EQRELLETIISNLPLEK+ + SSTATR LFGLLRTANILNASES KAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNA GIEAE  G  NN    NS R PALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQAR FDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAE AP NAGRLS       EEE+++++E    V++SRGE+GS+TWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVI+KI+K  PRG GWRGSLN+R GCKF+TQVCDSHESTVTET
Sbjct:  194 QISLPDFPGGSETFEGAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTEEYSEGNLISKTERFLSQSVFKSLKESVKALKSCESVMSLAESLGIVQRLIESIAARASSTDPTLFGWPVNDGIVEAKGASSQALWNGIETGLRRKSLGRTNNVESWFEDLALLSLPLFKRLILTLKTRDLSPEIIESCLMCYAKKYIPGTSRSNRKPSTSSSASGVSEGEQRELLETIISNLPLEKSPTRSSTATRFLFGLLRTANILNASESCKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAEGIEAETRGNNNNILNNNSVRPPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARLFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAEAAPTNAGRLS---EAMREEEDEEEEERAGVVSVSRGEEGSSTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIEKIDKEGPRGGGWRGSLNRRFGCKFRTQVCDSHESTVTET 764          

Query:  251 QISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYIPGTSRSNRKPXXXXXXXXXXX-XQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIIN--SSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETAPMNAGRLSGTXXXXXXXXXXXXXXXXXXVAMSRGEQGSTTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIQKIEKGNPRGSGWRGSLNKRLGCKFKTQVCDSHESTVTET 1963
            QISL DFPGGS+ FE AAKFCYGVKIDLSSSTVVPLRCAAEFLEMT+EYSE                                   AESLGIV+RLI+SIA RASSTDPTLFGWPVNDGIVEAKGAS+QALWNGIETGLRRK+L RT+NVESWFEDLALLSLPLFKRLI TLK RDLSPE+IESCLMCYAKKYIPGTSRSNRKPS+S +A+     EQRELLETIISNLPLEK+ + SSTATR LFGLLRTANILNASES KAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNA GIEAE  GNN+NI+N  S R PALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQAR FDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAE AP NAGRLS       EEE+++++E    V++SRGE+GS+TWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVI+KI+K  PRG GWRGSLN+R GCKF+TQVCDSHESTVTET
Sbjct:   95 QISLPDFPGGSETFEGAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTEEYSE-----------------------------------AESLGIVQRLIESIAARASSTDPTLFGWPVNDGIVEAKGASSQALWNGIETGLRRKSLGRTNNVESWFEDLALLSLPLFKRLILTLKTRDLSPEIIESCLMCYAKKYIPGTSRSNRKPSTSSSASGVSEGEQRELLETIISNLPLEKSPTRSSTATRFLFGLLRTANILNASESCKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAEGIEAETRGNNNNILNNNSVRPPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARLFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAEAAPTNAGRLS---EAMREEEDEEEEERAGVVSVSRGEEGSSTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIEKIDKEGPRGGGWRGSLNRRFGCKFRTQVCDSHESTVTET 630          

Query:  251 QISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKAL----------ARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYIPGTSRSNRKPXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETAPMNAGRLSGTXXXXXXXXXXXXXXXXXXVAMSRGEQGSTTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIQKIEKGNPRGSGWRGSLNKRLGCKFKTQVCDSHESTVT 1957
            QI+L DFPGGS  FE AAKFCYGVK+DL+SSTV PLRCA EFLEMT+EYSEDNL+SKTERFLSQSV KSLK SIKALKSCE VM LAESLGI +R IDSIA RASS DP LFGWPV+DG  E K  S QALWNGIE+ +RRK             R +NV SWFE L LLSLPLFKRLI  ++ RDLSP++IESCLM YAKKYIPG    NRKPSSS + A      RE+LETIISNLPLEK+ S SSTATR LFGL RTANILNASES ++ALEKKIG QLEQATLDDLLIPSYSYLNETLYDVDC+ERILGYFLDGLEERNAAG+EAE E  + N+    R PALMLVGKLIDGYL+EIASDANLKP++FYNLAISLP+QAR FDDGLYRAVDVYLKAHPWI E+EREKIC V+DCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTL+A ETAP    RLS          EQ+  EE      +   + STTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVI KI+K  PR  GWRGSL K+LGCKFKTQVC+SHE  V 
Sbjct:   80 QITLPDFPGGSQTFEMAAKFCYGVKVDLTSSTVAPLRCAGEFLEMTEEYSEDNLVSKTERFLSQSVLKSLKESIKALKSCEKVMPLAESLGITQRCIDSIASRASSADPALFGWPVSDGTNENKPISNQALWNGIESAVRRKGAATASTAAAFGGRFANVASWFEYLGLLSLPLFKRLILAMRARDLSPQIIESCLMLYAKKYIPGVCTLNRKPSSSSSIASESE-HREVLETIISNLPLEKS-SRSSTATRFLFGLFRTANILNASESCRSALEKKIGSQLEQATLDDLLIPSYSYLNETLYDVDCLERILGYFLDGLEERNAAGVEAEEEEGDRNV----RSPALMLVGKLIDGYLAEIASDANLKPDRFYNLAISLPEQARLFDDGLYRAVDVYLKAHPWISEAEREKICAVMDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLIATETAPQETARLS------LIRREQEDVEEGAAATAAAEARESTTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIDKIDKDGPR--GWRGSLTKKLGCKFKTQVCNSHEQAVV 644          

Query:  251 QISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVE-AKGASAQALWNGIETGLRRKAL-ARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYIPGTSRSNRKPXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGL-EERNAAGIEAENEGNNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETAPMNAGRLSGTXXXXXXXXXXXXXXXXXXVAMSRGEQGSTTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIQKIEKGNPRGS--GWRGSLNKRLGCKFKTQVCDSHESTVT 1957
            QISL DFPGGS+ FE AAKFCYGVK+DL+SS + PLRCA EFLEMT+EYSEDNLISKTERF S SV KSLK SIKALKSCE VM LAESLGI ER IDSI  RASS DP LFGWPV++   E  K +S QALWNGIE+ +RRK   AR++N +SWFEDLALLS+PLFKRLI  +K RDL+PE++ESCLM YAKK+IPG SR +RKPSSS ++  SE  QRE+LET +SNLPL ++ S SSTATR LFGLLRTANILNA+E  ++ LEKKIG QLEQATLDDLLIPSYSYLNETLYDVDC+ERILG+FLDGL EERN   IEA  +G + N+    R P LMLVGKLIDGYL+EIASDANLKP++F+NLAISLP+QAR FDDGLYRAVDVYLKAHPWI E+EREKICGV+DCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTL+AAE  P     L    R  +EE E +   E E  AM  G   S TWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVI KI+K  PRG+  GWR SL +R GCKFKTQVCDSHE TV 
Sbjct:  136 QISLLDFPGGSETFEMAAKFCYGVKVDLNSSIIAPLRCAGEFLEMTEEYSEDNLISKTERFFSHSVLKSLKESIKALKSCERVMALAESLGITERCIDSIISRASSADPALFGWPVSEAANENIKASSNQALWNGIESAVRRKGGGARSNNADSWFEDLALLSMPLFKRLILAMKVRDLNPEILESCLMYYAKKHIPGISRLSRKPSSSSSSIASEGGQREVLETTVSNLPLHRS-SRSSTATRFLFGLLRTANILNAAEECRSTLEKKIGLQLEQATLDDLLIPSYSYLNETLYDVDCLERILGHFLDGLQEERNVGEIEAGEDGGDSNV----RSPTLMLVGKLIDGYLAEIASDANLKPDRFHNLAISLPEQARLFDDGLYRAVDVYLKAHPWISEAEREKICGVMDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLIAAEADPARPSML----RRREEEAEAEAGAEAEAGAMQEGT--SNTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIDKIDKEGPRGNNGGWRESLTRRFGCKFKTQVCDSHEQTVV 698          

Query:  251 QISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYIPGTSRSNRKPXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAE-NEGNNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETAPMNAGRLSGTXXXXXXXXXXXXXXXXXXVAMSRGEQGSTTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIQKIEK--GNPRGSGWRGSLNKRLGCKFKTQVCDSHESTVTET 1963
             ISL DFPGGS+  ETAAKFCYGVKI+LS+S V PLRCA EFLEMT+EYSEDNLIS+TER+LSQSV  S+K SIK LKSCE +M LAE+L I +R I++IA RA S DP+LFGWPVNDG    +G+S   LWNGIET +RRK  +RT+  +SW E+LALLSLPLFKRLI  ++ RDLSP+VIESCLM YAKKYIPG SRSNRKP SS   + +E  QRELLE II+NLP E + S SS ATR LFGLLRTANILNASE+S+AALE+KIG QLEQATLDDLLIPSYSYLNETLYDVDC+ERILGYFLDGLE    AGIE E  +G       S R PA+MLVGKLIDGYLSEIASDANLKP+KFY LAI+LP+ AR FDDGLYRAVDVYLKAHPW+ E EREKICGV+DCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAI G++LAAE AP ++GR S  + + + E                  Q  +TWRAAVRENQVLRLDMDSMR+RVH+LERECSTMKK I+KI++   +  G GWRGSL KR GCKFKTQVCDSHE +V ET
Sbjct:   81 HISLPDFPGGSETLETAAKFCYGVKIELSASNVAPLRCAGEFLEMTEEYSEDNLISRTERYLSQSVLISVKESIKTLKSCEGLMPLAETLDIPQRCIEAIAERALSADPSLFGWPVNDG----RGSSNPLLWNGIETSVRRKGTSRTTTSDSWLEELALLSLPLFKRLILAMRARDLSPDVIESCLMYYAKKYIPGISRSNRKPPSSSVVSETE--QRELLEAIITNLPSENS-SRSSIATRFLFGLLRTANILNASEASRAALERKIGSQLEQATLDDLLIPSYSYLNETLYDVDCVERILGYFLDGLE----AGIEGEIGDG-------SIRPPAMMLVGKLIDGYLSEIASDANLKPDKFYELAIALPENARLFDDGLYRAVDVYLKAHPWVAEEEREKICGVMDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAITGSILAAEAAPPDSGRPSNLQLEQEGESAVG------------AAQDVSTWRAAVRENQVLRLDMDSMRSRVHELERECSTMKKAIEKIDQLGPSGGGGGWRGSLTKRFGCKFKTQVCDSHEPSVVET 624          

Query:  251 QISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYIPGTSRSNRK---PXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETAPMNAGRLSGTXXXXXXXXX----XXXXXXXXXVAMSRGEQGSTTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIQKIEK-GNPRGSG--WRGSLNKRLGCKFKTQVCDSHESTV 1954
             I L DFPGGSD FE A+KFCYGVKIDL+SS V PLRCA EFLEMT+EYS +NLISKTE++LSQ+V +S+K SIK LKSCE VM LAE+L I +R IDSIA +A S DP LFGWPV+DG   A+  S Q LWNGIETG R+K+  R S   SWFEDLA LSLPLFKRLI +++ RD+S E+IESCLM YAKKYIPG SRSNRK   PS+S ++  +E++Q+ELLETIISNLPLEK+ S + TATR LFGLLRTANILNASE  KAALEKKIG QLEQATLDDLLIPSYSYLNETLYDVDC ERIL YFL+GLEE+NA   E       D   + +R PALMLVGKLIDGYL+EIASD NLK E+FYNLAISLP+QAR FDDG+YRAVDVYLKAHPWI E+EREKICGV+DCQKLTLEACTHAAQN+RLPLRAVVQVLFFEQLQLRHAIAGTL+AAET P + GR SG  R + E+ E    ++ +EEEE +        + TWR  VRENQ+LRLDMDSMRTRVHQLERECSTMKKVI+KI+K G+P+G+G  WR SL +RLGCKFKTQVCDSHES V
Sbjct:  100 HIVLSDFPGGSDIFEMASKFCYGVKIDLNSSNVAPLRCAGEFLEMTEEYSVENLISKTEKYLSQTVLRSIKESIKTLKSCEPVMPLAETLSITQRCIDSIASKAPSADPALFGWPVSDGANSAQDQSKQMLWNGIETGGRKKSGGRGSKGGSWFEDLAQLSLPLFKRLIFSMRDRDVSSEIIESCLMNYAKKYIPGISRSNRKPSLPSASSSSMPTETDQKELLETIISNLPLEKS-SKTPTATRFLFGLLRTANILNASEVCKAALEKKIGSQLEQATLDDLLIPSYSYLNETLYDVDCAERILSYFLEGLEEKNAEVAEVNQAVVED---DGTRSPALMLVGKLIDGYLAEIASDGNLKAERFYNLAISLPEQARLFDDGVYRAVDVYLKAHPWISEAEREKICGVMDCQKLTLEACTHAAQNDRLPLRAVVQVLFFEQLQLRHAIAGTLMAAETVPADTGRFSGVSRRETEDVERGVGEELEEEEEEIPAGAIVHENGTWRETVRENQMLRLDMDSMRTRVHQLERECSTMKKVIEKIDKAGSPQGNGGRWRASLIRRLGCKFKTQVCDSHESAV 673          

Query:  251 QISLQDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVN-------DGIVEAKGASAQALWNGIETGLRRKALARTS-NVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYIPGTSRSNRKP---------XXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTATRLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETAPMNAGRLS-------GTXXXXXXXXXXXXXXXXXXVAMSRGEQGSTTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIQKIEK-GNPR--GSGWRGSLNKRLGCKFKTQVCDSHESTVTET 1963
            QI+L DFPGGS+ FE AAKFCYGVKIDLSSS V PLRCA E+LEMT+EYSEDNLISKTERFLSQSV KS K S+KALKSCE VM LAE+LGI +  IDSIA RA+S DPTLFGWPV+       + I  +     Q LWNGI+ G         S + +SW EDL +LSLPLFKRLIS +K  DLS E++E+CLM YAKKYIPG SR+NRKP         +++ ++  SES+QRELLETIISNLPLEK+ S  STATR LFGLLRTANILNASE+ KAALEKKI  QL QATLDDLLIPSYSYLNETLYDVDC+ERILGYFL GL++RN AGI     G +D    + R P LMLVGKLID +LSEIASDANLKP++FYNLAISLP+QAR FDDGLYRAVD+YLKAHPWI E EREKICG+LDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLA + AP ++GR S       G   +++++ E + +E+ + VA +    G  TWRAAVRENQVLRLDMDSMRTRVHQLERECS MKKVI+KI+  G PR  GS W+ SL++R GCKFKTQVCDSHE+T  +T
Sbjct:   85 QIALSDFPGGSETFEIAAKFCYGVKIDLSSSNVAPLRCAGEYLEMTEEYSEDNLISKTERFLSQSVLKSFKESLKALKSCERVMPLAETLGITQTCIDSIASRATSADPTLFGWPVSEAPNANTNAISSSSSTKQQILWNGIDAGGGGGRRRGLSKHADSWVEDLVVLSLPLFKRLISAMKSGDLSLEMVETCLMHYAKKYIPGISRTNRKPPSSISAVTATTTSSSLASESQQRELLETIISNLPLEKS-SRPSTATRFLFGLLRTANILNASEACKAALEKKIASQLHQATLDDLLIPSYSYLNETLYDVDCVERILGYFLKGLDQRNTAGI-----GEDDGSDGAVRSPTLMLVGKLIDEFLSEIASDANLKPDRFYNLAISLPEQARLFDDGLYRAVDLYLKAHPWITEPEREKICGILDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLATDVAPPDSGRPSVLQRERQGEEEEEEDDAEARAEEDGDNVARANN-SGGGTWRAAVRENQVLRLDMDSMRTRVHQLERECSNMKKVIEKIDNPGQPRRDGSVWKDSLSRRFGCKFKTQVCDSHEATAVDT 675          

Query:  263 QDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYIPGTSRS-NRKPXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTAT-RLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETAPMNAGRLSGTXXXXXXXXXXXXXXXXXXVAMSRGEQGSTTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIQKIEKGNPRGSGWRGSLNKRLGCKFKTQVCDSHESTVTE 1960
            +DFPGGS+ FE  AKFCYGVK++LSSS V PLRCA E+LEMT+E++ DNLISKTERFLSQSVFKSLK SI+ALKSCE+V++ AESLGI+ R IDSIALRASS DP LFGWPV +G      AS Q LWNGIET LRRK   RTS  +SWFEDL+ L+LP FKRLI+ +K RD+S E+IESCLM YAKK+IPG  RS + +  SS +   SESEQRELLET+I+NLPL+K+ S++ST + R LFGLLR ANILNASES ++ALE KIG QL+QATLDDLLIPSYSYLNETLYDV+C+ERILGYFLDGL+          +E N +   ++SR P LMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQAR FDDGLYRAVD+YLKAH WIPE+EREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLL+AE AP  AGR SG               +EE         GS TWR AVRENQVLRLDMDSMRTRVHQLERECSTMKKVI+ I+K  P G GW+GSL ++ GCKFKTQVCDSHE TV +
Sbjct:   59 EDFPGGSETFEMVAKFCYGVKMELSSSNVAPLRCAGEYLEMTEEFAGDNLISKTERFLSQSVFKSLKDSIRALKSCENVVSSAESLGIIRRCIDSIALRASSADPALFGWPVTEG--GGSSASNQNLWNGIETNLRRKN-GRTSESQSWFEDLSQLNLPFFKRLIAEMKSRDVSGEIIESCLMFYAKKHIPGIWRSGSSRKQSSPSTIPSESEQRELLETVIANLPLQKSSSATSTTSTRFLFGLLRAANILNASESCRSALEMKIGSQLDQATLDDLLIPSYSYLNETLYDVNCVERILGYFLDGLQ----------SEENRETTTSASRSPPLMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARLFDDGLYRAVDIYLKAHSWIPEAEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLSAEGAPQEAGRASGI-------------RQEEETEGEGEGSGSATWRVAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIENIDKKGPAG-GWKGSLTRKFGCKFKTQVCDSHEQTVVD 599          

Query:  263 QDFPGGSDAFETAAKFCYGVKIDLSSSTVVPLRCAAEFLEMTDEYSEDNLISKTERFLSQSVFXXXXXXXXXXXXCESVMTLAESLGIVERLIDSIALRASSTDPTLFGWPVNDGIVEAKGASAQALWNGIETGLRRKALARTSNVESWFEDLALLSLPLFKRLISTLKRRDLSPEVIESCLMCYAKKYIPGTSRS-NRKPXXXXXXXXXXXXQRELLETIISNLPLEKTHSSSSTAT-RLLFGLLRTANILNASESSKAALEKKIGFQLEQATLDDLLIPSYSYLNETLYDVDCIERILGYFLDGLEERNAAGIEAENEGNNDNIINSSRLPALMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARNFDDGLYRAVDVYLKAHPWIPESEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLAAETAPMNAGRLSGTXXXXXXXXXXXXXXXXXXVAMSRGEQGSTTWRAAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIQKIEKGNPRGSGWRGSLNKRLGCKFKTQVCDSHESTVTE 1960
            +DFPGGS+ FE  AKFCYGVK++LSSS V PLRCA E+LEMT+E++ DNLISKTERFLSQSVFKSLK SI+ALKSCE+V++ AESLGI+ R IDSIALRASS DP LFGWPV +G      AS Q LWNGIET LRRK   RTS  +SWFEDL+ L+LP FKRLI+ +K RD+S E+IESCLM YAKK+IPG  RS + +  SS +   SESEQRELLET+I+NLPL+K+ S++ST + R LFGLLR ANILNASES ++ALE KIG QL+QATLDDLLIPSYSYLNETLYDV+C+ERILGYFLDGL+          +E N +   ++SR P LMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQAR FDDGLYRAVD+YLKAH WIPE+EREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLL+AE AP  AGR SG               +EE         GS TWR AVRENQVLRLDMDSMRTRVHQLERECSTMKKVI+ I+K  P G GW+GSL ++ GCKFKTQVCDSHE TV +
Sbjct:   88 EDFPGGSETFEMVAKFCYGVKMELSSSNVAPLRCAGEYLEMTEEFAGDNLISKTERFLSQSVFKSLKDSIRALKSCENVVSSAESLGIIRRCIDSIALRASSADPALFGWPVTEG--GGSSASNQNLWNGIETNLRRKN-GRTSESQSWFEDLSQLNLPFFKRLIAEMKSRDVSGEIIESCLMFYAKKHIPGIWRSGSSRKQSSPSTIPSESEQRELLETVIANLPLQKSSSATSTTSTRFLFGLLRAANILNASESCRSALEMKIGSQLDQATLDDLLIPSYSYLNETLYDVNCVERILGYFLDGLQ----------SEENRETTTSASRSPPLMLVGKLIDGYLSEIASDANLKPEKFYNLAISLPDQARLFDDGLYRAVDIYLKAHSWIPEAEREKICGVLDCQKLTLEACTHAAQNERLPLRAVVQVLFFEQLQLRHAIAGTLLSAEGAPQEAGRASGI-------------RQEEETEGEGEGSGSATWRVAVRENQVLRLDMDSMRTRVHQLERECSTMKKVIENIDKKGPAG-GWKGSLTRKFGCKFKTQVCDSHEQTVVD 628